Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-0 by Mrigank Srivastava (94935)

“…Ned in lysates of alveolar macrophages and lung parenchymal tissue of mock-treated cath K tg mice as compared to mock-treated wild-type mice (A). In addition, cathepsin K protein was determined in lysates of alveolar macrophages (B), freshly isolated type II alveolar epithelial cells (C), lung parenchymal tissue (D), and concentrated BAL fluid supernatant (E) of mock-treated cath K transgenic and wild-type mice by western blot analysis. …”

Perturbing the ORF57-REF/Aly interaction with point mutations decreases cytoplasmic accumulation of viral mRNA. by Richard B. Tunnicliffe (233562)

“…Point mutations of ORF57 residues implicated in direct interaction with REF, and reducing its binding, all caused significant decrease in cytoplasmic accumulation of viral mRNA.…”

Five exemplary spectrograms showing USV emission (rewarded behavior) followed by the release of a food reward. by Agnieszka D. Wardak (17941139)

ChAT knock-down using an antisense oligodeoxynucleotide (AS-ODN) against ChAT, and decreased expression of ChAT in the DRG and spinal cord by Misaki Matsumoto (52354)

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. by Makoto Ohmoto (3065106)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…ACC, acetyl-CoA carboxylase; ATGL, adipose triglyceride lipase; GSEA, gene set enrichment analysis; FASN, fatty acid synthase; HSL, hormone-sensitive lipase; NEFA, nonesterified fatty acid; PL, phospholipid; TAG, triacylglycerol; TOFA, 5-(tetradecyloxy)-2-furoic acid.…”

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

TNFAIP9 expression was increased in mice with chronic kidney disease (CKD) induced by 5/6 nephrectomy (Nx). by Ying Chen (9697)

Subjects:

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-1 by Mrigank Srivastava (94935)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-4 by Mrigank Srivastava (94935)

Conduction slowing at branching points. by Tanmay A. Gokhale (3687244)

“…<p>(a) As the wavefront travels from right to left (direction of arrow) along the principal axis of conduction (obstacle-to-strand ratio: 5), activation isochrones reveal significant slowing at each branching point (top and bottom panels). …”

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

IRE1 depletion decreases heterochromatin, DNA, and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Antibody and antigen responses after treatment with nMAb vs placebo, day 1-90 (pooled nMAb treatments). by Elizabeth S. Munroe (21568166)

(a) Associations Between mAge Acceleration and Visual Attention to the Eyes. by Keiko Ochiai (21453423)

Inhibition of GLS1 decreases the proportion of CCR6 and CXCR3 expressing CD4⁺ T cells. by Zeynep Sener (3146064)

“…BPTES and 968 significantly decrease the proportion of CCR6 expressing cells under normoxia both at day 3 and 5, whereas 968 but not BPTES decrease the proportion of CCR6 expressing cells under hypoxia both at day 3 and 5. …”

PIV analysis of 2-cell stage embryos treated with DMSO or Latrunculin A. by Özge Özgüç (12290245)

SDG decreases iron-induced inflammatory cytokine gene expression in H9c2 cells. by Stephanie Puukila (568109)

SDG decreases iron-induced caspase 3/7 activity in H9c2 cells. by Stephanie Puukila (568109)

Effect of Kif5B RNAi on assisted diffusion during Ad5 transport. by Jie Zhou (28945)

“…Kif5B siRNA leads to a ~20% decrease in Ad5 infectivity. …”