Schematic representation of voxel-wise age- and symptom severity- related models. by Juergen Dukart (283449)

“…The hinge in the red line (aging in AD) at the intersection point indicates that after the intersection age, according to our assumption of the additive impact of AD related processes to healthy aging, the healthy aging model would apply in AD patients as no pathological processes in terms of atrophy or glucose hypometabolism are longer observable after this time point. c) Decrease (in %) in GM volume observed in an exemplary voxel in AD depending on the constellation of age and symptom severity (MMSE) relative to the baseline provided by healthy aging (violet line). …”

Podocyte injury and activation of the mTOR-ULK1 pathway. by Lingling Wu (411099)

“…PAN-treated podocytes showed an increase in ULK1 phosphorylation, a decrease in LC3 II expression, and a decrease in cellular GFP-LC3 granular expression (green fluorescence), indicating the inhibition of autophagy.…”

Characteristics of first responder cells. by Vira Kravets (11718439)

“…(<b>M</b>) Percent of the original first responders that remain among the earliest responders after adjustment of the spatial position of the first responders in 3 separate distributions (spheres) (<i>n</i> = 5 seeds). (<b>N</b>) Decrease in the AUC of the first phase of the Ca²⁺ response following de-coupling (removal) of a given % of the first responder or a random set of cells from the islet (<i>n</i> = 5 seeds). …”

Processed_Model_Data.zip by Mahdi Mahdavi (10916064)

“…<p>Early prediction of patient mortality risks during a pandemic can decrease mortality by assuring efficient resource allocation and treatment planning. …”

Supplementary Material for: Volitional Yoga Breathing Influences Attention and Anxiety: An Exploratory Randomized Crossover Study by Sharma S.K. (11713172)

“…There was a significant main effect of sessions (<i>F</i>_5,407 = 3.043, <i>p</i> = 0.010) on STAI-s scores, with scores post alternate nostril yoga breathing significantly lower than post breath awareness (<i>p</i>_<i>adj</i> = 0.037). …”

Efficiency of the municipalities of Mato Grosso do Sul State: an approach based in deterministic frontier by Antônio Carlos Cantero Dorsa (7233158)

“…From these results, we cannot say that a higher level of efficiency can lead to an increase or decrease in the Firjan Development Index, concluding that there is inefficiency in the management of public resources, and these do not guarantee results in improving income, longevity, and education of Mato Grosso do Sul.…”

<i>In silico</i> saturation mutagenesis and thermodynamic stability of MSH2 mutants. by Sofie V. Nielsen (3934307)

Excess risk of all-cause mortality attributed to the BMI not explained by the baseline comorbidities (residual risk) after adjusting for baseline mortality risk. by Jia Li (160557)

“…The dots represent the point estimates of the mortality rate in the 200 bootstrap iterations, circles are the mean, the solid line is a smooth curve representing the averages and the dashed lines are the 95% empirical confidence interval. …”

Task-evoked activity quenches neural correlations by altering the underlying attractor dynamics. by Takuya Ito (57473)

“…<b>c)</b> We injected a fixed input stimulation, shifting the network to an ‘evoked’ state, which caused a decrease in neural variability and correlation. …”

Staircase trace example. by Xiao Ling (642582)

“…<p>An example of staircase trace reflecting default staircase rules (initial increment = 50 pix, increment step sizes = [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0254195#pone.0254195.ref030" target="_blank">30</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0254195#pone.0254195.ref015" target="_blank">15</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0254195#pone.0254195.ref007" target="_blank">7</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0254195#pone.0254195.ref003" target="_blank">3</a>], 1-up-3-down, 4-reversals, 20 trials). …”

GBE enhanced oxygen consumption of isolated mitochondria and led to an up-regulation of mitochondrial DNA. by Virginie Rhein (243241)

“…<p><b>A</b>) Two-way ANOVA revealed a significant Aβ-induced decrease of the total cellular respiration in isolated mitochondria from APP cells compared to that of control cells (group effect: control vs. …”

The heat map of cytokines/chemokines measurement screening in simian immunodeficiency virus—Zika virus (SIV-ZIKV) co-infected monkeys. by Mehdi R. M. Bidokhti (501484)

Supplementary Material for: Systematic Review and Meta-Analysis of the Impact of Hypoxia on Infarcted Myocardium: Better or Worse? by Pang B. (5404793)

“…Overall, chronic hypoxia was found to have a beneficial effect on the ejection fraction (standard mean difference [SMD] = 5.39; 95% confidence interval [CI], 3.83 to 6.95; <i>P</i> < 0.001) of the infarcted heart, whereas acute hypoxia significantly improved hemodynamics, as indicated by an increase in the maximal rate of rise of left ventricular pressure (SMD = 1.27; 95% CI, 0.27 to 2.28; <i>P</i> = 0.013) and cardiac output (SMD = 1.26; 95% CI, 0.34 to 2.18; <i>P</i> = 0.007) and a decrease in total systematic vascular resistance (SMD = –0.89; 95% CI, –1.24 to –0.53; <i>P</i> < 0.001). …”

Inhibition of thrombin activity by administration of direct thrombin inhibitor Dabigatran etexilate or recombinant murine APC substantially attenuates leukocyte recruitment and pre... by Julian I. Borissoff (280594)

“…<p>(A) Representative hematoxylin and eosin (H&E)-stained sections of atherosclerotic lesions formed in carotid arteries of TM^Pro/Pro:ApoE^−/− mice, which were assigned to different intervention arms (oral Dabigatran etexilate - 7.5 mg DE/gram chow; i.p. administered bolus doses of recombinant murine APC - 2.5 mg/kg/per every 5 days; or placebo) for a total of 6 weeks after cuff placement around the common carotid arteries (top row). …”

Quantitative comparison of protein expression between two <i>P</i>. <i>vivax</i> salivary gland sporozoite field isolates. by Kristian E. Swearingen (2301094)

“…Points in green are proteins with ratios that were not significant at a 5.0% FDR according to the ERFC. …”

Unhinging pathway of FimH under tensile force in MD simulations. by Pavel Aprikian (221712)

“…(b) Sequence of rupture events of contacts between Ld and Pd versus distance from the hinge axis. A contact was defined as broken at the first time point when it ruptured and was not seen to reform within 300 ps. …”

Knockdown of BMPRII did not affect BMP4 elevated basal [Ca²⁺]_i and SOCE in PASMCs. by Yi Zhang (9093)

“…<p>(A) bar graph showing the changes in basal [Ca²⁺]_i in distal PASMCs treated with 50 ng/ml BMP4 (n  =  4 from 120 cells) for 60 h. …”

Eight-year trajectories of changes in health-related quality of life in knee osteoarthritis: Data from the Osteoarthritis Initiative (OAI) by Soili Törmälehto (692961)

“…Group-based trajectory modeling was used to identify patterns of experiencing a decrease of ≥10 points (Minimal Important Change, MIC) in the Quality of Life subscale of the Knee injury and Osteoarthritis Outcome Score compared to baseline. …”

Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

Presentation_1_Biological nitrification inhibitor-trait enhances nitrogen uptake by suppressing nitrifier activity and improves ammonium assimilation in two elite wheat varieties.p... by Adrián Bozal-Leorri (14105895)