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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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Advanced Hard Ctings: Towards A Whole New World
منشور في 2014"…The main problem with steel, is that it exhibits a relatively low hardness (below 10 GPa) which strongly decreases upon annealing above about 600 K. …"
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Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression
منشور في 2018"…The dietary addition of OA alone suppressed the humoral immune responses, however, the exposure of birds to 1.0 mg/kg OA in the presence of LC and/or VE showed a significant reduction in OA induced immunotoxicity. …"
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Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats.
منشور في 2020"…CsA increased blood pressure (by 46mmHg) and decreased creatinine clearance (by 49%, all P<0.05). …"
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Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
منشور في 2021"…Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. …"
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The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
منشور في 2017"…We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …"
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