Data_Sheet_1_rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.docx by Munal B. Kandel (18526539)

“…<p>Chronic pain is common and inadequately treated, making the development of safe and effective analgesics a high priority. Our previous data indicate that carbonic anhydrase-8 (CA8) expression in dorsal root ganglia (DRG) mediates analgesia via inhibition of neuronal ER inositol trisphosphate receptor-1 (ITPR1) via subsequent decrease in ER calcium release and reduction of cytoplasmic free calcium, essential to the regulation of neuronal excitability. …”

Antibiotic treatment of wild type mice decreases bacterial load and does not produce overt immunological changes. by Vanessa Kurzweil (326850)

Increased DNA methyltransferase gene expression in prostate cancer cell lines was decreased with SFN or DIM treatments. by Carmen P. Wong (512550)

Fig 5 - by Zixiang Wang (7548716)

Differentially expressed mature microRNAs in CaSki cells modulated by calcitriol, with fold change thresholds of ≥ 1.5 or ≤ -1.5. by Euclides Avila (41023)

The transcript and protein abundances of several VAC-residing proteases were decreased in Δ<i>crt</i>. by L. Brock Thornton (6808385)

<i>In vivo</i> treatment with entinostat decreases Foxp3 expression in Tregs and inhibits Tregs function. by Li Shen (110858)

“…Cells were harvested from spleens and lymph nodes. A, <i>In vivo</i> entinostat treatment decreased the expression level of Foxp3 in CD4⁺Foxp3⁺ (Treg) cells. …”

Decreased expression of SMAD1/5/8 and VEFG in the Botox injected side MCC and subchondral bone. by Eliane H. Dutra (3207312)

Increase of Viral Dose and Addition of Mosquito Salivary Gland Extracts (SGE) Decrease circulating Viral RNA. by Anne M. Wertheimer (359266)

Functional analysis of trajectories: selected categories showing at least two increases and no decreases over the time course. by Weiguo Feng (256019)

<i>Becn1</i>^FA/FA mutation ameliorates cerebral Aβ accumulation, memory deficits and mortality of Alzheimer’s mouse models. by Altea Rocchi (3278457)

AMPK activators reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

“…<p>(A) Representative western blot images (upper) and summarized data (lower) showing the effects of AICAR (n = 5 for each group) (A), ASP (n = 4 for each group) (B), and MET (n = 7 for each group) (C) on DEX-induced decreases of GR and pAMPK in cultured astrocytes. …”

Exposure to glucocorticoids decreases the levels of pAMPK and GR in cultured rat prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

Functional analysis of trajectories: selected categories showing at least two decreases and no increases over the time course. by Weiguo Feng (256019)

Occupancy of Sp1 at GC1 of the topoisomerase IIα promoter decreases after doxorubicin treatment by Amram O Williams (31067)

siRNA knockdown of PP6R1 significantly decreases DNA-PK kinase activity. by Jun Mi (374600)

ELISA analysis revealed a significant decrease in SP (A & B) and CGRP (C & D) protein levels in the corneas and tear fluid of mice treated with 0.5% bupivacaine (BUP) every alternate day for 15 days (administered via subconjunctival injection (SCI) alone or in combination with topical (TOP) application) compared to PBS-treated controls. by Ananya Datta (19932144)

Fold changes in selected lung tissue mRNAs specific for mucin (Muc4, Muc5ac, and Muc5b) and Th2 cytokine (IL-4, IL-5, and Il-13) genes, after mice were fed (n-3) or (n-6) PUFA enri... by Jean A. Hall (289030)

Cre-mediated activation of RIαB allele specifically in the liver decreases PKA activity in vivo. by Brandon S. Willis (353418)

Fluoxetine decreases TOPFlash firefly luciferase reporter activity. by Kentaro Miyamoto (123271)