Image_1_Rapamycin Protects Against Peritendinous Fibrosis Through Activation of Autophagy.jpg by Wei Zheng (25452)

“…In a rat model of tendon injury, we observed dysregulated autophagy during excessive extracellular matrix deposition. …”

Long noncoding RNA <i>CA7-4</i> promotes autophagy and apoptosis via sponging <i>MIR877-3P</i> and <i>MIR5680</i> in high glucose-induced vascular endothelial cells by Xuan Zhao (356028)

“…Although the role of long noncoding RNA in regulating cell fate has received widespread attention, long noncoding RNAs (lncRNAs) that can both regulate autophagy and apoptosis need to be discovered. In this study, we identified that a small chemical molecule, 3-benzyl-5-([2-nitrophenoxy] methyl)-dihydrofuran-2(3H)-one (3BDO), synthesized by us, could inhibit VEC autophagy and apoptosis induced by a high concentration of glucose. …”

Pcl3 promotes ESC self-renewal. by Julie Hunkapiller (177548)

“…Graph represents average expression from 3–6 different clones. (B) A portion of cells transduced with <i>Pcl3</i> shRNA, but not scramble shRNA, are larger, flatter, and less dense, signifying a decrease in ESC cell morphology. …”

Interplay between Active Chromatin Marks and RNA-Directed DNA Methylation in <i>Arabidopsis thaliana</i> by Maxim V. C. Greenberg (128096)

S-nitrosoglutathione inhibits pyroptosis of kidney tubular epithelial cells in sepsis via the SIRT3/SOD2/mtROS signaling pathway by Heng Fan (814041)

Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos by Yun Long (1421299)

Alterations of Marginal Zone (MZ) B cells during <i>T. brucei</i> infections. by Magdalena Radwanska (73816)

“…The decrease in total number of MZ B-cells per spleen was calculated for different time points during infection (B), based on the total amount of cells harvested per spleen at each time point (C). …”

QTL mapping of male sterility and transmission pattern in progeny of Satsuma mandarin by Shingo Goto (739660)

“…The QTL for APF (<i>MS-F1</i>) was detected on linkage group 6 with a significant LOD score (5.71) and 63.6% of variance explained. …”

Table_1_Impacts of glacial and sea-ice meltwater, primary production, and ocean CO2 uptake on ocean acidification state of waters by the 79 North Glacier and northeast Greenland sh... by Agneta Fransson (471604)

“…This was most pronounced near the 79NG front in 2012, where surface stratification was most pronounced coinciding with large glacial meltwater fractions. Freshening decreased Ω_Ar by 0.4 at the 79NG front was compensated by biological CO₂ drawdown by ~0.5. …”

Regulation of GGA expression alters APP processing and sAPP secretion. by Bjoern von Einem (751380)

“…Equal expression of all proteins was controlled by Western blot analysis. We found, similar to the results in HEK293 (data not shown), significantly decreased levels of sAPPα and sAPPβ in conditioned media upon GGA overexpression compared with control, as measured by ELISA. …”

Table_1_The Influence of Social Isolation on Social Orientation, Sociability, Social Novelty Preference, and Hippocampal Parvalbumin-Expressing Interneurons in Peripubertal Rats –... by Milica Potrebić (12494344)

“…The main findings are the following: (1) in GH rats, the preference for social space is not evident regardless of animals’ age, while sociability becomes apparent in mid-adolescence strictly through consummatory behavior, along with complete SNP (appetitive, consummatory); (2) SH promotes staying in a social chamber/space regardless of animals’ age and produces an appetitive preference for it only in early-adolescent animals; (3) SH promotes sociability (appetitive, consummatory) regardless of the animals’ age and prevents the SNP; (4) the preference for a social odor is displayed in all the groups through consummatory behavior, while appetitive behavior is evident only in SH rats; (5) the response to social odors does not commensurate directly to the response to conspecifics; (6) SH does not influence PVI in the hippocampus, except in the case of early-adolescence when a transient decrease in the dentate gyrus is observed. …”

Image_1_Impacts of glacial and sea-ice meltwater, primary production, and ocean CO2 uptake on ocean acidification state of waters by the 79 North Glacier and northeast Greenland sh... by Agneta Fransson (471604)

“…This was most pronounced near the 79NG front in 2012, where surface stratification was most pronounced coinciding with large glacial meltwater fractions. Freshening decreased Ω_Ar by 0.4 at the 79NG front was compensated by biological CO₂ drawdown by ~0.5. …”

Transparent Sodium Lignosulfonate/Phosphorylated Sodium Alginate/Cellulose Composite Films with Flame-Retardant and UV to Blue Light-Shielding Performance by Jingyuan Zhang (6535169)

Image_3_Real clinical experience after one year of treatment with tolvaptan in patients with autosomal dominant polycystic kidney disease.JPEG by Javier Naranjo (13879235)

“…The main causes of treatment withdrawal were the aquaretic effects (11%), eGFR deterioration (5%), and hepatic toxicity (2.3%). eGFR decreased significantly after 1 month of treatment without further changes. …”

Image_6_Real clinical experience after one year of treatment with tolvaptan in patients with autosomal dominant polycystic kidney disease.JPEG by Javier Naranjo (13879235)

“…The main causes of treatment withdrawal were the aquaretic effects (11%), eGFR deterioration (5%), and hepatic toxicity (2.3%). eGFR decreased significantly after 1 month of treatment without further changes. …”

Supplementary Material for: Urine Osmolality and Renal Outcome in Patients with Chronic Kidney Disease: Results from the KNOW-CKD by Lee M.J. (4145941)

“…However, results about the association between urine osmolality and adverse renal outcomes in chronic kidney disease (CKD) are conflicting. We investigated the association between urine osmolality and adverse renal outcomes in a nationwide prospective CKD cohort. …”

datasheet1_L-Citrulline Supplementation Increases Plasma Nitric Oxide Levels and Reduces Arginase Activity in Patients With Type 2 Diabetes.docx by Alia Shatanawi (711956)

“…HG (25 mM, 72 h) caused a 2-fold increase in arginase activity in BAECs and decreased NO production by 30%. …”

Transparent Sodium Lignosulfonate/Phosphorylated Sodium Alginate/Cellulose Composite Films with Flame-Retardant and UV to Blue Light-Shielding Performance by Jingyuan Zhang (6535169)

Table_1_Real clinical experience after one year of treatment with tolvaptan in patients with autosomal dominant polycystic kidney disease.DOCX by Javier Naranjo (13879235)

“…The main causes of treatment withdrawal were the aquaretic effects (11%), eGFR deterioration (5%), and hepatic toxicity (2.3%). eGFR decreased significantly after 1 month of treatment without further changes. …”

Tracing mantle sources in the northern Lau back-arc basin by independent component analysis of basalt isotopic compositions by Xichang Wu (6170957)

“…We identified three ICs in the five-dimensional space of Sr-Nd-Pb isotopic ratios, which can account for 96.5% of the isotopic variance. …”