ET-1 upregulated MMP-1 and MMP-13 expression and downregulated TIMP-1 release. by Wei Yuan (64653)

“…<p>Confluent CECs in six-well plates were cultured in serum-free medium for 12 hours and then treated with ET-1 (0–100 nM) for 36 hours. ET-1 increased the release of MMP-1 and MMP-13, but decreased the production of TIMP-1 in a dose-dependent pattern as shown by ELISA assay. …”

Analysis of sugars and chlorogenic acid in coffee harvested at different ripening stages and after processing by Rogéria Assis dos Santos (5910980)

“…During the roasting process and elaboration of the beverage, a reduction in the 5-CQA contents occurred. The levels of the isomers 3 and 4 showed no defined tendency to increase or decrease during processing. …”

Effect of ACE inhibitors on the comparative rates of ZPHL and HHL hydrolysis by blood ACE bound by mAbs on the plate. by Maxim N. Petrov (118931)

“…Effect of enalaprilat (100 nM – <b>B</b>) and teprotide (1 µM – <b>C</b>) on ZPHL/HHL ratio determined for ACE bound with each mAb. * - p<0.05 in comparison with mean values for samples without ACE inhibitors. …”

Actin destabilization counteracts ectocytosis defects in CCDC66-depletion. by Jovana Deretic (13113617)

“…<b>(C)</b> Cilia length was quantified in 3D according to ARL13b signal (co-localizing with acetylated-tubulin). The mean cilia length in CCDC66-depleted cells decreased to 0.74-fold compared to the mean control length at 0 h. …”

Differential -/-WT and -/-C3S expression profiling reveals genes acutely responsive to Stat3 oxidation. by Michela Grillo (9866772)

“…<p><b>A)</b> RNA isolated from MEFs untreated (-), treated with 10 ng ml^-1 LIF for 30 mins and/or 100 μM H₂O₂ for 1 h (+) was enriched for mRNA and analysed for <i>Socs3</i> and <i>Hbs1l</i> expression by qRT-PCR. …”

Supplementary Material for: Meta-analysis of the efficacy and safety of finerenone in diabetic kidney disease by Zheng Y. (4132180)

“…Analysis results demonstrated that patients receiving finerenone showed a significant decrease in changing urinary albumin-to-creatinine ratio (UACR) from baseline (MD: ﹣0.30; 95%CI [﹣0.33, ﹣0.27] P=0.46, I2=0%) (P＜0.05). …”

Interaction of FKBP8 with ER specific protein and FKBP8 expression in mitochondria fraction during mitophagy. by Michael O. Isei (20500908)

“…<p>Dual staining for FKBP8 (red) and BiP/GrP78 (green) was performed to analyze their colocalization in unstressed cells <b>(A)</b> and cells induced for mitophagy with PQ for 6 h <b>(B)</b>. …”

Densitometries of dynamic lung computed tomography (CT) by Hermann Wrigge (15630)

“…Histograms show the normalized lung volume for Hounsfield units ranging from -1,000 to 100, plotted as means of all animals. Aeration categories (hyperinflated, normally aerated, poorly aerated, nonaerated; see text for details) are marked. …”

Synergy between GPER1 and n-3 PUFAs in increasing MCF-7 cell cAMP-PKA signaling. by WenQing Cao (107805)

“…<b>E</b>, a PKA inhibitor, KT5720 (100 nM), reduced the inhibitory effect of E2 on n-3 PUFA-treated T47D cell colony formation (n = 2). …”

Table1_Changes in the global burden of foreign body aspiration among under-5 children from 1990 to 2019.xls by Yuying Wu (647826)

“…Many European countries (such as Italy, Netherlands, Iceland, etc.) showed a high incidence rate, but did not cause a large disease burden (DALYs all less than 200 per 100,000). …”

Image1_Changes in the global burden of foreign body aspiration among under-5 children from 1990 to 2019.pdf by Yuying Wu (647826)

“…Many European countries (such as Italy, Netherlands, Iceland, etc.) showed a high incidence rate, but did not cause a large disease burden (DALYs all less than 200 per 100,000). …”

Effect of plate washing on the dissociation of ACE inhibitor from ACE. by Sergei M. Danilov (118956)

“…The ZPHL/HHL ratio for ACE in solution in the presence of the inhibitor (red bar in the right column) is shown for comparison. Data are expressed as a % of control (i.e. ACE without inhibitor) and presented as a mean of at least 3 independent experiments. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Search results of kinetic parameter space and prediction of MdmX effect. by Sohyoung Kim (253617)

“…</p>c<p>The presence of MdmX (upto 100 fold k15) decreased maximum value (peak of oscillations) by >30%.…”

Fis1ΔTM membrane binding requires negatively charged lipids. by Robert C. Wells (348960)

“…Each panel depicted as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021384#pone-0021384-g001" target="_blank">Figure 1</a> with experiments done in a similar manner with 5 µM protein incubated for 4 hours at 25°C with 2 mM of 100 nm lipid vesicles (1∶400 protein∶lipid). …”

Light microscopic photographs of representative pan-leukocyte marker CD45 immunohistochemistry as well as Periodic acid-Schiff (PAS) and Oil Red O staining of liver sections. by Mohammed Shaqura (4451848)

“…<b>D-F</b>) show that the glycogen granules of the hepatic cells as examined in PAS-stained sections of liver showed a significant decrease in glycogen granules in ACF rats (78.8±3.8) compared to control (100±2.8)(p<0.05, Student t-test). …”

Correlation of data obtained from RCM and SIM reflectance. by Emily J. Guggenheim (1928215)

“…The percentage of ‘regions’ or ‘connected components’ visualised with each modality, RCM and R-SIM, that are also seen in the other modality (54% and 74% respectively), were computed automatically using MATLAB as detailed in the methods section using 27 cells from multiple experiments performed on separate days (H). The means and STD are plotted. Comparison of the size distribution of the FWHM of 100 / 125 regions for RCM and R-SIM respectively are shown (I), with a fitted probability density function.…”

Homolog pairing and sister chromatid cohesion in interphase remain unaffected genome-wide after knockdown of Rad21. by T. Niroshini Senaratne (3067776)

“…A simple separation of sister chromatids would be expected to cause a decrease in the percentage of nuclei with a single FISH signal, or an increase in the area of FISH signals; we observed neither (see main text for details).…”

Acclimatization of Photosynthetic Apparatus of Tor Grass (<i>Brachypodium pinnatum</i>) during Expansion by Wojciech Bąba (2825267)

“…Twelve populations differentiated by age: young (30–50 years old), intermediate age (ca. 100 y) and old (>300 y) were studied. It was confirmed that the decrease of the number of genotypes as a result of environmental stress and competition were reflected in changes in chlorophyll fluorescence (ChlF) parameters. …”