Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity by Konstantin V. Salojin (567844)

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy by Eleni N. Tsakiri (6614297)

Elevated <i>Mirc1/Mir17-92</i> cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages by Mia F. Tazi (559529)

Data_Sheet_1_Outcomes of patients with acute respiratory failure on veno-venous extracorporeal membrane oxygenation requiring additional circulatory support by veno-venoarterial ex... by Rolf Erlebach (12614975)

“…Median (Interquartile Range) age was 49 (28–57) years and SOFA score was 14 (12–17) at V-VA ECMO upgrade. Vasoactive-inotropic score decreased from 53 (12–123) at V-VA ECMO upgrade to 9 (3–37) after 24 h of V-VA ECMO support. …”

Actomyosin network R_g,f / R_g,i and S for various <i>χ</i>. by Konstantin Popov (2617535)

“…Global alignment peaks around <i>χ</i> = 0.5 to 2, and decreases for values outside of this range. …”

Recovery from inactivation kinetics of I_to (i.e. the fastest inactivation component of the outward K⁺ currents) in WT and Kv4.2-/-cardiomyocyte. by Jie Liu (15128)

“…The early portions of traces following the depolarizing test-pulse are re-shown on a faster (expanded to 300 ms/bar scale) time scale in the inset (broken box) to better illustrate the properties of the time-course (of the recovery) of the peaks of the I_to K^<b>+</b> currents as a result of membrane repolarization (to -80mV). …”

Multifunctional self-healing polymeric nanocomposite coatings for corrosion inhibition of steel by Ubaid F.

Get full text
Get full text

Motion sensor-based haptic master controller with finger band soft actuator for surgical robots by Yuta Soga (18434028)

“…The haptic force presentation can be realized by the pneumatic pressure of FBSA, which can be highly integrated into the controller mechanism to maintain precise manipulability. The FBSA can present a pressing force of 3.7 N for a small-sized finger and 5.1 N for a large-sized finger at an internal pressure of 60 kPa, and there is a monotonically increasing and decreasing relationship between the air pressure and the pressing force. …”

SKN-1 directly regulates target genes during the UPR. by Kira M. Glover-Cutter (218155)

“…<p>(A–L) ER stress-induced SKN-1 recruitment and transcriptional activation was analyzed at the SKN-1-regulated genes <i>pcp-2</i> (A–D), <i>atf-5</i> (E–H), and <i>gst-4</i> (I–L). …”

THS exposure results in inflammation and excess production of pro-inflammatory cytokines/chemokines in lung tissue. by Manuela Martins-Green (516426)

“…(<b>B,C</b>) A multiplex cytokine array shows that many pro-inflammatory cytokines are elevated in THS-exposed animals (red) compared to control (blue) whereas some anti-inflammatory cytokines are decreased. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Cell proliferation controls the duration of tract formation. by Richard Bailleul (7456496)

“…(D) Simulations of the unified model with initial conditions corresponding to the Japanese quail show that dot rows form through longer simulation times <i>Ts</i> (in white) when the overall proliferation rate <i>α</i>_<i>n</i> decreases. (E) The dynamic appearance of tracts occurs in a progressively slower manner in cultured explants of Japanese quail skins (prepared prior to the differentiation of the feather field) observed from 1 to 6 days (T + 1 to T + 6) after exposure to increasing pulses of colchicine treatment (from 30 minutes to 3 hours), compared to untreated explants (schematics represent fr in the resulting tract with the colour code used previously in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000448#pbio.3000448.g002" target="_blank">Fig 2</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000448#pbio.3000448.g005" target="_blank">Fig 5</a>). …”

Figure S1 - Effectiveness of the Histone Deacetylase Inhibitor (S)-2 against LNCaP and PC3 Human Prostate Cancer Cells by Anna Laurenzana (296271)

“…In all cases, tumor volumes in untreated mice were significantly larger relative to those of drug-treated mice to suggest that (S)-2 was capable of reaching the cancer cells and decreasing their growth rates. Photographs are representative of a tumor mass from a mouse treated with either the vehicle or (S)-2, respectively. …”

Derl2 is required for CDT intoxication. by Aria Eshraghi (607023)

“…Cells were then fixed and stained with DAPI (nuclei, blue), Concanavalin A (ER, red) and α-Hd-CdtB (green) antibody. White scale bars indicate 5 µm. …”

DataSheet_2_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.pdf by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

DataSheet_6_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.zip by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

Image_2_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.jpeg by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

Image_3_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.jpeg by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

DataSheet_4_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.zip by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

DataSheet_1_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.pdf by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”