Protein synthesis inhibition and EF-2 ADP-ribosylation in KLM-1-R. by Kevin Hollevoet (710450)

“…<p><b>A</b>: Protein synthesis inhibition by RG7787 is limited in resistant KLM-1 (KLM-1-R). …”

Table_1_Pediatric glioblastoma cells are sensitive to drugs that inhibit eIF2α dephosphorylation and its phosphomimetic S51D variant.docx by Karin Eytan (13444422)

“…Our results indicate that combinations of histone deacetylase inhibitors and PARP-1 inhibitors should be evaluated for their toxicity and efficacy in PED-GBM patients and point to drugs that increase P-eIF2α or modulate its downstream effectors as a novel means of treating PED-GBM.…”

Table 1_Joint association of sleep patterns and oxidative balance score with all-cause and cardiovascular mortality among the general population.docx by Chen Chen (6544)

“…</p>Results<p>Poor sleep patterns and pro-oxidant OBS (Q1 & Q2) were identified as risk factors for mortality. Each point increase in OBS was associated with a 3% decrease in both all-cause mortality and CVD mortality. …”

Data_Sheet_1_Qin-Qiao-Xiao-Du formula alleviate influenza virus infectious pneumonia through regulation gut microbiota and metabolomics.pdf by Bo Lian (2009434)

“…<p>Qin-Qiao-Xiao-Du (QQXD), a traditional Chinese medicine (TCM) formula, has been used in the clinical treatment of influenza virus pneumonia. …”

DataSheet_1_Pediatric glioblastoma cells are sensitive to drugs that inhibit eIF2α dephosphorylation and its phosphomimetic S51D variant.pdf by Karin Eytan (13444422)

“…Our results indicate that combinations of histone deacetylase inhibitors and PARP-1 inhibitors should be evaluated for their toxicity and efficacy in PED-GBM patients and point to drugs that increase P-eIF2α or modulate its downstream effectors as a novel means of treating PED-GBM.…”

Table_1_Selective Recording of Tectonic Forcings in an Oligocene/Miocene Submarine Channel System: Insights From New Age Constraints and Sediment Volumes From the Austrian Northern... by Julian Hülscher (8054663)

“…The visco-elastic relaxation of the European Plate results in low SARs on the overbanks [186 (t/m²/Ma)], a decrease in sediment grain size in channel deposits and a decrease in sea level at the BHU (19.6–19.0 Ma). …”

Table_2_Selective Recording of Tectonic Forcings in an Oligocene/Miocene Submarine Channel System: Insights From New Age Constraints and Sediment Volumes From the Austrian Northern... by Julian Hülscher (8054663)

“…The visco-elastic relaxation of the European Plate results in low SARs on the overbanks [186 (t/m²/Ma)], a decrease in sediment grain size in channel deposits and a decrease in sea level at the BHU (19.6–19.0 Ma). …”

Table_3_Selective Recording of Tectonic Forcings in an Oligocene/Miocene Submarine Channel System: Insights From New Age Constraints and Sediment Volumes From the Austrian Northern... by Julian Hülscher (8054663)

“…The visco-elastic relaxation of the European Plate results in low SARs on the overbanks [186 (t/m²/Ma)], a decrease in sediment grain size in channel deposits and a decrease in sea level at the BHU (19.6–19.0 Ma). …”

Data_Sheet_1_Selective Recording of Tectonic Forcings in an Oligocene/Miocene Submarine Channel System: Insights From New Age Constraints and Sediment Volumes From the Austrian Nor... by Julian Hülscher (8054663)

“…The visco-elastic relaxation of the European Plate results in low SARs on the overbanks [186 (t/m²/Ma)], a decrease in sediment grain size in channel deposits and a decrease in sea level at the BHU (19.6–19.0 Ma). …”

QRT-PCR for 27-hydroxylase and ABCA1 message in NS398-treated THP-1 macrophages exposed to prostaglandins or TXA by Edwin SL Chan (28334)

“…THP-1 human macrophages were exposed to the following conditions represented by the five bars (from left to right): (1) RPMI 1640, (2) NS398 (50 μM), (3) PGE(0.1 μM) + NS398 (50 μM), (4) PGD(14 μM) + NS398 (50 μM), and (5) TXA(3 μM) + NS398 (50 μM) (24-hour exposures to NS398 alone followed by addition of indicated PG or TXAfor a further 24 hours). …”

Increased secretion of cystatin in response to exercise is transient. by Marcelo de Lima Sant’Anna (7542707)

“…Sprints at 65%, 75% and 85% following first sample are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0224147#pone.0224147.g004" target="_blank">Fig 4</a>. # indicates a significant increase compared to total protein at rest (<i>pre</i>)(p = 0.012, n = 12). * indicates a significant increase of type-S cystatin at 5 min and § a significant decrease at 10 min compared to resting value (p = 0.012, n = 12). …”

Image_2_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Image_1_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Image_3_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Data_Sheet_1_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent St... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Image_4_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway by Alexandra V. Finsen (193861)

“…Cardiomyocytes from syndecan-4^−/−-NFAT-luciferase reporter mice subjected to cyclic mechanical stretch, a hypertrophic stimulus, showed minimal activation of NFAT (1.6-fold) compared to 5.8-fold increase in NFAT-luciferase control cardiomyocytes. …”

Table 1_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Table 2_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Effects of PD-0332991 on BSG cell lines derived from genetically engineered mouse models. by Kelly L. Barton (465812)

“…<p>Cells were treated with PD-0332991 for 48 hours before being harvested for MTT or BrdU assays to assess cell survival and proliferation, respectively. (A) MTT assays (left panel) show minimal cytotoxic activity at doses up to 5µM in cell lines derived from PDGF-B; Ink4a-ARF deficient BSGs. …”