Identification of a Negative Allosteric Site on Human α4β2 and α3β4 Neuronal Nicotinic Acetylcholine Receptors by Ryan E. Pavlovicz (205761)

“…The T58K mutation resulted in an eight-fold decrease in the potency of KAB-18, a compound that exhibits preferential antagonism for human α4β2 over α3β4 nAChRs, while the F118L mutation resulted in a loss of inhibitory activity for KAB-18 at concentrations up to 100 µM. …”

Image 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf by Liang Sui (20912441)

“…Joinpoint regression analysis revealed fluctuating trends in prevalence and incidence with periods of increase and decline, and a general decrease in mortality except during brief intervals. …”

Presentation 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf by Liang Sui (20912441)

“…Joinpoint regression analysis revealed fluctuating trends in prevalence and incidence with periods of increase and decline, and a general decrease in mortality except during brief intervals. …”

Visualization of model results for tumour cell density, blood vessel density, and oxygen partial pressure over a 30 day span with no treatment. by Cameron Meaney (6894080)

“…<p>Model is solved using the FEniCS Project Finite Element Solver [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007926#pcbi.1007926.ref055" target="_blank">55</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007926#pcbi.1007926.ref056" target="_blank">56</a>] and is visualized in Paraview [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007926#pcbi.1007926.ref057" target="_blank">57</a>]. …”

PTSD symptom changes during Trauma-Focused Cognitive Behavioural Therapy (TF-CBT) in children and adolescents: a Single-Case Experimental Design study by Lieke H. Kooij (12895939)

“…However, symptoms do not decrease in a clear line, and individual symptom fluctuations are common.…”

Table_2_The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach.docx by Carl-Fredrik Johnzon (5445557)

“…In plasma, significant reductions in ketone bodies (3-hydroxybutyrate and acetoacetate) and decreased levels of short-chain fatty acids, known to be major products released from the gut microbiota, were observed after LPS infusion; a profound reduction of plasma citrate was also seen. …”

Data_Sheet_1_Modafinil’s effects on cognition and sleep quality in affectively-stable patients with bipolar disorder: a pilot study.pdf by Jessica M. Lipschitz (16927743)

“…</p>Methods<p>Twelve individuals with affectively-stable BD were recruited and randomized to a flexible dose of modafinil (100 to 200 mg/day) or placebo, adjunctive to a therapeutic dose of a mood stabilizer. …”

Image_1_Distinctive Community Patterns With Exceptional Diversity of Polychaetes Around a Tectonically Active Archipelago in the Tropical Indian Ocean.TIF by Aiswarya Gopal (8296260)

“…This paper examines the distribution and standing stock of macrozoobenthos at 50, 100, and 200 m depth contours surrounding the Andaman and Nicobar archipelago in the tropical Indian Ocean. …”

Table 1_Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.docx by Junjie Liu (193511)

“…Donor sperm was linked to better clinical pregnancy rates (RR 1.27, 95% CI 1.08–1.48) and decreased incidences of biochemical pregnancy (RR 0.85, 95% CI 0.81–0.88), miscarriage (RR 0.91, 95% CI 0.84–1.00), very preterm birth (RR 0.88, 95% CI 0.80–0.96), and very low birth weight (RR 0.89, 95% CI 0.81–0.98) compared with partner sperm. …”

Table_1_The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach.DOCX by Carl-Fredrik Johnzon (5445557)

“…In plasma, significant reductions in ketone bodies (3-hydroxybutyrate and acetoacetate) and decreased levels of short-chain fatty acids, known to be major products released from the gut microbiota, were observed after LPS infusion; a profound reduction of plasma citrate was also seen. …”

Data Sheet 1_Response of alfalfa growth and rhizosphere properties to soil phosphorus supply and mowing in a salt-affected soil.docx by Junjie Tian (5738408)

