Large-scale analysis by SAGE reveals new mechanisms of oncogene action-4 by Corinne Bresson (73910)

“…The fold repression is represented, corresponding to a decrease of mRNA accumulation in T2ECs expressing the transforming form of v-ErbA (VA) in comparison with T2ECs expressing the non-transforming form of v-ErbA (NTVA). …”

ENMD-1198 inhibits c-Src-mediated STAT3 activation. by Saad Yousuf (541082)

“…A decrease in transcriptional activity was observed in cells **(p<0.00004) transfected with RKIP and treated with IL-6 when compared to cells treated with IL-6 (<i>bars</i>  =  mean ± S.D., of 2 experiments performed in triplicate). …”

Data_Sheet_1_Interlimb Coordination Performance in Seated Position in Persons With Multiple Sclerosis: Reduced Amplitude Over 6 min and Higher Coordination Variability in Persons W... by Mieke Goetschalckx (11585116)

“…A significant group^∗time interaction effect was found for movement amplitude, represented by a significant decrease in movement amplitude in the WF group from minute 1 to the end of the task.…”

Raising <i>Gba1b</i>^<i>-/-</i> flies under GF conditions reverses immune activation in fat body and brain tissues. by Magda L. Atilano (17020294)

“…One-way ANOVA and Tukey’s post hoc analysis; data are presented as mean ± 95% confidence intervals. <b>(B)</b> Western blot analysis reveals a decrease in Draper 1 levels in the heads of GF <i>Gba1b</i>^<i>-/-</i> flies compared to non-GF flies (n = 3; GF <i>Gba1b</i>^<i>-/-</i> vs non-GF *p = 0.045; GF controls vs non-GF p = 0.2472). …”

Exercise induced variation in intensity of the two frequency domains identified after wavelet decomposition of the thyro-hyoid muscles electrical activity during exercise. by Marta Cercone (7548236)

“…The DDSP group (red bars) showed a non-significant initial increase followed by a non-significant decrease in the intensity of both domains during exercise. …”

Testing FAA in post-natal knockout, complete null, and catalytic mutant Sirt1 mice. by Dina R. Assali (5447489)

“…CR diets began on Day 0. Mean high activity data for home cage behaviors at (B) Day -7 (n = 8 KO, n = 9 WT), (C) Day 14 (n = 9 KO and WT) of CR, and (D) Day 28 (n = 9 KO and WT) of CR are shown. …”

COMMD1 mediates aggregation of ALS-associated SOD1 mutants. by Willianne I. M. Vonk (191330)

“…<p><b>A.</b> SOD1-Flag WT and mutant (A4V, G37R, G85R, D90A, G93A, E100G) constructs were co-transfected with either EV (–) or HA-COMMD1 in HEK293T cells prior to detection of SOD1 aggregates by means of filter trap analysis on cellulose acetate membrane as described in Experimental procedures section (40 μg protein; upper panel). …”

Fig 2 - by Samara S. Souza (9600792)

“…<p>(A) Schematic design of the transplant sites with the different regions (R1, R2, R3, R4, R5, and R6) used to evaluate the local blood flow in each neck side [i.e., left side = non-cooled (25°C) transplant treatments, and right side = cooled (4°C) transplant treatments]. …”

Siah1/2-dependent gene expression analysis confirms an ER stress signature. by Marzia Scortegagna (561529)

“…Shown are representative genes of the hypoxia (panel E and F), and diabetes/metabolism (panel G and H) pathways found to exhibit increase or decrease expression upon KO of Siah1a/2. The results are shown as the mean values ± S.E. of three independent experiments. …”

Overall influence of the levels of stimulation on behavioral thresholds and latencies. by Ivanne Pincedé (270921)

“…On average, the behavioral threshold T_R was 46.7 (45.9-47.5)°C with a non-significant tendency to decrease from the proximal to the distal parts of the tail. …”

The Loss of Metabolic Control on Alcohol Drinking in Heavy Drinking Alcohol-Dependent Subjects by Philippe de Timary (152757)

“…</p> <h3>Conclusion</h3><p>For individuals consuming below12.5 kcal/kg/day of alcohol, alcohol intake is compensated for by a decrease in non-alcoholic nutrient intakes, probably due to changes in metabolic and satiety factors. …”

Swift transition from polyclonality to monoclonality in Tg8 mice is associated with further upregulated Notch. by Huizhong Xiong (502582)

“…Shown are DP-gated T cells from a case in which a Vβ6⁺ (top panel) TCL arose, with resulting decrease in the proportion of Vβ 8.1.2 (bottom panel) T cells. …”

CD4 T cell dependence of vaccine-induced protection against <i>G</i>. <i>lamblia</i>. by Sozaburo Ihara (4967050)

“…Data are compiled from two separate experiments, with mean day 5 log₁₀ trophozoite loads in the CTX controls of 6.87 and 7.31 (A, WT mice), 6.53 and 5.06 (A, CD4 KO), and 7.20 and 6.99 (B, Rag-2 KO). …”

Recapitulation of known characteristics of malaria parasite placental adhesion. by Philippe Boeuf (58228)

“…When normalized to the adhesion intensity in the absence of serum, sera from non-pregnant controls from Melbourne (Melb. CTR) did not induce any significant decrease in adhesion intensity whereas a pool of patients' sera selected for their high immunoglobulin titers against CS2 did. …”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…In purple are EPSP percent changes for 4 recorded interneurons, which show heterogeneous changes during the UP state ranging from a 30% increase to a 65% decrease (mean: 26.5% decrease, standard deviation 50.0%; see gray bar at left of graph). …”

Rat myometrial contractility changes over gestation in response to GYY4137. by Hayley Robinson (305262)

“…<p>(<b>A</b>) Representative isometric recordings of spontaneously contracting myometrial strips obtained from i) non-pregnant (NP), ii) 14 day, iii) 18 day, iv)22 day gestation and v) in labour rats before and after incubation in 1 mM GYY4137 (GYY). …”

Altered TRPV1 staining is observed in DRG obtained from STZ-induced diabetic mice by Reddy M Pabbidi (44094)

“…Summary graph showing increase in mean gray values of TRPV1 staining (n = 5 sections from 4 mice, p < 0.058) in hyperalgesic DRG and decrease in TRPV1 gray value in hypoalgesic diabetic mice (n = 6 sections from 4 mice, p < 0.05) as compared to control non-diabetic mice. . …”

GlVps depletion affects AcPh localization and activity. by Maria R. Rivero (141332)

“…Results are the means ± S.D. of 100 independent cells/group. (C) Crude protein extract from equal numbers of <i>GlVps-antisense+AcPh-V5</i> transgenic and <i>wild-type</i> (wt) trophozoites was separated by SDS–PAGE and analyzed by immunoblotting using anti-V5 mAb. …”

Endocytosis of PrP increases ferritin iron content. by Ajay Singh (227970)

“…<p>(A) PrP^C-cells exposed to 1 µg/ml of 3F4 for 5 days were radiolabeled with ⁵⁹FeCl₃ for 4 hours, and lysates were fractionated on a non-denaturing gel and auto-radiographed (lanes 1 and 2). …”

Models spontaneously develop separate modules for ‘vector-‘ and ‘transition’-based strategies. by Denis C. L. Lan (21807775)

“…Lesioning ‘vector’ units leads to a decrease in use of ‘direction’ actions and lesioning ‘transition’ units leads to a decrease in use of ‘state’ actions. …”