6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

EGCG decreases RSK2-mediated cell viability. by Hanyong Chen (320863)

“…Differences were evaluated using the Student’s t-test and the asterisk (*) indicates a significant decrease in viability in RSK2^+/+ MEFs compared to RSK2^-/- MEFs (<i>p</i> < 0.05).…”

Knockdown of VGLUT1 results in a concomitant decrease in synaptic expression of synapsin and synaptophysin. by Corbett T. Berry (296520)

“…(<b>E</b>) Synaptophysin was not decreased in KD neurons co-expressing VGLUT1 (<i>V1</i>, VGLUT1 expressing neurons; p = 0.940; n = 244 and 96 puncta from 13 and 9 axons for SCR and V1, respectively, from a representative experiment. …”

Decreased Klotho expression in kidneys from hyperlipidemic mice. by Cristina Sastre (503532)

Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…One hundred percent cell viability corresponds to the number of living cells incubated with transfecting agent only. Results are the mean ± SD of two independent experiments containing 8 replicates for each condition. * = <i>p</i><0.05, ** = <i>p</i><0.01, *** = <i>p</i><0.001, significant decrease compared to untreated cells (TA) or to siRNA Control (Kruskal & Wallis followed by Tukey and Dunnet test).…”

Promoter activities of DNA-DRR genes decreased with DEC. by Hideaki Nakamura (402108)

Silencing of TET3 acted to decrease mitochondrial respiration in N2A cells. by Valeria Leon Kropf (17797623)

Is the only transcript decreasing in cells following tunicamycin treatment by Maho Niwa (7152)

Bone mass and formation are decreased in Akt1-/- mice. by Naohiro Kawamura (33999)

Decreased β-cell mass in Hq mutant mice. by Fabienne T. Schulthess (13268705)

Decreased fibrin deposition in hypoxic C3−/− mice. by Eileen M. Bauer (337320)

Retinoschisin secretion into the conditioned medium is decreased by addition of taxol. by Eiko Kitamura (349087)

“…Retinoschisin secretion into the medium decreases in a dose-dependent manner between 0.5 µM and 10 µM taxol. …”

CHIP overexpression decreases α-syn oligomer levels. by Lorraine V. Kalia (355943)

Silencing of dynamin II decreases apoE secretion. by Maaike Kockx (154125)

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …”

Increased proliferation and decreased luminal apoptosis in IGFIR structures by Gina M Yanochko (20949)

Autophagy inhibition decrease LAMP2 levels and survival of neuroendocrine differentiated LNCaP cells. by Cecilia Morell (729630)

MPCs in aged myofibers display decreased myogenic activity. by Grégory Lacraz (370661)

Decreased NTAL expression after shRNA silencing. by Iva Polakovicova (621362)

Bortezomib decreases osteoclasts and improves fracture repair in mice. by Hengwei Zhang (2397610)