Showing 221 - 240 results of 37,631 for search '(( a point decrease ) OR ((( 5 c decrease ) OR ( 100 ((nm decrease) OR (we decrease)) ))))', query time: 0.73s Refine Results
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    Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

    Published 2024
    “…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …”
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    Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

    Published 2024
    “…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …”
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    Fig 5 - by Ke Lu (124270)

    Published 2022
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    Pep4 overexpression decreased APCs in Vps21- and ESCRT-mutant cells after nitrogen starvation. by Zulin Wu (4451572)

    Published 2022
    “…<p><b>A.</b> The accumulation of GFP-Atg8-labeled APCs in mutant cells (<i>vps21Δ</i>, <i>snf7Δ</i>, and <i>vps4Δ</i>) slightly decreased with Pep4 overexpression. …”
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