Phosphorylation of PKA targets is greatest when PKA is colocalized with cAMP production either in the spine or in the dendrite. by Myungsook Kim (2166613)

“…(A2) Bar graph shows mean and s.e.m. of phospho-inhibitor-1 (n = 5 for each condition). …”

IL-1β depletion and IL-1 receptor antagonist treatment alleviated the neutrophilic inflammation. by Wen-Cheng Chao (2817868)

“…<p>The characteristic pulmonary histopathological images (A) of <i>M</i>. <i>marinum</i>-infected <i>Ncf1</i>^<i>-/-</i> mice and WT mice on day-5 with and without IL-1β depletion by a monoclonal antibody directed against IL-1β (150μg on day-1). …”

Adaptation period to diets with low or high fiber on digetibility and faecal characteristics in dogs by T. Ramos (7501706)

“…Fecal consistency of the dogs did not differ among diets and periods (P> 0.05). There was a decrease in fecal pH and ammonia in dogs fed the diet with 15% SH (P< 0.05) after 10 days of feeding (P< 0.05). …”

Artifacts in FRAP arising from the strength of the intentional photobleach. by Tatsuya Morisaki (631489)

“…Artifactual recoveries were observed with the GFP tag (A) but not the TMR-Halo tag (B). Consistent with previous studies <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107730#pone.0107730-Mueller2" target="_blank">[9]</a>, the relative size of the recovery with the GFP-tag increased with decreasing strength of the photobleach (colored curves in A). …”

The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat by Malene Brohus (840080)

“…They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. …”

PA can confer fitness advantage and there is an optimal attachment threshold. by Maor Grinberg (6425468)

“…<p><b>A.</b> Typical simulation dynamics of population size and nutrient concentration over five diel cycles. …”

DataSheet_1_Treatment Interruptions During Stereotactic Body Radiotherapy for Prostate Cancer.docx by Abigail N. Pepin (11966438)

“…Median length of time to complete treatment was 11 days (range 5–155 days). In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. …”

Examination of known somatic cell B-Myb target gene expression patterns following knockdown of B-Myb in ESCs. by Ming Zhan (27937)

“…B) RNA (left) and protein (right) analysis of the B-MYB target gene Polo-like kinase 1 (Plk1) following Bγ-Myb KD with shRNA1 and shRNA5. The effects of B-MYB KD on Plk1 RNA were transient; however, the loss of RNA led to a significant and sustained decrease in its protein abundance. …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Regulation of cardiac transcription factors in liver stem cells co-cultured with cardiomyocytes after minimizing CAMTA1 expression. by Barbara Muller-Borer (159061)

“…The graphs illustrate expression of the transcription factors CAMTA1, CAMTA2, Nk×2.5, Myocardin, cTnT and BetaMHC. A significant decrease in the expression of transcription factors Nkx2.5, Myocardin, cTnT and BetaMHC were measured when CAMTA1 expression was minimized. …”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

Conditional knockout of <i>Ezh2</i> gene in murine hearts caused perinatal lethality. by Li Chen (5749)

“…Semi-quantitative RT-PCR with two different numbers of amplification cycles (30 and 35) was performed on RNA samples purified from WT hearts of E9.5, E10.5, and E11.5. 1 µl or 0.5 µl cDNA from reverse transcription reaction was used for detection of Ezh2 or GAPDH (as a control), respectively. …”

hTTR levels in serum and stomach. by Elena Panayiotou (3925415)

“…<p>hTTR immunoblotting exhibiting a single band at 14KDa (<i>A</i>). hTTR levels measured via immunoblotting in serum of V30M and V30M C1q KO animals of all three age groups indicating higher hTTR in the V30M mice and a gradual decrease in the amount of hTTR present as the animals age (<i>B</i>). hTTR levels measured via immunoblotting in stomach tissue of the V30M and V30M C1q KO animals exhibit a severe decrease in the second age group (<i>C</i>). …”

T-helper cell pathway diagram. by Josephine S. D’Alessandro (814578)

“…Gray lines indicate members of a group. APCs, antigen-presenting cells; CXCR1, chemokine (C-X-C motif) receptor 1; CXCR3, chemokine (C-X-C motif) receptor 3; CXCR5, chemokine (C-X-C motif) receptor 5; CXCL10, chemokine (C-X-C motif) ligand 10; GA, glatiramer acetate; HLADMA, major histocompatibility complex class II, DM alpha; HLADMB, major histocompatibility complex class II, DM beta; HLADQB1, major histocompatibility complex class II, DQ beta 1; ICOSLG, inducible T-cell costimulatory ligand; IL-4, interleukin-4; MHC class II, major histocompatibility complex class II; LTB, lymphotoxin beta (tumor necrosis factor superfamily, member 3); MYD, myeloid differentiation primary response protein; S100A10, S100 calcium-binding protein A10; STAT, signal transducer and activator of transcription; TCR, T-cell receptor; Th, T-helper.…”

Effects of Turbulence Intensity and Biogas Composition on the Localized Forced Ignition of Turbulent Mixing Layers by d’Auzay, C. Turquand

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Dopamine signaling values in control and injured animals. by Eagle Yi-Kung Huang (261488)

“…<p>The mean values of dopamine signal evoked by 1 Pulse/25 Hz, 10V stimulation intensity of the 6-Pa-injured group is plotted in panel A, and by 10 Pulses/25 Hz, 10V stimulation intensity of 6-Pa injury group is plotted in panel B. …”

Nanoviscosity effect on the spin chemistry of an electron donor/Pt-complex /electron acceptor triad - classical and quantum kinetics interpretation by Stefan Riese (5394071)

“…In pTHF, the magnetic field effect on <i>k</i>_± is a single step function decreasing to its limiting value at about 5 times lower fields than in THF. …”

Citalopram does not increase neural signals for reward or effort outcomes. by Jacqueline Scholl (3752851)

“…On the contrary, a more lenient time point—by—time point <i>t</i> test analysis of the time courses revealed that in striatum and vmPFC, citalopram, in fact, decreased the relative reward magnitude outcome signal late in the outcome phase (*<i>p</i> < 0.05 for time point—by—time point two-sided <i>t</i> tests). …”