Chronic Drinking During Adolescence Predisposes the Adult Rat for Continued Heavy Drinking: Neurotrophin and Behavioral Adaptation after Long-Term, Continuous Ethanol Exposure by Gina M. Fernandez (2547475)

“…However, only adult onset CET rats displayed decreased hippocampal BDNF levels. Spatial memory, assessed by spontaneous alternation and delayed alternation, was not significantly affected by CET as a function of age of drinking onset, but higher blood–EtOH levels were correlated with lower spontaneous alternation scores. …”

Antioxidant, antiapoptotic and amino acid balance regulating activities of 1,7-dihydroxy-3,4,8-trimethoxyxanthone against dimethylnitrosamine-induced liver fibrosis by Xi-Yuan Zheng (4678468)

“…Our study presented the first elucidated mechanisms of xanthone on liver fibrosis <i>in vivo</i>. This study pointed out that ZYC-1 may be used as a lead compound for hepatofibrosis treatment.…”

The β2AR Pathway Involves PI3K/AKT in Controlling Keratinocyte Migration by Raja K Sivamani (587219)

“…<div><p>(A) (Top) Keratinocytes were treated with procaterol (10 nM, specific β2AR agonist), and the cells were collected at sequential time points and assayed for the expression of phosphorylated AKT (p-AKT) and total AKT. …”

Data_Sheet_1_Combined Transplantation of Olfactory Ensheathing Cells With Rat Neural Stem Cells Enhanced the Therapeutic Effect in the Retina of RCS Rats.PDF by Wei Zhai (1976914)

“…Cytotherapy has become a promising strategy for RDDs. The transplantation of olfactory ensheathing cells (OECs) or neural stem cells (NSCs) has recently been applied for the experimental treatment of RDDs. …”

Data Sheet 2_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

“…Age-period-cohort and Joinpoint regression analyses were conducted to identify temporal trends and critical inflection points across SDI quintiles.</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”

The Effects of Age and the Expression of SPARC on Extracellular Matrix Production by Cardiac Fibroblasts in 3-D Cultures by Jessica Trombetta-eSilva (480640)

“…In contrast, fibroblasts from old mice demonstrated increased efficiency of procollagen processing coupled with decreased production of total collagen. SPARC is a collagen-binding protein previously shown to affect cardiac collagen deposition. …”

Data Sheet 6_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

“…Age-period-cohort and Joinpoint regression analyses were conducted to identify temporal trends and critical inflection points across SDI quintiles.</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”

Table 1_Efficacy of the early start Denver model combined with the TEACCH program in children with autism spectrum disorder.docx by Ling-Ling Ma (7894544)

“…Background<p>Early intervention plays a crucial role in improving outcomes for children with autism spectrum disorder (ASD). …”

Data Sheet 1_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease... by Zhe Sun (328682)

“…Age-period-cohort and Joinpoint regression analyses were conducted to identify temporal trends and critical inflection points across SDI quintiles.</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”

Data_Sheet_1_Periphery Biomarkers for Objective Diagnosis of Cognitive Decline in Type 2 Diabetes Patients.docx by Yanchao Liu (564782)

“…Therefore, discerning who may be more vulnerable to MCI, among the increasing T2DM populations, is important for early intervention and eventually decreasing the prevalence rate of AD. This study was to explore whether the change of plasma β-amyloid (Aβ) could be a biomarker to distinguish MCI (T2DM-MCI) from non-MCI (T2DM-nMCI) in T2DM patients.…”

ZEB2 downregulation induces apoptosis by the activation of Caspase-3 in glioma cells. by Songtao Qi (155648)

“…<p><b>A.</b> Apoptosis in U251 and U87 cells was measured by Annexin V-FITC/propidium iodide (PI) staining following siZEB2 or control treatment. …”

Data_Sheet_2_Distinct Types of Gut Microbiota Dysbiosis in Hospitalized Gastroenterological Patients Are Disease Non-related and Characterized With the Predominance of Either Enter... by Aleksander Mahnic (6107273)

“…Bacterial (V3 V4) and fungal (ITS2) communities were determined in 121 hospitalized gastrointestinal patients from a single ward and compared to 162 healthy controls. …”

Data_Sheet_1_Distinct Types of Gut Microbiota Dysbiosis in Hospitalized Gastroenterological Patients Are Disease Non-related and Characterized With the Predominance of Either Enter... by Aleksander Mahnic (6107273)

“…Bacterial (V3 V4) and fungal (ITS2) communities were determined in 121 hospitalized gastrointestinal patients from a single ward and compared to 162 healthy controls. …”

The locus coeruleus maintains core body temperature and protects against hypothermia during dexmedetomidine induced sedation. by Berta Anuncibay (20108478)

Table_1_Dietary supplementation with mulberry leaf flavonoids and carnosic acid complex enhances the growth performance and antioxidant capacity via regulating the p38 MAPK/Nrf2 pa... by Chunming Liu (72065)

“…Introduction<p>This study aimed to investigate the regulatory effects of mulberry leaf flavonoids and carnosic acid complex (MCC) on the growth performance, intestinal morphology, antioxidant, and p38 MAPK/Nrf2 pathway in broilers.</p>Methods<p>A total of 256 healthy 8-day-old female yellow-feathered broilers were randomly divided into 4 equal groups: a control group (CON) fed a basal diet, an antibiotic group (CTC) supplemented with 50 mg/kg chlortetracycline, and two experimental groups (MCC75, MCC150) fed basal diets with 75 mg/kg and 150 mg/kg of MCC, respectively. …”

Age-related changes in estradiol and longitudinal associations with fat mass in men by Albert Wu (44190)

“…With increasing fat mass, estradiol decreases less than testosterone. From a clinical standpoint these data indicate that obesity is associated with a change in the testosterone to estradiol ratio, but a change in estradiol does not occur unless some other pathology is present.…”

Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities by Meili Tian (5610125)

“…Icariin exerted the anti-tumor effect in a dose-dependent manner by up-regulating p53. During treatment of icariin, p-p53, p21, and Bax levels increased, and Bcl-2 level decreased. …”

Experimental results from the USPIO MRI study. by Hasan Alsaid (345385)

Optimizing Irradiation Dose for <i>Drosophila melanogaster</i> Males to Enhance Heterospecific Sterile Insect Technique Against <i>Drosophila suzukii</i> by Flavia Cerasti (21075827)

Carotid disease and retinal optical coherence tomography angiography parameters in type 2 diabetes: The Fremantle Diabetes Study Phase II by Jocelyn J Drinkwater (9388558)