Image1_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.JPEG by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

Effects of rs10052957 (Tth111l) and rs6190 (R23K) genotypes on GR mRNA expression. by Duncan Sinclair (329606)

“…<p>A) A significant main effect of rs10052957 genotype on GR-1B mRNA expression was identified (ANCOVA F(2, 81) = 5.32, <i>p</i><0.001), with significant decreases in GR-1B expression in individuals with CC genotype (n = 46) relative to those with TC genotype (n = 40; 18.4% decrease, <i>p</i><0.05) and TT genotype (n = 9; 31.8% decrease, <i>p</i><0.005). …”

cLTP-induced DA-actin exodus is blocked by an inhibitor of myosin II ATPase. by Toshiyuki Mizui (513144)

“…The aBL-treated neurons did not show a decrease in the drebrin and actin SDRs at either 5 min or 30 min after cLTP stimulation (n = 30 cells; Student's test), whereas iBL-treated neurons showed a significant decrease in the drebrin and actin SDRs at 5 min (n = 30 cells; p<0.01, Scheffe's test), similar to that observed in control neurons in Fig. 3. …”

Effects of Shenfu injection on shivering prevention and hemodynamic impact in elderly patients underwent transurethral resection of the prostate by Weiqi KE (10464517)

“…Patients in the experiment group had lower incidence of shivering (10% in the experiment group versus 27.5% in the control group, p = 0.042). On average, patients in the experiment group had significantly more stable hemodynamic parameters: with lower heart rate, less decrease in systolic and diastolic blood pressure (p < 0.05 for all). …”

<i>T</i>. <i>gondii</i> myosin H is associated with three myosin light chains. by Arnault Graindorge (84051)

“…<p>(A) Endogenously tagged myosin light chains (MLC) 3, 5 and 7 localized to the conoid. …”

Presentation_1_Environmental Concentrations of Sulfonamides Can Alter Bacterial Structure and Induce Diatom Deformities in Freshwater Biofilm Communities.pdf by Laura Kergoat (10761429)

“…Sulfonamides are known to inhibit bacterial growth by altering microbial production of folic acid, but sub-lethal doses may trigger antimicrobial resistance, with unknown consequences for exposed microbial communities. We investigated the effects of two environmentally relevant concentrations (500 and 5,000 ng L^–1) of SMZ and SMX on microbial activity and structure of periphytic biofilms in stream mesocosms for 28 days. …”

Data_Sheet_1_Associations of Serum Uromodulin and Its Genetic Variants With Blood Pressure and Hypertension in Chinese Adults.docx by Yang Wang (5921)

“…Furthermore, serum uromodulin levels in the hypertensive subjects were lower than in the normotensive subjects (25.5 ± 1.1 vs. 34.7 ± 0.7 ng/mL). Serum uromodulin levels decreased gradually as BP levels increased (34.6, 33.2, 27.8, and 25.0 ng/mL for subjects with normotension, high-normal, grade 1 hypertension, and grade 2 hypertension, respectively). …”

Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction by Enise Bagci (719720)

The Strong <i>In Vivo</i> Anti-Tumor Effect of the UIC2 Monoclonal Antibody Is the Combined Result of Pgp Inhibition and Antibody Dependent Cell-Mediated Cytotoxicity by Gábor Szalóki (631712)

“…In xenotransplanted severe combined immunodeficient (SCID) mice co-treated with DOX, UIC2 and CsA, the average weight of Pgp⁺ tumors was only ∼10% of the untreated control and in 52% of these animals we could not detect tumors at all, while DOX treatment alone did not decrease the weight of Pgp⁺ tumors. …”

Table_1_Impulsive choice in two different rat models of ADHD—Spontaneously hypertensive and Lphn3 knockout rats.DOCX by Monica S. Carbajal (14506454)

Complex interactions of temperature, light and tissue damage on seagrass wasting disease in Zostera marina by Stina Jakobsson-Thor (9353879)

Assessment of <i>LINC-PINT</i> genetic polymorphisms and esophageal squamous cell carcinoma risk in the Hainan Han population by Ruisha Tu (17538040)

