COMPARE-MS assay performance by Srinivasan Yegnasubramanian (27577)

“…When 20–100 ng of input DNA are used, COMPARE-MS has a >5000-fold dynamic range, which is ∼500-fold higher than that of methylation-sensitive restriction enzyme used alone and ∼5- to 10-fold higher than that of MBD2-MBD capture used alone. () Plot showing measured output methylated CGIs as determined by COMPARE-MS when decreasing amounts of M.SssI-treated WBC DNA is diluted in 20 ng of untreated WBC genomic DNA. …”

Optimal Filtering Cutoff Frequency Is Determined by the Signal and Noise by Burton W Andrews (274358)

“…Graphically, this is determined by the intersection of the signal and noise PSDs (point A). Increasing the noise variance (red dashed line) decreases the optimal cutoff frequency because the filter must become more restrictive to eliminate the additional noise (point B). …”

The physical, biological, and genetic basis of myopia. by Robert Wojciechowski (399469)

“…Blue dots show SNPs whose p-values for association were between p = 10e-4 and 5e-8 in both datasets. The replication thresholds were the Bonferroni-corrected p-values for a family-wise error rate of 0.05: since the CREAM dataset contained 544 (nonindependent) SNPs that were genomewide significant in 23andMe, the Bonferroni-adjusted p-value threshold for replication was 0.05/544 = 9.2e-05 (or −log₁₀(p) = 4.037). …”

Performance comparison and parameter optimization. by Zeynep Kalender Atak (160796)

“…The plot shows that (i) decreasing the DoC threshold increases the sensitivity of all pipelines as indicated with the blue dotted line; (ii) increasing the VAF threshold increases the specificity with a slight decrease in sensitivity as indicated (in the example of BLAT+VarScan pipeline) with the red dotted line; (iii) the BWA-SW+SSAHA2+Atlas-SNP2 pipeline has the best performance among all pipelines under DoC = 3 & VAF = 0.20 thresholds as indicated with the yellow arrow. …”

Activation of ciliary channels by pregnenolone sulfate. by Steven J. Kleene (233875)

“…For all recordings, cytoplasmic free Ca²⁺ was either 0.1 or 3 μM. Each point shown is the mean of measurements in 3 to 5 cilia (without pregnenolone sulfate) or 7 to 10 cilia (with pregnenolone sulfate). …”

Dynamic time warping network analysis of posttraumatic stress symptoms in Japanese first responders by Florentine H. S. van der Does (21796617)

“…</p> <p><b>Results:</b> The sample consisted of 10211 personnel [97.8% male, mean age 36.7 (<i>SD</i> = 7.5)]. In the undirected DTW analyses, we found that lower network density was associated with a chronic symptom severity trajectory. …”

Supplementary Material for: Comparison of urinary protein/creatinine ratio as an alternative to 24-hour proteinuria in Lupus Nephritis: TUNARI study by Gutiérrez-Peredo G.B. (16439571)

“…Results: We compared 112 samples of 75 patients with LN, with a mean age of 34.5 ± 11.8 years. Of these patients, 85% were women, 87.9% were non-white. …”

Dendritic remodeling of hippocampal CA3 pyramidal neurons. by Suk-Yu Yau (205104)

“…<p>(<b>A</b>) Left: A representative image of a selected neuron for analysis; Right: A neuronal morphology by using Neurolucida software (<b>B</b>) The soma size was not affacted by running and CORT treatment. …”

Histological abnormalities in CNS-<i>Actb</i>KO brains. by Thomas R. Cheever (226943)

“…The region corresponding to this displacement is indicated by dashed lines which also reveals a dramatic decrease in cell body staining in the CA1 neuronal layer. …”

DataSheet1_Effect of Sperm Cryopreservation on miRNA Expression and Early Embryonic Development.docx by Xiaoyu Xu (356293)

“…<p>Although sperm preservation is a common means of personal fertility preservation, its effects on embryonic development potential need further investigation. …”

Table_1_Comparing the Cell Dynamics of Tree-Ring Formation Observed in Microcores and as Predicted by the Vaganov–Shashkin Model.docx by Valentina Buttò (9242369)

“…We obtained microcores over 15 years at 5 sites along a latitudinal gradient in Quebec (Canada). …”

Data_Sheet_1_Epigenetic Effects Promoted by Neonicotinoid Thiacloprid Exposure.pdf by Colin Hartman (11080926)

“…In addition, we found that exposure to thia results in a decrease in H3K9me3 levels in spermatocytes. …”

Investigating the expression of several bone markers in mineralizing 4T1 cells using real-time RT-PCR. by Rachel F. Cox (148193)

“…Positive staining was observed for calcium (red) and calcium phosphate (black/brown) using alizarin red S and von Kossa staining respectively, in the OC group and to a lesser extent in the OC&dex group. (B) There is a decrease in col1a1 (collagen type 1, alpha 1) mRNA expression in the OC&dex group compared to the control group from days 4–28. …”

Analysis of ERE mRNA expression in SIV-infected versus uninfected CD4+ T cells. by Neil C. Sheppard (539902)

“…<p>[<b>A</b>] Flow cytometry analysis staining for SIV Gag p27 and CD4 of uninfected or SIVsmE660-infected CD4+ T cells used for subsequent qPCR analysis [72 h time point is shown]. …”

Effect of disease-related protein modifications on the rate of Ca²⁺ dissociation from the thin filament. by Bin Liu (5899)

“…<p>Panel A shows the time courses of the decrease in IAANS fluorescence as Ca²⁺ was removed by EGTA from thin filament bound control , and the DCM mutants, TnI K36Q , TnT R131W , TnT R141W , TnT R205L and TnT ΔK210 . …”

EUT and DPM testing thresholds as functions of type 1 benefits/harms of prostatectomy ratio. by Athanasios Tsalatsanis (354144)

“…The value of treatment threshold decreases as the ratio benefit/harms of prostatectomy increases (Fig 5a, 5b, 5c and 5d). …”

Table_1_Validation of online mindfulness-enhanced course for stress reduction in teachers.DOCX by Qun Ye (1702021)

“…Background<p>Mindfulness-based interventions have gained popularity as a means of reducing stress and increasing resilience among the preclinical population. …”

Relationship between serum progesterone levels and top-quality blastocyst formation rate. by V. S. Vanni (4030871)

“…<p>With an increase in progesterone levels at induction, a decrease in top-quality blastocyst is observed. …”

Projection resolved optical coherence tomography angiography (PR-OCTA) of migrating intraretinal pigment epithelium (RPE). by Alaa E. Fayed (6703916)

“…There is gradual decrease in the flow signal intensity with increasing PR-OCTA threshold from 0.3 to 0.5 (yellow circles), manifested by a decrease in red pixel percentage from 36.2% to 34.3%. …”

Spraying zinc oxide nanoparticles on pistachios (<i>Pistacia vera</i> L.) for preservation in cold storage by Masoomeh Hasanshahi (18937236)

“…Phenolics and flavonoids of kernels decreased, parallel to a decrease in weight. Nano-ZnO (2%) prevented this reduction well. …”