The direction of correlations for age associated methylation alterations differ dependent upon CpG island status. by Brock C. Christensen (109103)

“…Age-associated methylation is significantly decreased among classes with a high prevalence of non-CpG-island loci (<i>P</i> = 5.2E-08).…”

Results from the first culturally tailored, multidisciplinary diabetes education in Lebanese adults with type 2 diabetes: effects on self-care and metabolic outcomes by Sukkarieh-Haraty, Ola

“…This pilot-study tested the effect of culturally-tailored education targeting diabetes selfcare on glycemia and cardiovascular risk factors of Lebanese with type 2 diabetes mellitus (T2DM) (n = 27; Age: 61 ± 10 yrs, 59% males, HbA1c: 8.98 ± 1.38%). Results: Diabetes self-care (Diet, Self-Monitoring Blood Glucose and foot care) improved after 6 months, which was reflected in a significant drop in glycemic levels (HbA1c:-0.5%; FPG: − 38 mg/dl), and cholesterol/HDL ratio (4.45 ± 1.39 vs. 4.06 ± 1.29). …”
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Supplementary Tables from ER⁺ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors by Angel L. Guerrero-Zotano (7063892)

“…A decreased gene expression translates into a geometric mean change < 1 . …”

Developmental changes in percentage of EEG total power within the delta and theta frequency ranges during vigilance states of the neonatal mouse. by Nicholas Rensing (3686332)

“…<p>(<b>A</b>) During wakefulness, percentage of delta (1-4Hz) in EEG decreases until P17 and percent theta (4–8.5Hz) increases starting at P14. p<0.001, compared to ***P21; ### P17; ◆◆◆ P14; p<0.01 compared to ## P17; p<0.05 compared to ^{<b><i>&</i></b>}P12 by one-way repeated measures ANOVA with Tukey; n = 8–9 mice per group. …”

Negative regulation of <i>sNPF/NPY</i> by insulin signaling. by Seung-Hyun Hong (136797)

“…<p>(A, B) Insulin treatment increased FoxO1 phosphorylation and decreased <i>NPY</i> expression in mouse hypothalamic GT1-7 cells while insulin with AKT inhibitor co-treatment slightly decreased FoxO1 phosphorylation and increased <i>NPY</i> expression. …”

DataSheet_1_2-Deoxy-D-glucose Alleviates Collagen-Induced Arthritis of Rats and Is Accompanied by Metabolic Regulation of the Spleen and Liver.zip by Hongxing Wang (3165948)

“…The changes in the gene-metabolite network of bile secretion in the spleen correlated with a decreased plasma L-acetylcarnitine level in CIA rats and an increase following 2-DG treatment. …”

RER1 expression significantly reduces αSyn levels. by Hyo-Jin Park (4233949)

“…(B) Wild type RER1 expression significantly decreased αSyn levels (mean, 87.8 ±7.1%), but expression of RER1Δ25 resulted in significantly smaller effects on levels of αSyn (mean, 24.3 ±10.6%) (*p<0.05, **p<0.01; F_2,6 = 17.31, p = 0.0032) (n = 5/control, n = 7/RER1, n = 3/ RER1Δ25) in HEK293. …”

Molecules altering the synchrony index, modify Cx36 expression and the size of Cx36 plaques. by Sabine Bavamian (148288)

“…The bars show means + SE ratio of the Cx36 to the <i>β</i>-actin signal, as evaluated by densitometric analysis of 5 independent experiments. *p<0.05 versus DMSO-exposed controls; (<i>B</i>) The volume density (Vv) of Cx36 was increased by some of the drugs that enhanced MIN6 cell synchronization, and decreased by all the drugs decreasing this synchronization. …”

RT-qPCR quantification of the expression of <i>Lin28B</i> in peripheral blood monoculear cells. by Shu-Wen Cheng (484650)

“…<p><i>Lin28B</i> was expressed in 3 cases (5%) in the non-HCC controls (1 in healthy group and 2 in hepatitis group) and in 32 cases (33.3%) in the HCC group. …”

