Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1^+/Δ) and their wild type (WT) counterparts.…”

Image_1_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1^+/Δ) and their wild type (WT) counterparts.…”

Figure S1 - Antimicrobial Resistance in Invasive Non-typhoid <em>Salmonella</em> from the Democratic Republic of the Congo: Emergence of Decreased Fluoroquinolone Susceptibility an... by Octavie Lunguya (122719)

The relationship between experimental and predicted ΔΔG of ACE2 mutants and relative SARS-CoV-2 pseudotype infectivity reported by Shukla et al [38]. by Stuart A. MacGowan (11326845)

MiR-132-3p was downregulated in TGF-<i>β</i>1 stimulated Met-5A cells and miR-132-3p mimics and miR-132-3p inhibitor transfected Met-5A cells. by Yangyang Yin (14323701)

Subjects:

Decreased adhesive potential of SNB-19 cells following mAb-blocking (a) and siRNA-KD (b) of CD44/CD155. by Zaynah Maherally (332454)

Decreased proliferation in <i>AnxA2</i>kd and <i>AnxA5</i>kd cells. by Damian C. Genetos (325684)

Effect of high-fructose (HFr) supplementation (500 μM) on markers of oxidative stress and HO-1 and SIRT1 gene expressions in hepatocytes treated with and without CoPP (5 μM) and Sn... by Komal Sodhi (540891)

Kcnk5b enhanced depolarization is required for enhanced fin bud growth. by Xiaowen Jiang (8291814)

Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 levels without altering clinical evolution of pulmonary tuberculosis or Th1/Th2/Th17 cytokine profile by João Hugo Abdalla Santos (5224121)

Non-annotated transcripts analyzed by Northern blot hybridization. by Julia Hahn (3279486)

Decreased Aβ oligomer immunoreactivity in APPxPS1 mice after treatment with hNGFP61S/R100E: scFV A13 antibody. by Simona Capsoni (161132)

Decreasing NR1 and NR2A gene expression in 5-, 14- and 21-day groups. by Chenxia Han (4020017)

The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes by Marie Neergaard Harder (232759)

“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”

Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene <i>PER2</i> expression by Kristina Hasakova (7553306)

“…<div><p>Colorectal cancer represents a leading cause of cancer death. MicroRNAs (miRNAs) are small non-coding RNA molecules that have been extensively studied in tumours, since changes in their levels can reveal patient prognosis. …”

Suction-electrode recordings from WT and <i>TrUx;GapOx</i> rods. by Ala Morshedian (4165957)

A heatmap of differentially expressed genes between the pregnant and non-pregnant sows. by Junye Shen (670568)

HDAC5 inhibitors reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

Mean probability of reporting a specific health status in non-hypertensive and hypertensive patients, with and without related medication, while excluding the effects of other fact... by Jesús Martín-Fernández (406234)

Data and code from: Continental declines in North American small mammal populations by Alec Medd (20968740)

“…To test this idea, we assembled from small mammal researchers 818 time series of small mammal abundances, containing a total of 5,317 individual abundance data points, for 66 species in 21 genera. …”