Showing 841 - 860 results of 1,774 for search '(( a non decrease ) OR ( 10 ((((we decrease) OR (mean decrease))) OR (a decrease)) ))', query time: 0.17s Refine Results
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    Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

    Published 2019
    “…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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  6. 846

    Contrasting cardiovascular mortality trends in Eastern Mediterranean populations: Contributions from risk factor changes and treatments by Critchley, Julia

    Published 2016
    “…Background Middle income countries are facing an epidemic of non-communicable diseases, especially coronary heart disease (CHD). …”
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    Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse by Ahmedna, Mohamed

    Published 2016
    “…Results show that cell viability decreased to 93 ± 3%, 83 ± 6%, 65 ± 4% and 39 ± 3% at 10, 25, 50 and 100 mM of glucose on day 1 with further drastic decrease in cell viability to 73 ± 5%, 61 ± 3%, 35 ± 2%, and 11 ± 6%, respectively, on day 4 compared to the untreated cell. …”
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  15. 855

    Response of cauliflower (Brassica oleracea L.) to nitric oxide application under cadmium stress by Jing, Ma

    Published 2022
    “…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …”
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  16. 856

    An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems by Abdel-Salam, Mahmoud

    Published 2024
    “…However, these methods tend to converge towards local solutions with a low convergence rate. In order to address this issue in GKSO, a more refined version called I-GKSO is implemented. …”
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  17. 857

    Experimental investigation on the compressibility of Al/Al2O3 nanocomposites by Wagih, Ahmed

    Published 2016
    “…The results showed that the grain size of milled powders was about 43 nm with a noticeable presence of agglomerates at 10 wt.% of Al2O3. …”
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    PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells by Banasavadi-Siddegowda, Y K

    Published 2017
    “…Glioblastoma (GBM) represents the most common and aggressive histologic subtype among malignant astrocytoma and is associated with poor outcomes because of heterogeneous tumour cell population including mature non-stem-like cell and immature stem-like cells within the tumour. …”
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