Rapamycin suppression of mTORC1-S6K was associated with lower cytokine levels. by Po-Shun Lee (358563)

“…Statistical analysis was performed using Repeated Measures ANOVA, and p values<0.05 are considered as significant (*). mTORC1-S6K suppression by rapamycin led to decreased circulation levels of IL1-β, VEGF, IFN-γ and IL-5. …”

Initial responses to dark-light shift compared to light intensity shift. by Marianne Nymark (257796)

“…<p>Molecular, metabolic and physiological responses after a shift from prolonged darkness (D48) to white light (WL 0.5 h; 100 µmol m⁻² s⁻¹) compared to a shift from low light (LL 0.5 h; 35 µmol m⁻² s⁻¹) to high light (HL 0.5 h; 500 µmol m⁻² s⁻¹) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058722#pone.0058722-Nymark1" target="_blank">[28]</a>.…”

Figure S1 - Antiviral and Neuroprotective Role of Octaguanidinium Dendrimer-Conjugated Morpholino Oligomers in Japanese Encephalitis by Arshed Nazmi (215284)

“…<p>MO treatments decrease viral load <i>in vitro</i>. Mouse neuroblastoma cell (N2a) lysates from all the treatment groups were subjected to plaque assay in order to determine viral loads. …”

No effect of PTL on pure primary mouse motor neuron cultures. by Nadine Thau-Habermann (457942)

“…<p>MEA measurements showed that there were no significant differences between the individual wells of plated motor neurons before treatment After 24 and 48 hours, only the LPS+PTL 5 µ M group showed a significant decrease in resistance (A) and in firing rate (B), while all other conditions showed no significant differences between each other. …”

Effects of topical application of S32826 on the rabbit cornea. by Padma Iyer (141117)

“…Topical effects of S32826 on rabbit corneal histology. Rabbits treated with a topical dose of 5 mM S32826 for 5 days (single daily dose) and which showed a decrease in IOP were enucleated and examined for corneal histological changes relative to sham treated specimens. …”

Autocrine modulation of macropinocytosis by XS52 cells via formation and release of S1P. by Lukasz Japtok (299762)

“…<p>XS52 cells were cultivated in the presence or absence of MK-571 (15 µM) and K6PC-5 (10 µM) over a time period of 6 h and S1P levels in the extracellular environment was detected (A). …”

GPN and vacuolin-1 inhibit C6 glioma cell migration in scratch assay. by Yu Liu (6938)

“…Movement of cells into the scarred region resulted in a decrease in the surface area of the scar. B. …”

Binding of NheB to Vero cells. by Uta Heilkenbrinker (408526)

“…<p>(A) Decrease of NheB binding to Vero cells as determined by flow cytometry. …”

Unrestrained Rac 1 activation in pRb-expressing osteoblasts mimics pRb loss by perturbing cell adhesion. by Bernadette Sosa-García (237746)

“…<p>Phase contrast photomicrographs at x10 (<b>A</b>) and growth curves (<b>B</b>) showing that pRb-expressing MC3T3 osteoblasts stably expressing RacV12 or dnCdk5 grow in culture to a higher density relative to pRb-expressing MC3T3 osteoblasts transfected with control vector (CV). …”

Differential expression of microRNA-411 and 376c is associated with hypertension in pregnancy by Hui-li Yang (6572189)

IL-6 promotes RKIP and STAT 3 transcription and phosphorylation; <i>H. pylori</i> infection induces STAT3 transcription and phosphorylation. by Erika L. Moen (162280)

“…For RKIP expression, our results indicate a 0.8 fold incerase of pRKIP (average intensity 0.69 vs 0.563) in cells treated with 25 ng/ml IL-6 and a 1.05 fold increase (average intensity 0.69 vs 0.745) in cells treated with 50 ng/ml IL-6 when normalized to actin at each time point. …”

Data_Sheet_1_Machine Learning-Based Systems for the Anticipation of Adverse Events After Pediatric Cardiac Surgery.docx by Patricia Garcia-Canadilla (577137)

“…However, EWS are based on measurements performed at a single time point without incorporating trends nor providing information about patient's risk trajectory. …”

Table 1_Association between dietary fiber intake and obesity in US adults: from NHANES 1999–2018.docx by Siran Lai (21668141)

“…The RCS analysis conspicuously showed a non-linear U-shaped association between dietary fiber intake and all-cause mortality (p < 0.05), with 26.3 g/day being the turning point. …”

π Donation and Its Effects on the Excited-State Lifetimes of Luminescent Platinum(II) Terpyridine Complexes in Solution by Lauren M. Hight (1929493)

“…The excited-state lifetime increases when the change in orbital parentage lowers the emission energy, suppresses quenching via d–d states, and encourages delocalization of the excitation onto the ligand(s). At some point, however, the energy is low enough that direct vibronic coupling to the ground-state surface becomes important, and the lifetime begins to decrease again.…”

Positional dependence of the probe intensities. by Hans Binder (128524)

“…<p>Panel a: Single base data of allele-specific (S-mode) PM and MM probes. …”

Data Sheet 1_Association between dietary fiber intake and obesity in US adults: from NHANES 1999–2018.pdf by Siran Lai (21668141)

“…The RCS analysis conspicuously showed a non-linear U-shaped association between dietary fiber intake and all-cause mortality (p < 0.05), with 26.3 g/day being the turning point. …”

NGF- and bFGF-stimulated prolonged ERK activation is attenuated by RGS14 knockdown. by Francis S. Willard (59137)

“…Twenty four hours later, cells were stimulated with (A) NGF (100 ng/ml) or (B) bFGF (100 ng/ml). At indicated time points, cells were lysed and then subsequently analyzed by immunoblot for both phosphorylated, activated ERK1/2 (pERK) and total ERK1/2. …”

Data_Sheet_1_Association between platelet-lymphocyte ratio and 90-day mortality in patients with intracerebral hemorrhage: data from the MIMIC-III database.PDF by Min Yuan (202757)

“…</p>Conclusion<p>There was a non-linear relationship between PLR and 90-day mortality for patients with ICH, with an inflection point at 145.54 and a minimal risk at 120.9 to <189.8 of PLR.…”

Temporal Analysis of Genomic Features in <i>Neisseria gonorrhoeae</i> Across Sequence Types. by Elaheh Ebrahimi (20371357)

“…Each data point represents a unique ST, with color variations distinguishing different STs. …”

Data_Sheet_1_Fast Changes in the Bioenergetic Balance of Krill in Response to Environmental Stress.docx by Paulo F. Lagos (12005000)

“…Environmental variability can alter the metabolic equilibrium and the mechanisms marine ectotherms used to obtain energy, which is a topical point given the current level of environmental change. …”