Density dependent growth modulates time-to-threshold and optimal antibiotic treatment for in-vitro growth model. by Jason Karslake (3233934)

“…Small inset: Fraction decrease in the population as a function of for tigecycline (ε = 0.9). …”

Mechanisms involved in Sag-induced apoptosis. by Juliana Mundiñano (306020)

“…Data are expressed as the mean ± SD. *p<0.05. (E) Caspase-8 inhibitor decreases the loss of Δψm induced by SEB. …”

Effects of diabetes mellitus and systemic arterial hypertension on elderly patients' hearing, by Laurie Penha Rolim (6073727)

“…ANOVA and Kruskal-Wallis statistical tests were used, with a significance level set at 0.05. Results: When comparing the mean annual increase in the auditory thresholds of the A1 with the A2 assessment, considering each study group and its respective control, it can be observed that there was no statistically significant difference for any of the frequencies for the diabetes mellitus group; for the systemic arterial hypertension group, significant differences were observed after 4 kHz. …”

Stable inducible expression of various GFP-coilin proteins with endogenous coilin knockdown. by Zunamys I. Carrero (342815)

“…Rescue indicates that the induced protein increased proliferation in the coilin knockdown background, whereas decrease means the induced protein decreased proliferation rates lower than that found with coilin knockdown alone. …”

PINK1 expression alters mitochondrial function and cellular viability. by Anna Sandebring (263540)

“…Results are expressed as the mean number of cells with TMRM fluorescence above threshold set by depolarizing one set of cells with CCCP (100 µM, 10 minutes; see Supplementary <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005701#pone.0005701.s001" target="_blank">Fig. …”

PRE, W3, and W6 VL biopsy contractile protein per muscle fiber assessed through phalloidin-AF488 staining. by Cody T. Haun (4183900)

“…This metric was not significantly altered throughout the intervention (panel a). Phalloidin pixel intensity per fiber per μm², which represents actin content corrected for fCSA, demonstrated numerical but non-significant decreases from PRE to W3 and W6 (panel b), although the removal of subject 17 (statistical outlier) indicated a significant decrease occurred from PRE to W6. …”

Glyphosate Resistance Affect the Physiological Quality of Conyza bonariensis seeds by C. PIASECKI (5054501)

“…Seed analyses were performed in a completely randomized design with ten replications of 100 seeds each (1,000 seeds per biotype). …”

Interplay of basolateral K⁺ channels and the Na⁺/K⁺-ATPase. by Alexandra Erb (588278)

“…<b>B</b>) After permeabilisation with nystatin, lidocaine (1 mM) was applied to the basolateral bath. This resulted in a decrease of the I_SC from 17.20±2.58 µA/cm² to 12.00±1.67 µA/cm² (n = 5, N = 5, p≤0.05). …”

HOXA2 control of target enhancers. by Laure Bridoux (481118)

“…Co-translation of HOXA2 with PBX/MEIS gives rise to a stronger trimeric complex relative to HOXA3 and, accordingly, to a decrease in PBX-MEIS binding as a dimer (black arrow; see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009162#pgen.1009162.s003" target="_blank">S3G Fig</a> for quantification). …”

Excitation-Transcription (E-T) coupling is altered in dystrophic muscle fibers. by Denisse Valladares (489234)

“…<p>(A) In triad fractions obtained from normal and dystrophic muscles we observed a decrease in the expression of Cav1.1 (antibody against α1 s subunit) and an increase in the expression of Panx1, P2Y2 and P2Y1 in dystrophic compared to normal (n = 4). …”

ER stress reduces AKT phosphorylation at Thr308, but increases it at Ser473, and alters target substrate specificity. by Hong Wa Yung (227056)

“…<b>D</b>) Normalisation between phosphorylated AKT and AKT indicates an increase of Ser473 phosphorylation but a decrease at Thr308.</p>…”

The relative contribution of the different positions in DR2 to the transcriptional strength of P₄ promoter. by Ilia Belotserkovsky (257415)

“…Substitutions of the indicated nucleotides with cytosine or guanine, and increase or decrease of the spacer size by a single nucleotide, were achieved by site-directed mutageneses that were performed on the p<i>P₄-gfp</i> plasmid (see “<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000651#s4" target="_blank">Materials and Methods</a>”). …”

SipC-mediated invasion occurs independently of cellular Rho GTPases. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

Foxm1 expression during heart development. by Craig Bolte (299486)

“…Mean±SEM was determined from 5 random sections at E14.5 and P7 with 3 hearts in each group. qRT-PCR of total heart RNA demonstrated a decrease in Foxm1 mRNA from E14.5 to P20 and Foxm1 mRNA was undetectable in the adult heart (R). …”

Potential biomarkers detected by NMR and MS, metabolic pathways, as well as fold changes between different groups (<i>n</i> = 6). by Ze-Yun Li (704816)

“…The ratio over 1.00 indicated an increase, while ratio less than 1.00 indicated a decrease. …”

cAMP dynamics in adult mouse ventricular Epac1-camps expressing cardiomyocytes upon treatment with cAMP elevating agents and PDE4 inhibition. by Julia U. Sprenger (3387719)

“…<b>(C)</b> Representative FRET traces from Epac1-camps cardiomyocytes stimulated with the β-AR agonist isoproterenol (ISO, 100 nM) or <b>(E)</b> with the direct AC activator forskolin (10 μM) leading to an increase of cAMP visualized as a decrease in the FRET ratio. …”

Effect of JNK3-N-Tat on MPP⁺/MPTP-induced neuronal death in PD models. by Jing Pan (95938)

“…Representative images from immunostained sections of the SNc and the striatum from the sham-treated normal control group (i), the group of mice administered saline prior to MPP⁺ treatment (ii), and the groups of mice administered JNK3-N-Tat (iii) or JNK3-4A-Tat (iv) preceding MPTP injection. The results revealed that treatment with JNK3-N-Tat caused a significant decrease in neurodegeneration in the SNc and also attenuated MPTP-induced striatal DA terminal loss, whereas treatment with JNK3-4A-Tat had no effect. …”

miR-27b regulates ASC-mediated suppression of CFSE-labeled allogeneic CD4⁺ T cell proliferation. by Kuang-Den Chen (322973)

“…The cells were then cultured with Con A (1 µg/ml) (as 100% proliferation) and Con A + with different ratios of ASCs (1∶10, 1∶5, 1∶1, ASCs:T cells) with α-miR-27b or α-miRNC transfection. …”

Elf5 can regulate colony forming abilities of epidermal and hair follicle stem cells. by Anhua Hu (4805145)

“…(<b>c,f</b>) Quantification of colonies formed after modulation of Elf5 functions in epidermal SCs leads to a significant reduction in size (>100μm, shElf5). …”

Altered photoreceptor fate specification in TET mutant retinas. Related to Fig 3. by Ismael Hernández-Núñez (10128242)

“…Results display the mean + SEM for <i>n</i> = 3 for each genotype. Statistics are the result of One-way ANOVA followed by a Tukey’s comparisons test * <i>p</i> < 0.05; ** <i>p</i> < 0.01. …”