Gene expression-constrained iPst19 highlights the relevance of amino acid metabolism. by Philip J. Tubergen (17706003)

“…The centroids for each condition are shown as a blue circle and a red triangle. (D) Twenty most influential reactions assessed as mean decrease accuracy (as a percent) of a random forest analysis. …”

Isoform-specific Tutl overexpression differentially regulates dendrite branching in class II and III da neurons. by Mikolaj J. Sulkowski (177479)

“…Anterior is left and dorsal up and size bars represents 150 microns for ldaA and 100 microns for v'pda. (<b>A</b>) Wild-type (WT) ldaA neuron. …”

Myelin alteration in 8-week-old TRAF4-KO mice. by Sébastien Blaise (332585)

“…(C): Western blot analysis of the myelin-specific MBP marker and of the interglial-specific TJ marker claudin 11 (cl 11) showed a decreased expression level of both proteins in 4 independent TRAF4-KO cerebellum protein extracts (lanes 5–8) compared with 4 WT samples (lanes 1–4) ; tubulin served as a loading control. …”

Data_Sheet_1_Weight Change and Mortality Risk in Heart Failure With Preserved Ejection Fraction.docx by Peisen Huang (10921104)

“…Weight loss and weight gain were defined as a decrease or increase in weight ≥5% between baseline and 1 year. …”

Changes in catalase in the developing oocyte of <i>Lu. longipalpis</i>. by Hector Diaz-Albiter (227906)

“…Relative expression was statistically different in all 3, 6 and 9 days old flies (P = 0.001, ANOVA). A 4^th group (n = 15 females) fed on an ascorbic acid-supplemented sugar solution upon emergence (9-AscA) showed catalase relative expression levels similar to groups of younger flies fed on 70% sucrose solution, and statistically higher than the non-treated, 9 DPE group (P<0.002, t-test). …”

Visual motor response assay at 28 dpf. by Morgan Barnes (7876373)

“…(E-H) VMR parameters in dnVDRa induced zebrafish at 48 hpf. There is a significant decrease in distance moved in the dark period (p < 0.05), a significant decrease in velocity in the dark (p < 0.05) and light (p < 0.01) periods, a significant decrease in activity state in the dark period (p < 0.001) and light period (p < 0.01) and a significant decrease in distance to point in the dark period (p < 0.05) and light period (p < 0.05) in the 48 + fish. …”

Retrotransposon expression in <i>Pld6</i> KO and <i>Dnmt3l</i> KO spermatocytes. by Kota Inoue (4282273)

“…<p>(A) Expression of individual retrotransposons in <i>Pld6</i> KO and WT spermatocytes. …”

Internalization segregates active and inactive β₂ARs. by Tien-Hung Lan (229446)

“…<p><b>A</b>, schematic representation of recruitment of wild-type (wt) β₂AR-Rluc8 and wt β₂AR-V to coated pits and internalization (<i>left</i>), and segregation of wt β₂AR-Rluc8 and β₂AR D113S-V (<i>right</i>). …”

TBC1D24 maintains dendritic spines through suppression of ARF6. by Lianfeng Lin (8384634)

“…<p><b>(A)</b> HEK 293T cells were co-transfected with FLAG-tagged TBC1D24 plasmid together with HA-tagged ARF6 or Myc-tagged Rab35 wild-type (WT) or mutant constructs. …”

Questionnaire results and their correlation with real usage frequency. by Aviad Hadar (4225357)

“…Posthoc analysis revealed a significant increase (p = 0.034) from baseline in CAS score in the NUsp group while NUco showed a mild non- significant decrease in CAS (p = 0.15). p_corrected term refers to instances of multiple comparisons where the p value was Bonferroni corrected.…”

Alcohol Induced Alterations to the Human Fecal VOC Metabolome by Robin D. Couch (127589)

“…The most notable metabolite alterations in the alcoholic samples include: (1) an elevation in the oxidative stress biomarker tetradecane; (2) a decrease in five fatty alcohols with anti-oxidant property; (3) a decrease in the short chain fatty acids propionate and isobutyrate, important in maintaining intestinal epithelial cell health and barrier integrity; (4) a decrease in alcohol consumption natural suppressant caryophyllene; (5) a decrease in natural product and hepatic steatosis attenuator camphene; and (6) decreased dimethyl disulfide and dimethyl trisulfide, microbial products of decomposition. …”

Mutations in Rac1-Y64 changed binding to GTP. by Fumin Chang (193521)

“…<p>(A) Left panel: MEF cells were transfected with Rac1 mutants including EGFP-Rac1-61L (lane 1 EGFP-Rac1-17N (lane 2), EGFP-Rac1-Y64D (lane 3), or EGFP-Rac1-Y64F (lane 4), or with EGFP (lane 5), or EGFP-Rac1-WT (lane 6). …”

The sera obtained from the patients with t-CIDP, MADSAM and DADS disrupted the BNB. by Fumitaka Shimizu (545145)

“…<p>(A) – (D) Effects of the sera obtained from patients with three different phenotypes of chronic inflammatory demyelinating polyneuropathy (CIDP) on the protein levels of claudin-5 and occludin in the FH-BNBs, as determined using a Western blot analysis. …”

VCC-induced in vivo pro-inflammatory response and toxicity are TLR-dependent. by Shraddha Gandhi (21001590)

“…(B) Left panel shows the decrease in serum IL-6 levels in mice infected with VCC-deleted (Δ<i>hlyA</i>) <i>V. cholerae</i> variant, in comparison to those in mice infected with the wild type (WT) <i>V. cholerae</i>. …”

Inhibition of KDM expression <i>in vivo</i>. by Hanitriniaina Rabeony (596171)

“…At 24 h quantitative RT-PCR analysis was carried out on total RNA and expression levels for cytokeratin 1 (CK1), cytokeratin 10 (CK10), loricrin (LOR), filaggrin (FLG), desmoglein 1 (DSG1), desmocollin 1 (DSC1) and involucrin (IVL) were normalized using GAPDH housekeeping gene and expressed as the fold decrease under non injected skin. Data are represented as mean and SEM of 3 independent experiments. …”

Olfactory responses to ethyl acetate by TK-7 and other dsRNA treatment using single sensillum recording. by Je Won Jung (121755)

“…<p>(<b>A</b>) Saline injection caused no significant changes after injection (N=5, p>0.5). …”

Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter-6 by Stephen E Braun (84385)

Monitoring ciliary entry and exit of Smo-mEos2 in KAAD-cyclopamine-treated cells. by Jynho Kim (614435)

“…Each point shows the mean ± SEM of fluorescence from 5 cilia. (D) Quantification of Smo-mEos2^N recovery (green) and Smo-mEos2^P decrease (red) in the cilium of SAG and KAAD-cyclopamine treated cells. …”

Monitoring ciliary entry and exit of Smo-mEos2 in CBA-treated cells. by Jynho Kim (614435)

“…Each point shows the mean ± SEM of fluorescence from 5 cilia. (D) Quantification of Smo-mEos2^N recovery (green) and Smo-mEos2^P decrease (red) in the cilium of SAG and CBA treated cells. …”

Pol II, nucleosome, and H3K4me3 dynamics at circadian promoters. by Pål O. Westermark (3140802)

“…Mean H2A.Z pileups for all circadian promoters at the +1 nucleosome normalized to the +1 nucleosome peak (Methods) were ranked and divided into 5 quantiles for visualization. …”