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The 2lox Lsd1 variant shows decreased binding to known interactors.
Published 2013“…For the two single point mutants, the M448V mutation has a more profound effect on CoREST binding. *: immunoglobulin heavy chain. …”
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448
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449
Table_1_A phased intervention bundle to decrease the mortality of patients with extracorporeal membrane oxygenation in intensive care unit.pdf
Published 2022“…In multivariable analysis, even after excluding the confounding factors, such as age, APECHII score, pre-ECMO lactate, and incidence of CRRT during ECMO, the intervention bundle still can decrease the mortality independently, which also remained true in the statistical analysis of V-V and V-A ECMO separately. …”
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450
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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451
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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452
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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453
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”
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454
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Deletion of STX1B decreases the size of RRP in glutamatergic and GABAergic synapses.
Published 2014“…<p>(A) Average EPSC evoked by application of 0.5 M hypertonic sucrose solution for 15 s in WT and STX1B<sup>−/−</sup> neurons (left). …”
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456
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Treatment with anti-JAM-C antibody decreases the severity of antigen-induced arthritis
Published 2011“…Results shown represent the mean ± SEM for anti-JAM-C antibody-treated (= 5 on day 4, = 6 on day 8, black columns) and isotype-matched control antibody-treated (= 5 at both time points, open columns) mice. …”
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458
PIN1 silencing leads to decreases in the protein levels of HIF-1α.
Published 2016“…E) ATRA decreases the expression of HIF-1α and PIN1 in HCT116/5xHRE-ODD-luc cells in dose-dependent manner. …”
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