DataSheet1_“Tranq-dope” overdose and mortality: lethality induced by fentanyl and xylazine.DOCX by Mark A. Smith (21079)

“…Notably, a nonlethal dose of xylazine (100 mg/kg) produced an approximately 100-fold decrease in the estimated LD₅₀ for fentanyl. …”

Up-regulation of <i>Ssdp</i> results in alteration in transcriptomics in <i>Drosophila</i> head. by Safa Salim (9186786)

“…For the qRT-PCR experiments, data are shown as mean (red horizontal line). Each black dot is a data point representing an independent biological replicate with 20 individual fly heads per biological replicate. …”

A Novel Gene, <em>fudoh,</em> in the SCC<em>mec</em> Region Suppresses the Colony Spreading Ability and Virulence of <em>Staphylococcus aureus</em> by Chikara Kaito (230958)

“…MRSA strains with high spreading ability (27%) had no <em>fudoh</em> or a point-mutated <em>fudoh</em> that did not suppress colony spreading. …”

Image_4_Group ICA of wide-field calcium imaging data reveals the retrosplenial cortex as a major contributor to cortical activity during anesthesia.jpg by Alessandro Scaglione (10810689)

Image_5_Group ICA of wide-field calcium imaging data reveals the retrosplenial cortex as a major contributor to cortical activity during anesthesia.jpg by Alessandro Scaglione (10810689)

Data_Sheet_1_Ramadan diurnal intermittent fasting is associated with significant plasma metabolomics changes in subjects with overweight and obesity: A prospective cohort study.xls... by Mohamed Madkour (4837197)

“…The metabolomic assay was performed using liquid chromatography-mass spectrometry for the two-time points.</p>Results and discussion<p>Metabolomics assay revealed a significant reduction in a few metabolites. …”

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx by Yang Yang (45629)

“…The prevalence of depressive symptoms decreased with the adoption of more favorable lifestyle categories, with the lowest likelihood observed among individuals with a favorable lifestyle (0.35 [0.30–0.41]). …”

Zinc toxicity to Daphnia magna in a two-species microcosm can be predicted from single-species test data: the effects of phosphorus supply and pH by Andreas Fettweis (5153576)

“…The 21-day daphnid population size was considerably reduced by increased Zn and by decreased P supply with a significant (p<0.001) interaction among both factors. …”

Table_1_Association between the RETN -420C/G polymorphism and type 2 diabetes mellitus susceptibility: A meta-analysis of 23 studies.docx by Fei Luo (289384)

“…Meta-regression found that the median age of T2DM participants (using age 50 as the cutoff) could be a factor in the observed variation. …”

Data_Sheet_1_Responses of Woody Plant Functional Traits to Nitrogen Addition: A Meta-Analysis of Leaf Economics, Gas Exchange, and Hydraulic Traits.PDF by Hongxia Zhang (164388)

“…For plant hydraulics, N addition significantly increased vessel diameter (+7.0%), hydraulic conductance in stems/shoots (+6.7%), and water potential corresponding to 50% loss of hydraulic conductivity (P₅₀, +21.5%; i.e., P₅₀ became less negative), while water potential in leaves (−6.7%) decreased (became more negative). …”

Datasheet1_Potential chemoprotective effects of active ingredients in Salvia miltiorrhiza on doxorubicin-induced cardiotoxicity: a systematic review of in vitro and in vivo studies... by Qingqing Wang (141110)

“…The quality scores of included studies ranged from 4 to 7 points (a total of 10 points), according to SYRCLE's risk of bias tool.…”

DataSheet_1_Opposite trends in incidence of breast cancer in young and old female cohorts in Hungary and the impact of the Covid-19 pandemic: a nationwide study between 2011–2020.x... by Zoltán Kiss (5570003)

“…</p>Conclusion<p>The incidence of breast cancer significantly decreased in older age groups (≥50 years), oppositely increased among young females between 2011 and 2019, while cause-specific mortality in breast cancer patients showed a non-significant decrease. …”

Clinical-epidemiological characteristics associated with discharge outcomes and seasonality among surviving patients with Guillain-Barré syndrome in a national third-level hospital... by Victor Velásquez-Rimachi (10798456)

“…We defined the discharge results as an improvement if the HSS score decreased by at least one point from admission to hospital discharge and defined hospital stay as prolonged if > 14 days. …”

Polymorphisms in the CIITA −168A/G (rs3087456) and CIITA +1614G/C (rs4774) may influence severity in multiple sclerosis patients by Valéria Coelho Santa Rita Pereira (6570740)

“…Although less significant, the CIITA +1614 GC also pointed to a less severe MS course and the chance of the patient progressing to MSSS3 decreased 79% (p = 0.015). …”

The mean number of clusters per feature for <i>q</i> = 5 (left) and <i>q</i> = 7 (right) for different values of the agreement threshold <i>a</i>. by Pádraig MacCarron (8921690)

Effect of trauma/HS without or with IL-6 treatment on cardiac apoptosis-related gene expression; impact of Stat3 inhibition on the IL-6 effect. by Jeffrey A. Alten (80715)

“…Red indicates a level of expression above the mean expression of a gene within the experiment. …”

Image3_Identification of two novel ferroptosis-associated targets in sepsis-induced cardiac injury: Hmox1 and Slc7a11.tif by Yushun Xu (16428834)

“…GSEA enrichment analysis demonstrated that ferroptosis pathway Z-score rapidly increased in the first 24 h and decreased gradually in the following 24–72 h. Fuzzy analysis was then used to obtain distinct clusters of temporal patterns and find genes in cluster 4 that exhibited the same trend with ferroptosis progression during the time points. …”

Image2_Identification of two novel ferroptosis-associated targets in sepsis-induced cardiac injury: Hmox1 and Slc7a11.tif by Yushun Xu (16428834)

“…GSEA enrichment analysis demonstrated that ferroptosis pathway Z-score rapidly increased in the first 24 h and decreased gradually in the following 24–72 h. Fuzzy analysis was then used to obtain distinct clusters of temporal patterns and find genes in cluster 4 that exhibited the same trend with ferroptosis progression during the time points. …”

Datasheet2_Identification of two novel ferroptosis-associated targets in sepsis-induced cardiac injury: Hmox1 and Slc7a11.zip by Yushun Xu (16428834)

“…GSEA enrichment analysis demonstrated that ferroptosis pathway Z-score rapidly increased in the first 24 h and decreased gradually in the following 24–72 h. Fuzzy analysis was then used to obtain distinct clusters of temporal patterns and find genes in cluster 4 that exhibited the same trend with ferroptosis progression during the time points. …”

Datasheet1_Identification of two novel ferroptosis-associated targets in sepsis-induced cardiac injury: Hmox1 and Slc7a11.zip by Yushun Xu (16428834)

“…GSEA enrichment analysis demonstrated that ferroptosis pathway Z-score rapidly increased in the first 24 h and decreased gradually in the following 24–72 h. Fuzzy analysis was then used to obtain distinct clusters of temporal patterns and find genes in cluster 4 that exhibited the same trend with ferroptosis progression during the time points. …”