DataSheet1_Investigation of Chromosomal Structural Abnormalities in Patients With Undiagnosed Neurodevelopmental Disorders.docx by Ye Cao (849948)

“…</p><p>Method: In this study, we applied the mate-pair low pass (∼4X) genome sequencing with large DNA-insert (∼5 kb) in a cohort of 100 patients with neurodevelopmental disorders who did not receive informative results from a routine CNV investigation. …”

Liver growth factor modulated the expression of phospho-Akt and Bcl2 in the striatum and mesencephalon of 6-OHDA-lesioned rats. by Rafael Gonzalo-Gobernado (430684)

“…Results are expressed as percentage of control (naïve striatum and mesencephalon of IP-vehicle treated rats at 13 weeks post-lesion), and represent the mean ± SEM of n individual rats. One way ANOVA were performed in A (p = 0.0064; F_{3, 26} = 5.135, n = 6–11), B (p = 0.014; F_{3, 22} = 4.426, n = 6–7), C (p = 0.0009; F_{3, 22} = 8.003, n = 6–7) and D (p = 0.0047; F_{3, 23} = 5.651, n = 6–7) followed by Newman-Keuls multiple comparison test (*p≤0.05 and **p≤0.01 vs control. …”

<i>Sting</i>^<i>Gt/Gt</i> mice display improve clearance of <i>S</i>. <i>aureus</i> following cutaneous challenge. by Philip O. Scumpia (4246900)

“…(B) Left panel shows Total Flux over 5 minutes, and Right panel shows Mean Radiance (Photons/second). * denotes p<0.05 by one way ANOVA with Tukey’s test for <i>Sting</i>^<i>Gt/Gt</i> mice when compared to WT mice at each time point and represents an n = 8 mice over two separate experiments. ** denotes p<0.05 by one-way ANOVA with Tukey’s test at each time point for <i>Myd88</i>^-/- mice when compared to WT mice at each time point and represents an n = 5 for <i>Myd88</i>^-/- compared to n = 8 WT mice. …”

datasheet1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.docx by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

datasheet1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.docx by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

image1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.tif by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

image1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.tif by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

Significant deregulation of the Jak-Stat signaling pathway. by Carolyn Glass (427882)

“…The x-axis is the significantly downregulated gene and the y-axis denotes reads per million on RNA-Seq analysis. <b>a</b>) In DA-1 <i>Evi1</i> overexpressed cells, <i>Socs1</i> had a 5.7-fold decrease (p = 0.001), <i>Osm</i> had a 13-fold decrease (p = 0.0003), <i>Myc</i> had a 2.5-fold decrease (p = 0.04), <i>Il6</i> had a 2.8-fold decrease (p = 0.02), <i>Csf2rb</i> had a 3.2-fold decrease (p = 0.02). …”

Stimulation of ABCA1 inhibits HCV infection. by Simone Bocchetta (539356)

“…<p>(A) Reduction of intracellular HCV RNA levels in cells that over-express ABCA1. …”

Long-Range Destabilizing Effects of Mutations at the <i>Escherichia coli</i> β Clamp Dimer Interface by Melissa L. Liriano (3967124)

“…The dimeric β clamp is loaded onto primer:template DNA junctions by a five-subunit clamp loader complex. We previously showed that tuning the stability of the β dimer interface affected clamp opening dynamics and function. …”

Single Molecule Detection of Nitric Oxide Enabled by d(AT)₁₅ DNA Adsorbed to Near Infrared Fluorescent Single-Walled Carbon Nanotubes by Jingqing Zhang (84882)

“…We report the selective detection of single nitric oxide (NO) molecules using a specific DNA sequence of d(AT)₁₅ oligonucleotides, adsorbed to an array of near-infrared fluorescent semiconducting single-walled carbon nanotubes (AT₁₅−SWNT). …”

Tyramine-mediated reduction in GABA synaptic release requires SER-2. by Jamie L. Donnelly (397302)

“…Arrow depicts tyramine application time point. Each point represents the IPSC frequency calculated over a 5-s time window as indicated. …”

Table1_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.DOCX by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

Table7_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.DOCX by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

Table4_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.XLSX by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

DataSheet1_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.PDF by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

Table2_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.XLSX by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

Table6_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.XLSX by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

Table8_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.DOCX by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”

Presentation1_Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma.pdf by Pavan Vedula (11984267)

“…Our results suggest a global change in protein processing and regulation that occurs in response to SARS-CoV-2, and the existence of a posttranslational COVID-19 signature that includes an elevation in threonine phosphorylation, a change in glycosylation, and a decrease in arginylation, an emerging posttranslational modification not previously implicated in infectious disease. …”