JNJ26993135 + BML-111 decreases permeability and enhances ZO-1 and claudin-1 induced by PAF but does not change TEER. by Kameljit K. Kalsi (16496511)

Incubation in Normal Saline (NS) or Plasma-Lyte (PL) rendered acidic leads to decreased endothelial dependent relaxation in intact naïve porcine saphenous veins (PSV). by Joyce Cheung-Flynn (344249)

IL-18 disrupts and redistributes β-catenin in adherent junctions in HT-29 monolayers. by Ossama Allam (5043434)

<i>L.</i><i>interrogans</i> induces afadin degradation in infected RPTECs through different strain-dependent mechanisms. by Tetsuya Kakita (4922584)

Proteosomal and pan-caspase inhibitors differentially prevent the disruption of the epithelial cell barrier by the clinical <i>Leptospira</i> isolates. by Tetsuya Kakita (4922584)

Immunofluorescence analysis for F-actin in RPTECs infected with Oki53 and Oki65 at 24 h post-infection. by Tetsuya Kakita (4922584)

Immunofluorescence analysis using dual staining for E-cadherin (E-cad) and afadin and F-actin in RPTECs infected with Oki53 and Oki65 at 24 h post-infection. by Tetsuya Kakita (4922584)

Hypothetical model representing the distinct strategies of epithelial barrier disruption by Oki strains. by Tetsuya Kakita (4922584)

CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

P2X7 modulates migration and the epithelial-mesenchymal phenotype. by José David Nuñez-Ríos (18823719)

Changes in TEER and permeability of EA.hy926 cells exposed to EVs or pellets from infected or uninfected macrophages. by Myriam Lucia Velandia-Romero (8259726)

Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways by Joyce Cheung-Flynn (344249)

Expression of tight junction proteins. by Maj Schneider Thomsen (10297019)

Expression and functionality of efflux transporters. by Maj Schneider Thomsen (10297019)

Image_1_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_4_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_2_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_3_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Kinetics and dose response of distinct changes to HDMEC barriers induced by TNF and IL-β. by Paul R. Clark (714064)

“…B: TNF induction of an early TEER rise and a bi-phasic TEER decrease. Labels indicate the peak of the early TEER increase and two distinct phases of TEER decrease (as nadirs to phases 1 and 2). …”