Comparative growth rates of cultured marine dinoflagellates in the genus <i>Symbiodinium</i> and the effects of temperature and light by Anke Klueter (365228)

“…Yet knowledge of growth kinetics of these endosymbionts and their ecological and evolutionary implications is limited. We used a Bayesian biphasic generalized logistic model to estimate key parameters of the growth of five strains of cultured <i>Symbiodinium</i>, <i>S</i>. …”

sNAG treatment reduces bacterial infection in an Akt1 dependent manner. by Haley Buff Lindner (352313)

“…Infected wounds that were treated with peptide show a significant decrease (p<.05) in CFU. Scale bars = 50 µm. …”

Multicomponent System of NPS-1034, an Orally Administered Lung Cancer Drug Candidate, with Sulfonic Acids and Solid State Characterization by Jangmi Lee (1875595)

“…However, NPS-1034 is practically insoluble in almost all organic solvents as well as aqueous media (pH 1, 4.5, and 7.5). We attempted to improve the physicochemical properties of NPS-1034 by forming multicomponent systems with a wide variety of sulfonic acids including methanesulfonic acid, 1,2-ethanedisulfonic acid, <i>p</i>-toluenesulfonic acid, and camphorsulfonic acid. …”

Multicomponent System of NPS-1034, an Orally Administered Lung Cancer Drug Candidate, with Sulfonic Acids and Solid State Characterization by Jangmi Lee (1875595)

“…However, NPS-1034 is practically insoluble in almost all organic solvents as well as aqueous media (pH 1, 4.5, and 7.5). We attempted to improve the physicochemical properties of NPS-1034 by forming multicomponent systems with a wide variety of sulfonic acids including methanesulfonic acid, 1,2-ethanedisulfonic acid, <i>p</i>-toluenesulfonic acid, and camphorsulfonic acid. …”

Multicomponent System of NPS-1034, an Orally Administered Lung Cancer Drug Candidate, with Sulfonic Acids and Solid State Characterization by Jangmi Lee (1875595)

“…However, NPS-1034 is practically insoluble in almost all organic solvents as well as aqueous media (pH 1, 4.5, and 7.5). We attempted to improve the physicochemical properties of NPS-1034 by forming multicomponent systems with a wide variety of sulfonic acids including methanesulfonic acid, 1,2-ethanedisulfonic acid, <i>p</i>-toluenesulfonic acid, and camphorsulfonic acid. …”

Multicomponent System of NPS-1034, an Orally Administered Lung Cancer Drug Candidate, with Sulfonic Acids and Solid State Characterization by Jangmi Lee (1875595)

“…However, NPS-1034 is practically insoluble in almost all organic solvents as well as aqueous media (pH 1, 4.5, and 7.5). We attempted to improve the physicochemical properties of NPS-1034 by forming multicomponent systems with a wide variety of sulfonic acids including methanesulfonic acid, 1,2-ethanedisulfonic acid, <i>p</i>-toluenesulfonic acid, and camphorsulfonic acid. …”

Multicomponent System of NPS-1034, an Orally Administered Lung Cancer Drug Candidate, with Sulfonic Acids and Solid State Characterization by Jangmi Lee (1875595)

“…However, NPS-1034 is practically insoluble in almost all organic solvents as well as aqueous media (pH 1, 4.5, and 7.5). We attempted to improve the physicochemical properties of NPS-1034 by forming multicomponent systems with a wide variety of sulfonic acids including methanesulfonic acid, 1,2-ethanedisulfonic acid, <i>p</i>-toluenesulfonic acid, and camphorsulfonic acid. …”

Figure 2. Deletion of Arrb1 attenuates the VEGF-C/VEGFR3 signaling in mice exposed to hypoxia. by Zhiyuan Ma (6441500)

“…<i>Vegfc</i> expression is pointed by a red arrow. (<b>b</b>) Decreased mRNA expression by RNA-seq of <i>Vegfc</i>, <i>Lyve1 </i>and <i>vwf</i> in the lung of <i>Arrb1</i> KO compared to WT mice exposed to hypoxia. …”