Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria by Patricia A. Reis (109310)

“…<div><p>Cerebral malaria (CM) is the most severe manifestation of <em>Plasmodium falciparum</em> infection in children and non-immune adults. Previous work has documented a persistent cognitive impairment in children who survive an episode of CM that is mimicked in animal models of the disease. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Differential expression analysis of nuclear transcripts after siAPOBEC3A depletion reveals induction of TP53 targets and decreases in cell cycle and cell growth regulator transcrip... by Mason A. McCool (11889842)

Autophagy inhibition decrease LAMP2 levels and survival of neuroendocrine differentiated LNCaP cells. by Cecilia Morell (729630)

Image_5_v1_Systemic Immune Modulation Alters Local Bone Regeneration in a Delayed Treatment Composite Model of Non-Union Extremity Trauma.jpeg by Casey E. Vantucci (10528263)

“…This overall increase correlated with a decrease in bone volume (P = 0.057) at 6 weeks post-treatment and a significant decrease in mechanical strength at 12 weeks post-treatment compared to untreated rats. …”

Inhibition of SKI-1/S1P enzymatic activity using PF-429242 impairs activation of the SREBP pathway and correlates with a dramatic decrease in lipid droplet number and area. by Anastasia Hyrina (3860455)

Decreased 5-hmC expression was associated with <i>TET2</i> downregulation. by Xuejiao Shi (1684186)

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…<p><b>A.</b> Representative traces of potassium currents evoked with 10 mV potential steps from −70mV to +60 mV in PFC PV interneurons from control (black) and cuprizone (red) mice. …”

Video_5_Why Does Child Mortality Decrease With Age? Modeling the Age-Associated Decrease in Mortality Rate Using WHO Metadata From 25 Countries.MP4 by Josef Dolejs (5534258)

“…<p>Background: Our previous study analyzed the age trajectory of mortality (ATM) in 14 European countries, while this study aimed at investigating ATM in other continents and in countries with a higher level of mortality. Data from 11 Non-European countries were used.…”

The M650K mutation decreases the firing rate of DRG neurons. by Andreas M. Kist (3106548)

Substrate translocation via Mep2^H194E induces a pH decrease. by Ana Sofia Brito (8463537)

The m⁶A peak of 3’UTR of TLR4 mRNA decreases significantly in METTL14-knockdown PK-15 cells. by Jing Chen (4762)

Mitochondrial enzyme ALAS1 interacts with MeV-V protein. by Pierre Khalfi (7868252)

Subjects:

Validation of genetic markers for risk of OA or knee OA for decrease in minJSW. by Mieke L. M. Bentvelzen (21594442)

“…<p><b>(A)</b> Manhattan plot of minJSW decrease at 24 months. …”

The T-type channel antagonist Ni²⁺ decreases adult turtle motoneuron excitability. by Martha Canto-Bustos (634777)

Overexpression of Lethe in RAW macrophage cells decreases ROS production. by Carlos Zgheib (311460)

SOD1 deficiency and the HM/LF diet produce an additive increase in endothelial dysfunction and induce a non-additive decrease in vasodilator responses to nitroprusside and papaverine. by Sanjana Dayal (630357)

Non-hydrolysable ATP analogues prevent decrease of I_Ca,L by metabolic inhibition. by Giedrius Kanaporis (4405525)

JTXK granule decreased the plasma insulin concentration, and improved insulin sensitivity in T2DM KKAy mice. by Na Yu (151735)