Image2_The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes.JPEG by Mohamed Ahmed (376976)

“…We examined eNAMPT (extracellular nicotinamide phosphoribosyltransferase), a critical inflammatory DAMP and TLR4 ligand, as a potential therapeutic target to reduce IAI severity and improve adverse fetal/neonatal outcomes.…”

High Fat Diet-Induced Changes in Mouse Muscle Mitochondrial Phospholipids Do Not Impair Mitochondrial Respiration Despite Insulin Resistance by Joris Hoeks (194696)

“…Interestingly, 20 weeks of HFD descreased mono-unsaturated FA while n-6 poly-unsaturated FA (18∶2n6, 20∶4n6, 22∶5n6) showed a pronounced increase (+4.0%, p<0.001). …”

Image_2_Vitamin C Deficiency in Patients With Acute Myeloid Leukemia.jpeg by Tiziana Ottone (10101109)

“…Conversely, vitamin C concentration was significantly lower in AML as compared to HDs (p<0.0001), inversely correlated with peripheral blast‐counts (p=0.029), significantly increased at the time of complete remission (CR) (p=0.04) and further decreased in resistant disease (p=0.002). Expression of the main vitamin C transporters SLC23A2, SLC2A1 and SLC2A3 was also significantly reduced in AML compared to HDs. …”

Data_Sheet_1_The Association Between Risk Perception and COVID-19 Vaccine Hesitancy for Children Among Reproductive Women in China: An Online Survey.docx by Min Du (292028)

“…Vaccine hesitancy was associated with lower perceived susceptibility (moderate: aOR = 1.72, 95%CI: 1.17–2.54, P = 0.0061; low: aOR = 2.44, 95%CI: 1.60–3.70, P < 0.0001), high perceived barriers (aOR = 2.86, 95%CI: 1.57–5.22, P < 0.0001), and lower perceived benefit (moderate: aOR = 3.29, 95%CI: 2.30–4.70, P < 0.0001; low: aOR = 4.59, 95%CI: 2.98–7.07, P < 0.0001), but not with perceived severity.…”

Image1_The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes.JPEG by Mohamed Ahmed (376976)

“…We examined eNAMPT (extracellular nicotinamide phosphoribosyltransferase), a critical inflammatory DAMP and TLR4 ligand, as a potential therapeutic target to reduce IAI severity and improve adverse fetal/neonatal outcomes.…”

Image_1_Vitamin C Deficiency in Patients With Acute Myeloid Leukemia.jpeg by Tiziana Ottone (10101109)

“…Conversely, vitamin C concentration was significantly lower in AML as compared to HDs (p<0.0001), inversely correlated with peripheral blast‐counts (p=0.029), significantly increased at the time of complete remission (CR) (p=0.04) and further decreased in resistant disease (p=0.002). Expression of the main vitamin C transporters SLC23A2, SLC2A1 and SLC2A3 was also significantly reduced in AML compared to HDs. …”

Image_3_Vitamin C Deficiency in Patients With Acute Myeloid Leukemia.jpeg by Tiziana Ottone (10101109)

“…Conversely, vitamin C concentration was significantly lower in AML as compared to HDs (p<0.0001), inversely correlated with peripheral blast‐counts (p=0.029), significantly increased at the time of complete remission (CR) (p=0.04) and further decreased in resistant disease (p=0.002). Expression of the main vitamin C transporters SLC23A2, SLC2A1 and SLC2A3 was also significantly reduced in AML compared to HDs. …”

Genome-wide, evolutionary, and functional analyses of ascorbate peroxidase (APX) family in Poaceae species by Douglas Jardim-Messeder (14242955)

“…Among rice plants silenced to different isoforms, plants silenced to cAPX showed a higher decrease in total APX activity and an increase in hydrogen peroxide levels. …”

The effect of increase in blood glucose level on hearing loss by Guven Akcay (14434750)

“…A significant decrease was also found in distortion product otoacoustic emission amplitudes at 4, 6, 8, and 10 kHz in the high blood glucose and diabetes mellitus groups compared to the control group. …”

Effects of acute Theiler’s murine encephalomyelitis virus (TMEV)-infection (<i>experiment I</i>) upon cytokine expression and phenotypical changes in spleens of interleukin-10 rece... by Ann-Kathrin Uhde (3110976)

“…(J) Flow cytometry revealed a relative increase of CD19⁺ B cells and a simultaneous decrease of CD4⁺ T cells (K) in the spleen of infected mice following IL-10R blockade at 14 dpi. …”

Table_1_Intermittent Hypoxia Exposure Helps to Restore the Reduced Hemoglobin Concentration During Intense Exercise Training in Trained Swimmers.xlsx by Xiquan Weng (8795453)

“…<p>In prolonged intense exercise training, the training load of athletes may be reduced once their hemoglobin concentrations ([Hb]s) are decreased dramatically. We previously reported that intermittent hypoxia exposure (IHE) could be used to alleviate the decrease of [Hb] and help to maintain the training load in rats. …”

Impact of exercise initiation at 24-months-old on aging-related motor decline. by Jennifer C. Arnold (4621795)

“…Aging produced a significant decrease in movement number (F_(5,60) = 29.49, <i>p<</i>0.0001). …”

Plasma pharmacokinetics and brain uptake of 2B3-101 and pegylated liposomal doxorubicin in healthy mice. by Pieter J. Gaillard (506968)

“…<p>(A) Plasma concentration after 1 IV dose (5 mg/kg in 3 mice per group per time point) decreases with time for both liposomal formulations. …”

Comparative proteomic analysis of the moderately resistant and susceptible peanut cultivars during infestation by <i>Cylindrocladium parasiticum</i> by Xinyu Chen (47670)

Image_1_Alterations of the Gut Microbiome Composition and Lipid Metabolic Profile in Radiation Enteritis.jpg by Yiyi Li (1968925)

“…During RE activity, the intestinal inflammation of the mice was confirmed by typical signs, symptoms, imaging findings and pathological evidences. 16S datasets revealed that localized irradiation dramatically altered the gut microbial composition, resulting in a decrease ratio of Bacteroidetes to Firmicutes. …”

Effect of different light conditions on the growth response of sugar beet to NaCl by Ryota Obama (20179531)

The association between body mass index and pathological complete response in neoadjuvant-treated breast cancer patients by Ida Skarping (8203665)

Comparison of endoplasmic reticulum stress and mitochondrial biogenesis responses after 12 weeks of treadmill running and ladder climbing exercises in the cardiac muscle of middle-... by Kijin Kim (6513578)

DCAF13 promotes triple-negative breast cancer metastasis by mediating DTX3 mRNA degradation by Jiazhe Liu (9754115)

Table_1_Alterations of the Gut Microbiome Composition and Lipid Metabolic Profile in Radiation Enteritis.xlsx by Yiyi Li (1968925)

“…During RE activity, the intestinal inflammation of the mice was confirmed by typical signs, symptoms, imaging findings and pathological evidences. 16S datasets revealed that localized irradiation dramatically altered the gut microbial composition, resulting in a decrease ratio of Bacteroidetes to Firmicutes. …”