Reduced synaptic density in human postmortem pneumococcal meningitis neocortical brain tissue samples. by Carolin Wippel (421278)

“…<p><i>A.</i> Schematic representation of the analyzed neocortical regions. …”

Effect of baicalein on the mobility and invasive potency of human gallbladder carcinoma GBC-SD and SGC996 cells. by Tian-Yu Liu (686078)

“…<p>Cells were treated with 7.5, 15, 30 and 60μmol/L baicalein for 12 h prior to the migration (A) or invasion (B) assay.…”

Climatological ranges and average annual anomalies for U.S. Pacific coral reef ecosystems. by Jamison M. Gove (404321)

“…Islands and atoll names are presented as a three-letter code (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061974#pone-0061974-t001" target="_blank">Table 1</a> for full location names), grouped and color-coded by region (see Fig. 1 for map of locations), and oriented by decreasing latitude from left to right (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061974#pone-0061974-t001" target="_blank">Table 1</a> for specific positions). …”

Data_Sheet_1_On-farm antimicrobial usage in commercial turkey production in the United States, 2013–2021.PDF by Randall S. Singer (8097428)

“…The estimated percentage of turkey poults placed that received hatchery antimicrobials decreased from 96.9% in 2013 to 40.5% in 2021. The use of in-feed antimicrobials was practically eliminated, with in-feed tetracycline being the only medically important antimicrobial used in 2021. …”

Table_1_On-farm antimicrobial usage in commercial turkey production in the United States, 2013–2021.XLSX by Randall S. Singer (8097428)

“…The estimated percentage of turkey poults placed that received hatchery antimicrobials decreased from 96.9% in 2013 to 40.5% in 2021. The use of in-feed antimicrobials was practically eliminated, with in-feed tetracycline being the only medically important antimicrobial used in 2021. …”

Supplementary Material for: Impact of 14 days of bed rest in older adults and an exercise countermeasure on body composition, muscle strength and cardiovascular function: Canadian... by Hajj-Boutros G. (16989918)

“…Body weight significantly decreased in both groups. Total and leg lean masses decreased in both groups. …”

Supplementary Material for: Impact of 14 days of bed rest in older adults and an exercise countermeasure on body composition, muscle strength and cardiovascular function: Canadian... by Hajj-Boutros G. (16989918)

“…Body weight significantly decreased in both groups. Total and leg lean masses decreased in both groups. …”

In-depth hepatoprotective mechanistic study of <i>Phyllanthus niruri</i>: <i>In vitro</i> and <i>in vivo</i> studies and its chemical characterization by Marwa I. Ezzat (8308170)

“…Compounds <b>C1</b>, <b>C2</b>, <b>C5</b>, and <b>C7</b> showed the highest (<i>p</i>< 0.001) hepatoprotective potency, while <b>C3</b>, <b>C4</b>, and <b>C6</b> exhibited a moderate (<i>p</i>< 0.001) activity. …”

Behavioral characterization of <i>Del-Dup</i> cohorts. by Thomas Arbogast (1783087)

“…The 8-min cue session was performed 5 h after the context session. A sequence of 2-min without cue and 2 min with light/auditory conditioning stimulus was repeated twice. …”

Adsorption of Congo Red Dye Using Activated Carbon-Fe3O4 Composite by Mahmud, Nafis

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Extracellular VEGF levels in vivo. by Ulrika W. Nilsson Åberg (343075)

“…<p>Microdialysis in normal breast tissue and abdominal subcutaneous fat was performed in five sets of women; in follicular and luteal phases of six premenopausal women, in two consecutive luteal phases of five premenopausal women, in nine premenopausal women before and after the addition of 25 g of ground flaxseed/day to their diet, in five healthy postmenopausal women, and in 11 women before and after tamoxifen therapy as an adjuvant for early breast cancer (on two women microdialysis was performed in breast tissue only). …”