DataSheet_1_Anti-diabetic combination therapy with pioglitazone or glimepiride added to metformin on the AGE-RAGE axis: a randomized prospective study.pdf by Eugenio Ragazzi (2211859)

“…Within pioglitazone group, as well within glimepiride group, significant variations (Δ, as difference between 5 years of treatment minus basal) were observed for AGE (Δ= ˗21.1±13.4 µg/ml, P<0.001 for pioglitazone; Δ= ˗14.4±11.4 µg/ml, P<0.001 for glimepiride) and in AGE/s-RAGE (Δ= -0.037±0.022 µg/pg, P<0.001 for pioglitazone; Δ= -0.024±0.020µg/pg, P<0.001 for glimepiride), suggesting an average decrease of the parameters by more than 50% in both treatments. …”

Image_3_Cardioprotective Effects and Possible Mechanisms of Luteolin for Myocardial Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Evidence.TIF by Qinyuan Pan (11589910)

Image_2_Effects of Quercetin Glycoside Supplementation Combined With Low-Intensity Resistance Training on Muscle Quantity and Stiffness: A Randomized, Controlled Trial.TIF by Yuta Otsuka (187165)

“…Objective<p>Aging of skeletal muscle is characterized not only by a decrease of muscle quantity but also by changes in muscle quality, such as an increase in muscle stiffness. …”

Image_2_Cardioprotective Effects and Possible Mechanisms of Luteolin for Myocardial Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Evidence.TIF by Qinyuan Pan (11589910)

Image_6_Cardioprotective Effects and Possible Mechanisms of Luteolin for Myocardial Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Evidence.TIF by Qinyuan Pan (11589910)

Image_1_Effects of Quercetin Glycoside Supplementation Combined With Low-Intensity Resistance Training on Muscle Quantity and Stiffness: A Randomized, Controlled Trial.TIF by Yuta Otsuka (187165)

“…Objective<p>Aging of skeletal muscle is characterized not only by a decrease of muscle quantity but also by changes in muscle quality, such as an increase in muscle stiffness. …”

Image_5_Cardioprotective Effects and Possible Mechanisms of Luteolin for Myocardial Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Evidence.TIF by Qinyuan Pan (11589910)

This study examines a range of drugs targeting different cellular functions in three bacterial species, using various system-level readouts to analyze their effects. by Morten Kals (19727515)

“…This novel link between morphology change and growth inhibition led us to develop a new heuristic metric, MOR₅₀, which can be used for rapid and high throughput MIC estimation. …”

Image_1_Effects of Quercetin Glycoside Supplementation Combined With Low-Intensity Resistance Training on Muscle Quantity and Stiffness: A Randomized, Controlled Trial.TIF by Yuta Otsuka (187165)

“…Objective<p>Aging of skeletal muscle is characterized not only by a decrease of muscle quantity but also by changes in muscle quality, such as an increase in muscle stiffness. …”

Combined M002 and irradiation to neuroblastoma xenografts. by Lauren A. Gillory (469462)

“…Tumor volumes were measured twice weekly and reported as fold change in tumor volume ± standard error. There was a significant decrease in tumor volume in the animals treated with combined modalities for both tumor types (<b>A</b> and <b>C</b>). …”

AXL overexpression dampens the response to IFNα. by Scott A. Read (788751)

“…<p>Stable transfection of Huh-7 cells with PCMV6-AXL was confirmed by western blot, using antibodies against AXL or the fusion Myc tag (A). Huh-7 cells overexpressing AXL induced a stronger but more transient phosphorylation of STAT1 (B), with increased phosphorylation at 15 and 30 minutes post-IFN (50 u/ml), but a strong decrease at 1 h (2 replicates). …”

RNA degrades with time. by Jeffrey A. Blair (3178230)

“…(C) An antibody to rRNA shows a similar decrease of immunoreactivity with time, (D) but an antibody to dsDNA remains robust even after a PMI of 46 h. …”

Supplementary Material for: Nephritis-Associated Plasmin Receptor-Positive Post-Streptococcal Acute Glomerulonephritis Showing Full-House Pattern: A Case Report by figshare admin karger (2628495)

“…Introduction: Post-streptococcal acute glomerulonephritis (PSAGN) is a disease in which patients develop hematuria and leg edema following streptococcal infection, which may lead to acute nephritic syndrome and nephrotic syndrome. …”

Table_7_Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome.xlsx by Yaseswini Neelamraju (4509259)

DataSheet1_Techno-Economic and Environmental Assessment of Ammonia Production From Residual Bagasse Gasification: A Decarbonization Pathway for Nitrogen Fertilizers.pdf by Rodrigo Oliveira Telini (12874529)

“…Finally, since 1.6 Mt_CO2/y can be avoided by using the residual bagasse as feedstock in the ammonia plant, the alternative scenarios become competitive vis-à-vis the conventional scenario in terms of NPV when carbon taxes of 40–50 USD/t_CO2 are adopted. …”

Table_1_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Table_2_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Table_1_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

Table_2_Small RNA AvrA Regulates IscR to Increase the Stress Tolerances in SmpB Deficiency of Aeromonas veronii.XLSX by Dan Wang (34472)

“…Transcriptomic data revealed that expressions of the type IV pilus assembly and type VI secretion system (T6SS) proteins were downregulated in SmpB deficiency, indicating that the virulence of A. veronii might be attenuated. Although SmpB deletion decreased colonization in the mouse spleen and liver, LD50 of the smpB mutant was not altered as expected, compared with the wild type. …”

DataSheet1_Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis.docx by Jongsung Hahn (6707927)

“…Compared to opioid therapy, dizziness, cognitive dysfunction, and respiratory depression in combination therapy significantly increased in non-RCTs (OR 3.26, 95% CI 1.82–5.85; OR 3.13, 95% CI 1.51–6.50; OR 1.71, 95% CI 1.31–2.24, respectively), and a similar trend for dizziness and cognitive dysfunction was also identified in the RCT analysis, although the difference was not significant. …”