Image_2_Impact of in-utero exposure to HIV and latent TB on infant humoral responses.jpeg by Kimberly J. S. Hjelmar (18890608)

“…To address this question, we assessed the relationship between maternal humoral responses in pregnant women with HIV or with HIV/LTBI on humoral responses in infants to BCG vaccination and TB acquisition.…”

Table1_Effect of alemtuzumab over sNfL and sGFAP levels in multiple sclerosis.docx by Raquel Sainz-Amo (17279806)

“…The data indicates that 80% of patients had high (≥10 pg/ml) sNfL values at baseline. We observed a significant decrease in sNfL levels at 6 (65%, p = 0.02), 12 (70.8%, p<0.001), and 24 (78.1%, p<0.001) months. sNfL reached similar levels to HC only after 24 months of Alemtuzumab treatment. …”

Image_1_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Image_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG by Yamina El Hamdaoui (6759080)

“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”

Image_2_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Data_Sheet_1_Uric Acid Predicts Recovery of Left Ventricular Function and Adverse Events in Heart Failure With Reduced Ejection Fraction: Potential Mechanistic Insight From Network... by Xiqiang Wang (5955647)

“…Background and Aims<p>Heart failure with reduced ejection fraction (HFrEF) still carries a high risk for a sustained decrease in left ventricular ejection fraction (LVEF) even with the optimal medical therapy. …”

Image_1_Uric Acid Predicts Recovery of Left Ventricular Function and Adverse Events in Heart Failure With Reduced Ejection Fraction: Potential Mechanistic Insight From Network Anal... by Xiqiang Wang (5955647)

“…Background and Aims<p>Heart failure with reduced ejection fraction (HFrEF) still carries a high risk for a sustained decrease in left ventricular ejection fraction (LVEF) even with the optimal medical therapy. …”

Combined Red Clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms by Max Norman Tandrup Lambert (4093156)

“…Effective treatments against VMS with minimal cancer risks are needed. We investigate the effects of a highly bioavailable aglycone rich Red Clover isoflavone treatment to alleviate existing menopausal VMS, assessed for the first time by 24hour ambulatory skin conductance (SC)</p><p>Methods and results</p><p>We conducted a parallel, double blind, randomised control trial of 62 peri-menopausal women aged 40–65, reporting ≥ 5 hot flushes/day and follicle stimulating hormone ≥35 IU/L. …”

Image_1_Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice.pdf by Mark M. Smits (9242563)

“…GLP-1 secretion from GLUTag cells was unchanged after five minutes of exposure to I3A. However, GLP-1 levels increased after 120 minutes of exposure to 1 mM (60% increase, p=0.016) and 5 mM (89% increase, p=0.0025) I3A. …”

Image_3_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG by Yamina El Hamdaoui (6759080)

“…Interestingly, in the case of the α7 nAChR, but not the α3β2 subtype, the loss of potency could be rescued by an R5D substitution. In conclusion, we demonstrate efficient expression of functional but alternatively folded ribbon TxIA variants in E. coli and provide the first structure–function analysis for a ribbon 4/7-α-conotoxin at α7 and α3β2 nAChRs. …”

Image_3_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Pulmonary and Cardiac Function in Asymptomatic Obese Subjects and Changes following a Structured Weight Reduction Program: A Prospective Observational Study by Matthias Held (631393)

“…</p><p>Results</p><p>74 subjects (32 male, 42 female; mean age 42±12 years) with an average BMI 42.5±7.9, body weight 123.7±24.9 kg were enrolled. …”

Thyroid hormone (T₃) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy by Winifred W. Yau (5744939)

“…We next generated an <i>Atg5</i> conditional knockout mouse model (<i>Atg5</i> cKO) by injecting <i>Ucp1</i> promoter-driven <i>Cre</i>-expressing adenovirus into <i>Atg5</i>^Flox/Flox mice to examine effects of BAT-specific autophagy on thermogenesis <i>in vivo</i>. …”

Photoconversion of mEOS. by Suzie Dufour (383964)

“…<p>A–B) Images at different time points of a mEOS2 expressing cell during UV-induced photoconversion. …”

Fbxw8 is essential for morphogenesis of the Golgi apparatus in neurons. by Nadia Litterman (221903)

“…<p>(A) Granule neurons transfected at DIV2 with the U6/fbxw8-1, U6/fbxw8-2, or control U6 RNAi plasmid together with the GFP expression plasmid were fixed at DIV5 and were subjected to immunocytochemistry with the GFP and GM130 antibodies. …”

<b>Regulatory roles of IGF2R in insulin secretion and adaptive β-cell proliferation</b> by Jun Shirakawa (414869)

“…A β-cell line with a stable knockdown of IGF2R (IGF2RKD), exhibited decreased glucose-induced insulin secretion, and enhanced cell proliferation. …”

Functional connectivity revealed by rsfcMRI. by Corinna M. Bauer (3854026)

“…While patterns of increases and decreases in functional connectivity were evident, the overall trend was for a decrease in resting state temporal correlations in early blind compared to sighted controls. …”

Image_4_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…Of the 71 patients, 52 (73%) had decreased RV systolic function; 12 (16.9%), 26 (36.6%), and 33 (46.5%) patients had normal RV diastolic pattern, abnormal relaxation (stage 1), and pseudo-normal patterns (stage 2), respectively. …”

Image_2_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…Of the 71 patients, 52 (73%) had decreased RV systolic function; 12 (16.9%), 26 (36.6%), and 33 (46.5%) patients had normal RV diastolic pattern, abnormal relaxation (stage 1), and pseudo-normal patterns (stage 2), respectively. …”

Image_7_Right Ventricular Diastolic Performance in Patients With Chronic Thromboembolic Pulmonary Hypertension Assessed by Echocardiography.JPEG by Hong Meng (82691)

“…Of the 71 patients, 52 (73%) had decreased RV systolic function; 12 (16.9%), 26 (36.6%), and 33 (46.5%) patients had normal RV diastolic pattern, abnormal relaxation (stage 1), and pseudo-normal patterns (stage 2), respectively. …”