GJ inhibition is the key driver of single-cell Ca²⁺ spike activity. by Dharsan K. Soundarrajan (11632145)

“…<b>(B-E)</b> <i>K</i>_<i>PLC</i> is increased left-to-right (red bar), and gap junction communication is decreased left-to-right (blue bar). An increase in <i>K</i>_<i>PLC</i> results in a decrease in frequency, while decrease in gap junction communication results in single-cell Ca²⁺ spikes (red arrows).…”

Land-use changes affect the functional structure of stream fish assemblages in the Brazilian Savanna by Ludmilla R. P. Alvarenga (12682514)

Endovascular revascularization of TASC C and D femoropopliteal occlusive disease using carbon dioxide as contrast by Cynthia de Almeida Mendes (10407739)

Distribution of differences of DNA methylation between normal mammary glands and mammary carcinomas. by Masaru Takabatake (3202710)

“…The curve shows a simulated normal distribution (mean = 0, standard deviation = 2.5) with the same spread as the data, but centered on zero to indicate the null hypothesis of no global trend. …”

NPB304 affected P-gp function and increased paclitaxel accumulation in P-gp-overexpressing resistant cells and tumor tissue. by Mei Mei (610571)

“…The data represent the mean ± SD. *p<0.05, **p<0.01. (C) NPB304 treatment promoted bidirectional permeability but decreased the efflux ratio of paclitaxel in a Caco-2 monolayer model. …”

Passive listening and go/No-go tasks feature comparable electrophysiological responses. by Sarah H. McGill (22505225)

“…<p>The differences between the mean peristimulus spectrograms of maximum-intensity auditory stimulus trials (65.7 dB) and no-stimulus trials (63.5 dB white noise only) are shown here for passive listening (left) and go/no-go (right tasks). …”

Clinical and epidemiological profile of patients with hypertensive peak after Ahmed glaucoma valve implant by Flávia da Silva Vilas-Boas (5910116)

“…After 6 months of follow-up the mean IOP decreased (16.4 ± 6.74 mmHg), with 2.23 ± 1.45 medications. …”

VpsO-503 does not undergo tyrosine trans autophosphorylation <i>in vitro</i>. by Carmen Schwechheimer (9300303)

“…<p><b>(A)</b> [γ-³²P]-ATP kinase assay as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008745#ppat.1008745.g005" target="_blank">Fig 5E</a>. …”

The effect of mutation rate variation. by Thomas Mailund (51584)

“…We split the alignment into segments geometrically distributed with mean length 500 bp and 2 kbp, and the mutation rate is then scaled by a random value chosen uniformly in the range 0.75 to 1.25 or 0.5 to 1.5. …”

Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

<i>Drosophila</i> peroxisomal gene networks. by Michael F. Wangler (544124)

“…These <i>Drosophila</i> peroxisomal genes are clustered in 5 co-regulated gene clusters that were subsequently used to identify the top 1000 genes for each cluster that has a similar expression pattern from <i>Drosophila</i> gene expression data-sets. …”

Aerofoil Design for Unmanned High-Altitude Aft-Swept Flying Wings by Ahmad Abdulkarim Alsahlan (4659976)

“…The second part contains the optimisation code using a genetic algorithm. The primary target here was to design a number of aerofoils with low pitching moment, suitable for an aft-swept flying wing configuration operating at low Reynolds number in the range of about 0.5 × 106. …”

SCS Designs 6, 7, and 8. by Matthew R. Lakin (649454)

“…We tested various lengths for the substrate binding arms of the upstream DNAzyme (denoted as 5′/3′ in the Figure). These results showed that longer substrate binding arms decrease the effect on activation rate by reducing the rate of product dissociation. …”

The NH₂-terminus of PDX-1 binds to <i>Krt19</i> promoter DNA. by Johannes von Burstin (243524)

“…C) MIN6 cells were transfected with V5-tagged full length PDX-1 or PDX-1 Δ1-37. DNA precipitation was carried out as described above, and membranes were probed with anti-V5. …”

siRNA screening system to identify regulators of insulin promoter activity. by Gregory M. Ku (188067)

“…If the siRNA targets a positive regulator, GFP/mCherry MFI decreases. …”

Induced Wnt signaling post-SE coordinates AMPK and mTOR signaling pathways. by Roaya S. Alqurashi (11243136)

“…(n = 3–5 for each group). Data are represented as mean ± SEM. …”

Data_Sheet_1_SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine.doc by Lin-nan Zhu (5681939)

“…Levels of the ubiquitin-proteasome system (UPS)-related makers ubiquitin (Ub) and UbE1, as well as the autophagy-lysosome pathway (ALP)-related markers LC3, P62 and lysosomal associated membrane protein 2A (LAMP2A), were also measured in SH-SY5Y cells transfected with lentivirus and mice injected with adenovirus. …”

Image_2_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP) by Jamileh Hashemi (131207)

“…Using Nexus software analysis we combined the array-CGH data with data from gene expression profilings and identified genes that were altered in both inputs. A subset of genes identified as downregulated (<em>ALDH1A3</em>, <em>ANXA1</em>, <em>TLR4</em> and <em>RAB5A</em>) or upregulated (<em>COX6A1</em>, <em>NFIX</em>, <em>ME1</em>, <em>MAPK</em> and <em>TAP2</em>) were validated by siRNA in the tolerant or parental cells to alter sensitivity to PPP and confirmed to alter sensitivity to PPP in further cell lines.…”

Metabolomics raw data and table of extracted peak areas for BT478, BT530 and NHA cells cultured in the presence of MPA, Compound 3 (IC80) or vehicle control, for 6 hours. by Agata Monika Kieliszek (14650298)

“…The linear gradient employed was as follows: 0–2.5 min 99% A, 2.5–7.5 min decrease to 80% A, 7.5–13 min to 55% B 652 and finally 13–15 min to 99% B and held for 1 min. …”