Arginine 58 is indispensable for proper function of the <i>Francisella tularensis</i> subsp. <i>holarctica</i> FSC200 HU protein, and its substitution alters virulence and mediates... by Pavla Pavlik (13953195)

“…Finally, in order to verify biological function of the HU protein, we demonstrated that mutations in arginine 58, arginine 61, and serine 74 of the HU protein decrease virulence of FSC200 both <i>in vitro</i> and <i>in vivo</i> and that immunization using these mutant strains is able to protect as many as 100% of mice against wild-type challenge. …”

Image_1_Investigating Serum sHLA-G Cooperation With MRI Activity and Disease-Modifying Treatment Outcome in Relapsing-Remitting Multiple Sclerosis.pdf by Roberta Amoriello (8691627)

“…A significant decrease of sHLA-G was found after 24 months of NTZ in low producers carrying the +3142 C/G genotype. …”

Data_Sheet_1_Girls-Boys: An Investigation of Gender Differences in the Behavioral and Neural Mechanisms of Trust and Reciprocity in Adolescence.pdf by Imke L. J. Lemmers-Jansen (6328598)

“…</p>Methods<p>Here we investigate age-related gender differences in trust and reciprocity (n = 100, 51 female) and associated neural mechanisms (n = 44, 20 female) in adolescents between 13 and 19 years of age. …”

DataSheet1_Uptake of selected organic ligands by hardened cement paste: Studies on proxy ligands for the degradation of polyacrylonitrile and general considerations on the role of... by P. G. Szabo (13908240)

“…On the contrary, GTA induces a clear decrease in the surface charge above [GTA]_tot ≈ 10⁻³ M resulting in an isoelectric point at [GTA]_tot ≈ 6⋅10⁻² M. …”

States with <i>higher</i> minimum wages have <i>lower</i> STI rates among women: Results of an ecological study of 66 US metropolitan areas, 2003-2015 by Umedjon Ibragimov (7481078)

“…We found that a $1 increase in the price-adjusted minimum wage over time was associated with a 19.7% decrease in syphilis rates among women and with an 8.5% drop in gonorrhea rates among women. …”

DataSheet_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.docx by Jacob MacWilliams (5040044)

“…We hypothesize that insect feeding may induce changes in cannabinoids as an adaptive strategy for defense. …”

Image_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg by Jacob MacWilliams (5040044)

“…We hypothesize that insect feeding may induce changes in cannabinoids as an adaptive strategy for defense. …”

Image_2_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg by Jacob MacWilliams (5040044)

“…We hypothesize that insect feeding may induce changes in cannabinoids as an adaptive strategy for defense. …”

Image_1_Temporal dynamics of sugar beet (Beta vulgaris L.) N supply from cover crops differing in biomass quantity and composition.jpg by Heinz-Josef Koch (7057142)

“…Despite cover crop N uptake up to 170 kg N ha⁻¹ and C:N ratios < 20, a positive N effect on sugar beet was only found between March and July of the beet growing season and was 50 kg N ha⁻¹ at maximum, while between August and September, net immobilization was predominant with up to 100 kg N ha⁻¹. …”

Data_Sheet_1_Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice.PDF by Tim Ebert (11685694)

“…Subsequent biochemical analyses of hippocampal specimens by capillary immunodetection and liquid chromatography mass spectrometry-based (LC/MS) metabolomics revealed a higher abundance of glial markers (IBA-1, S100B, and GFAP) as well as distinct alterations in metabolites including a decrease in vitamins (pantothenic acid and nicotinamide), neurotransmitters (acetylcholine), their metabolites (glutamine), and acetyl-L-carnitine. …”

Data_Sheet_2_Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice.docx by Tim Ebert (11685694)

“…Subsequent biochemical analyses of hippocampal specimens by capillary immunodetection and liquid chromatography mass spectrometry-based (LC/MS) metabolomics revealed a higher abundance of glial markers (IBA-1, S100B, and GFAP) as well as distinct alterations in metabolites including a decrease in vitamins (pantothenic acid and nicotinamide), neurotransmitters (acetylcholine), their metabolites (glutamine), and acetyl-L-carnitine. …”

Data_Sheet_1_Resveratrol Alleviates the KCl Salinity Stress of Malus hupehensis Rhed.PDF by Tingting Li (10553)

“…However, its role in relation to KCl stress has never been reported. Herein we investigated the role of Res in KCl stress response of Malus hupehensis Rehd., a widely used apple rootstock in China which is sensitive to KCl stress. …”

End-Functionalization of Diarylethene for Opto-Electronic Switching with High Fatigue Resistance by Syed Zahid Hassan (7054517)

“…Furthermore, the exceptionally high DAE_C6 quantum yield enables robust fatigue resistance under repeated photoswitching with only a 30% decrease in the on/off ratio after 100 cycles. …”

Ecosystem organic carbon storage and their drivers across the drylands of China by Longwei Dong (10525061)

“…Mean annual precipitation had a strong positive effect on the spatial distributions of vegetation carbon density in both types of ecosystems. …”

Differences in iron intake during pregnancy influence in trainability response of male rat offspring by Beatriz Franco (4697788)

“…Conclusion: Our results suggested the Restriction Offspring Group showed a marked decrease in its performance parameters, which may have occurred due to iron restriction.…”

DataSheet_1_Potential Role of Macrophage Phenotypes and CCL2 in the Pathogenesis of Takayasu Arteritis.doc by Xiufang Kong (3821644)

“…Objectives<p>To investigate vascular macrophage phenotype as well as vascular and peripheral chemokine (C-C motif) ligand 2 (CCL2) expression during different stages of disease progression in patients with Takayasu Arteritis (TA).…”

Supplementary Material for: Global, Regional, and National Burden of Neonatal Encephalopathy Due to Birth Asphyxia and Trauma, Its Attributable Risk Factors, 1990-2021: Results fro... by figshare admin karger (2628495)

“…Low SDI regions experienced a substantial 112.9% increase in NEBAT cases, while high-middle SDI regions witnessed a significant 34.8% decrease. …”

Urban scaling of ICU beds, high-risk and low-risk populations. by Haroldo V. Ribeiro (9411459)

“…The behavior of these three quantities partially explains the initial decrease of number of deaths <i>per capita</i> with population (<i>β</i>_<i>d</i> < 1 for <i>t_d</i> ≲ 100 days). …”

Sambucus australis Modulates Inflammatory Response via Inhibition of Nuclear Factor Kappa B (NF-kB) in vitro by NORMA V.Q. CARNEIRO (6509828)

“…Treatment with EMSA at concentrations of 100, 50, 25 and 12.5 µg/ml significantly decreased IL-4 (p<0.001) and IL-5 (p<0.001) levels. …”

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”