Morphological, functional and epistatic effects of <i>ninl</i> and <i>dzank1</i> knockdown in zebrafish retina. by Margo Dona (816015)

“…(h) Quantification of Outer Segment length, shown as a scatter graph where each datapoint represents the mean OS length in one larva, revealed a significantly decreased length of outer segments in <i>ninl</i> (2ng/nl), <i>dzank1</i> (6ng/nl) and <i>ninl/dzank1</i> double morphants as compared to controls. …”

Table_1_Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and N... by Yee Qian Lee (10727655)

“…Increased caspase-3 activity and decreased bcl-2 concentration upon treatment indicate that MS13 induces apoptosis in these cells in a dose- and time-dependent manner. …”

Transgenic pmes-<i>Bmp4</i> reactivates Smad1/5/8 signaling in the dermal mesenchyme in <i>Gpr177^K14</i>/Tg-pmes-<i>Bmp4</i>. by Xiao-Jing Zhu (645748)

“…P-Smad1/5/8 activity (white arrowheads) is preferentially decreased in dermis of limb skin in <i>Gpr177^K14</i> mice and increased in dermis of <i>Gpr177^K14</i>/Tg-pmes-<i>Bmp4</i> mice (green arrowheads) (A–C). …”

Genetic perturbation analysis of the stoichiometry control system. by Koji Ishikawa (703501)

“…The untagged dosage-compensated protein was expressed from multicopy plasmid pTOW40836 containing the native regulatory sequences, including promoter and 5´ and 3´ untranslated regions. If the target gene is subjected to dosage compensation, the level of the TAP-tagged target protein expressed only from the chromosome decreases upon an increase in gene copy number (Multi) compared to vector control (Single). …”

Discovery of Potent, Selective, and Brain-Penetrant 1<i>H</i>‑Pyrazol-5-yl‑1<i>H</i>‑pyrrolo[2,3‑<i>b</i>]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors by Makoto Fushimi (1714441)

“…Scaffold hopping and lead optimization of <i>N</i>-(2,4-difluorobenzyl)-3-(1<i>H</i>-pyrazol-5-yl)­imidazo­[1,2-<i>b</i>]­pyridazin-6-amine <b>1</b> guided by a cocrystal structure of compound <b>1</b> bound to ALK resulted in the identification of (6-(1-(5-fluoropyridin-2-yl)­ethoxy)-1-(5-methyl-1<i>H</i>-pyrazol-3-yl)-1<i>H</i>-pyrrolo­[2,3-<i>b</i>]­pyridin-3-yl)­((2<i>S</i>)-2-methylmorpholin-4-yl)­methanone <b>13</b> as a highly potent, selective, and brain-penetrable compound. …”

Bayesian skyride plot (BSP) for the three genomic segments of RVFV. by P. O. Ly Soumaré (169424)

Structural maturation of the FC in high pressure frozen cells. by Johanna L. Höög (402710)

Concentration-response curves to acetylcholine (ACh) before/after inhibition of EET formation by PPOH (10 μmol/l) or 17-ODYA (10 μmol/l) in phenylephrine (PE)-preconstricted renal... by Dandan Yin (4373071)

The effect of IL-17A on IκBζ - RGS4 signaling. by Hirotada Akiho (559455)

“…(<b>F</b>) The effect of IL-17A, IL-1β, or IL-4 on RGS 4 activity was assessed with or without SN50, a p65 translocation inhibitor, or IκBζ siRNA (n = 4∼5). …”

Image 5_Investigation of Tongqiao Huashuan Granules’ effect on hippocampal neuron autophagy in vascular dementia rats via the PI3K/Akt-mTOR signaling pathway using network pharmaco... by Xiaoqu Jiang (20912471)

Summary of treatment groups and regimens. by Denise Evans (288201)

“…</p><p>In assessing provider costs, a total of 112 medical records were reviewed (37.5%, 41.1% and 21.4% on BPaL, the SSOR and SLOR respectively). …”

Assessment of kidney function in the elderly: a population-based study by Marina Constante Dutra (12729314)

“…With regard to the glomerular filtration rate, 26.2% had a normal rate; 60.2% showed a slight decrease; 13.0% a moderate decrease; 0.5% severe kidney function decline; and 0.1% extreme fall. …”

Outcomes of protocolised analgesia and sedation in a neurocritical care unit by Leana Mahmoud (5314205)

“…There was a decrease in fentanyl (cost ratio = 0.8, CLs 0.5, 1.1) and propofol costs (cost ratio = 0.6, CLs 0.5, 0.8). …”

Galactose-1-phosphate uridyltransferase (GalT), an <i>in vivo</i>-induced antigen of <i>Actinobacillus pleuropneumoniae</i> serovar 5b strain L20, provided immunoprotection against... by Fei Zhang (85787)

“…Indirect enzyme-linked immunosorbent assay (ELISA) confirmed that GALT specific antibodies could not be induced by inactivated APP L20 or MS71 whole cell bacterin preparations. A recombinant fusion GALT protein derived from APP L20, however has proven to be an effective cross-protective antigen against APP sevorar 1 MS71 (50%, 4/8) and APP sevorar 5b L20 (75%, 6/8). …”

Changes in trust in law enforcement after Jacob Blake’s shooting among Black respondents. by Jonathan Ben-Menachem (19648290)

Changes in trust in law enforcement after Jacob Blake’s shooting among White respondents. by Jonathan Ben-Menachem (19648290)

RhoA signaling contributed to the JNK-regulated cell differentiation and migratory polarity formation. by Jiao Luo (156722)

“…(B) After 5 days with SP600125 treatment, ALPase staining showed that RhoA Q63L could partly rescue SP600125-regulated inhibition of mDPCs differentiation. …”

Stability of Afsup. by Gabriele Sass (335744)

“…B: 10AFsup was stored at 4°C for up to 12 months, and tested for protective activity against 5 μM pyoverdine (PYOV) every 3 months. A portion of the 10AFsup was stored at room temperature (RT), and tested after 12 months of storage. …”

Supplementary Material for: Postprandial Symptoms in a Mixed-Meal-Test after Bariatric Surgery – Clinical Experience and a Critical Review of Dumping Syndrome Definition and Manage... by Samigullin A. (19835253)

“…A blood glucose decrease below 70 mg/dl was not associated with symptoms. …”

Image_5_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)