Pathophysiological aspects of nephropathy caused by non-steroidal anti-inflammatory drugs by Guillherme Nobre Cavalcanti Lucas (5789135)

“…Factors such as advanced age and comorbidities, which in themselves already lead to a decrease in glomerular filtration rate, increase the risk of NSAID-related nephrotoxicity. …”

Treatment of cancer cells with vitamin D3 induced death <i>a.</i> by Vidya G. Bettada (22208808)

Graphs representing results (mean plus 95% confidence interval) of 100 deletions per each combination of deletion proportion (i.e., 0–20%) and type (i.e., random vs. targeted) in a... by Maggie Wiśniewska (11965538)

Mice subjected to chronic stress and provided with HRW exhibited a significant reduction in oxidative stress levels. by Qi He (384033)

Mice subjected to chronic stress and provided with HRW exhibited a significant reduction in lipid peroxidation levels. by Qi He (384033)

Table_2_Celecoxib and Etoricoxib may reduce risk of ischemic stroke in patients with rheumatoid arthritis: A nationwide retrospective cohort study.DOCX by Acer I-Hung Chen (13984755)

“…On the other hand, consuming Etoricoxib for 8 years might have a neutral or even a potentially protective effect compared to at 3.8 years.…”

Table_1_Celecoxib and Etoricoxib may reduce risk of ischemic stroke in patients with rheumatoid arthritis: A nationwide retrospective cohort study.DOCX by Acer I-Hung Chen (13984755)

“…On the other hand, consuming Etoricoxib for 8 years might have a neutral or even a potentially protective effect compared to at 3.8 years.…”

Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding. by Vanessa Beynon (153924)

“…A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca²⁺-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca²⁺-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”

Data Sheet 2_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip by Junhuang Zheng (21629486)

“…This meta-analysis aims to evaluate the prognostic value of LNR in patients with non-small cell lung cancer (NSCLC).</p>Methods<p>A systematic literature search was conducted in PubMed, Embase, Cochrane, and Web of Science databases, with the search date up to January 7, 2025. …”

Data Sheet 1_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip by Junhuang Zheng (21629486)

“…This meta-analysis aims to evaluate the prognostic value of LNR in patients with non-small cell lung cancer (NSCLC).</p>Methods<p>A systematic literature search was conducted in PubMed, Embase, Cochrane, and Web of Science databases, with the search date up to January 7, 2025. …”

Baseline characteristics. by Kai Yi Wu (16451082)

“…The overall incidence of readmission for stroke, bleeding, HF and ACS after non-cardiac surgery was low. The impact of male sex on clinical outcomes decreases with increasing age, suggesting the importance of considering the effect of both sex and age on clinical outcomes after non-cardiac surgery.…”

Outcomes stratified by sex. by Kai Yi Wu (16451082)

“…The overall incidence of readmission for stroke, bleeding, HF and ACS after non-cardiac surgery was low. The impact of male sex on clinical outcomes decreases with increasing age, suggesting the importance of considering the effect of both sex and age on clinical outcomes after non-cardiac surgery.…”

Clinical outcomes stratified by age. by Kai Yi Wu (16451082)

“…The overall incidence of readmission for stroke, bleeding, HF and ACS after non-cardiac surgery was low. The impact of male sex on clinical outcomes decreases with increasing age, suggesting the importance of considering the effect of both sex and age on clinical outcomes after non-cardiac surgery.…”

A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells by Min Hwa Shin (2541379)

“…<div><p>The inactivation of p53 creates a major challenge for inducing apoptosis in cancer cells. …”

Viability of FTY720-treated T_CM A. by Rachel S. Resop (9238645)

Minidysferlin do not improve muscle histology. A by William Lostal (162211)

“…Necrotic fibers, CNF, cellular infiltrations and fiber size variations are seen in both injected and non-injected <i>Dysf ^prmd</i> mice. Scale Bar=100 µm. …”

Fig 1 - by Kai Yi Wu (16451082)

Self-Reported Trait Mindfulness and Affective Reactivity: A Motivational Approach Using Multiple Psychophysiological Measures by Danielle Cosme (699818)

“…<div><p>As a form of attention, mindfulness is qualitatively receptive and non-reactive, and is thought to facilitate adaptive emotional responding. …”

3MC treatment of MCVECs increased the formation of AhR/c-Raf/pRb2/E2F1/HDAC1 complexes, with a concomitant decrease in E2F-driven luciferase activity. by Chih-Cheng Chang (540973)

HuR interacts with lincBRN1a and lincBRN1b during neuronal stem cells differentiation by Stephana Carelli (269728)