“…Introduction<p>Phosphorus (P) deficiency is a key limiting factor for alfalfa quality and yield in salt- affected soils, and root exudates are considered as a strategy for alfalfa P acquisition under P stress, which requires the supply of photosynthetic products.However, mowing may reduce the supply of photosynthetic products by decreasing photosynthetic rate and chlorophyll yield, which can affect the concentration of alfalfa root exudates in saline soil. …”

Rare CNVs in Suicide Attempt include Schizophrenia-Associated Loci and Neurodevelopmental Genes: A Pilot Genome-Wide and Family-Based Study by Marcus Sokolowski (3605534)

“…Overall, 45 SA had CNVs enriched for 65 medically relevant genes previously shown to be affected by CNVs, which were characterized by a neurodevelopmental biology. A neurodevelopmental implication was partly congruent with our previous SNP-based GWAS, but follow-up analysis here indicated that carriers of rare CNVs had a decreased burden of common SNP risk-alleles compared to non-carriers. …”

Opposite regulation of <i>chd</i> by <i>hairy2a</i> or <i>braEnR</i> depending on the D by Cecilia E. Aguirre (287180)

“…<i>Chd</i> expression decreased in 88% or 100% of dorsalised embryos that were injected with 1 ng of <i>braEnR</i> (<i>braEnR</i>/LiCl; n = 41) or of <i>hairy2a</i> mRNAs (<i>hairy2a</i>/LiCl, n = 23), respectively.…”

Data_Sheet_1_Association of the Composite dietary antioxidant index with all-cause and cardiovascular mortality: A prospective cohort study.doc by Lei Wang (6656)

“…</p>Conclusion<p>A high CDAI was linked to decreased all-cause and cardiovascular mortality risk. …”

Table_1_Distinctive Community Patterns With Exceptional Diversity of Polychaetes Around a Tectonically Active Archipelago in the Tropical Indian Ocean.docx by Aiswarya Gopal (8296260)

“…This paper examines the distribution and standing stock of macrozoobenthos at 50, 100, and 200 m depth contours surrounding the Andaman and Nicobar archipelago in the tropical Indian Ocean. …”

ERR2/3 may in part operate through <i>Kcna10</i> to promote a gamma motor neuron-like biophysical signature. by Mudassar N. Khan (14290428)

“…<b>(C)</b> Reporter tdTomato fluorescence driven by wild-type (WT) <i>Kcna10</i> promoter is boosted by ERR2 cotransfection (red, <i>n</i> = 102) in chick motor neurons when compared to control (gray, <i>n</i> = 100) and decrease in tdTomato reporter fluorescence upon mutating the ERR2/3 binding sites (black, <i>n</i> = 101). …”

DataSheet1_Inverse Design of Local Solar Flux Distribution for a Solar Methanol Reforming Reactor Based on Shape Optimization.DOCX by Xinyuan Tang (12960584)

“…The gradient-based segmentation method is applied to convert the continuous solar flux into step-like flux to guide the concentrator system design. …”

Germination Ecology of Ivy-Leaved Morning-Glory: an Invasive Weed in Soybean Fields, Iran by A. SIAHMARGUEE (8743458)

“…However, the results showed that high temperature pretreatment >100 oC decreased seed germination. Germination decreased from 82 to 3% as temperature increased from 100 to 130 oC. …”

Table_1_Characteristics of second primary breast cancer after ovarian cancer: a Korea central cancer registry retrospective study.docx by Eun-Gyeong Lee (627417)

“…Based on the age-standardized rate (ASR), the incidence of SPBC after OC was 293.58 per 100,000 ovarian cancer patients and the incidence of PBC was 39.13 per 100,000 women. …”

Table_1_Ataxia with oculomotor apraxia type 2 caused by a novel homozygous mutation in SETX gene, and literature review.DOCX by Shuaishuai Chen (7275431)

“…She had elevated AFP, increased serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and decreased anti-Müllerian hormone (AMH) levels. We identified a novel homozygous missense mutation of the SETX gene, c.7118 C>T (p. …”