Table5_Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone.XLSX by Hagar A. Morgaan (15350347)

“…The latter effects disappeared in LPS/PE preparations, suggesting a postconditioning action for LPS against renal manifestation of PE. …”

Synthesis and Magnetism of Neutral, Linear Metallocene Complexes of Terbium(II) and Dysprosium(II) by Colin A. Gould (7208942)

“…The impact of this effect is most notably evident for Tb­(Cp^iPr5)₂, which displays an effective thermal barrier to magnetic relaxation of 1205 cm^–1 and a 100-s blocking temperature of 52 K, the highest values yet observed for any nondysprosium single-molecule magnet.…”

Kidney-Specific Reduction of Oxidative Phosphorylation Genes Derived from Spontaneously Hypertensive Rat by Jason A. Collett (787818)

“…We hypothesize that renal Mt-genes derived from female spontaneously hypertensive rats (SHR) that exhibit hypertension have reduced expression specific to kidney cortex. After breeding a female Okamoto-Aoki SHR (SAP = 188mmHg) with Brown Norway (BN) males (SAP = 100 and 104 mmHg), hypertensive female progeny were backcrossed with founder BN for 5 consecutive generations in order to maintain the SHR mitochondrial genome in offspring that contain over increasing BN nuclear genome. …”

Population pharmacokinetic analysis of acetaminophen overdose with immediate release, extended release and modified release formulations by Daniel A. Spyker (13801998)

“…</p> <p>Acetaminophen ER and MR formulations have slower absorption and decreased bioavailability leading to a lower <i>C</i>_max and later <i>T</i>_max than the IR formulation. …”

Table_1_Procedural and Methodological Quality in Preclinical Stroke Research–A Cohort Analysis of the Rat MCAO Model Comparing Periods Before and After the Publication of STAIR/ARR... by Jacqueline Friedrich (12687338)

“…From the years 2009 and 2019, 100 published articles each using a rat stroke model were analyzed to quantify parameters related to anesthesia, physiological monitoring, stroke model type, ischemia verification, and overall study quality over time. …”

Data_Sheet_1_Promoting the Quality of Teacher-Toddler Interactions: A Randomized Controlled Trial of “Thrive by Three” In-Service Professional Development in 187 Norwegian Toddler... by Elisabet Solheim Buøen (11722910)

“…Eighty childcare centers with 187 toddler classrooms in Norway were randomly assigned to either the Thrive by Three intervention group (n=87) or a usual-activity wait list control group (n=100). …”

Morphology and cell viability in U-87MG, U-251MG, SHSY5Y and N2a cells after treatment with SLCP, BBR and SLCP+BBR. by Panchanan Maiti (1459852)

“…<b>B-C:</b> Cell viability was decreased in both the cell lines in a dose-dependent manner after treatment with SLCP, BBR or SLCP + BBR. …”

DataSheet_1_Patients With Chronic Hepatitis C Virus Infection Are at an Increased Risk of Colorectal Cancer: A Nationwide Population-Based Case-Control Study in Taiwan.doc by Fu-Hsiung Su (301644)

“…The CRC risk was slightly greater for women than for men. The risk decreased with age, with the aOR decreased from 2.26 (95% CI = 1.32–3.87, p = 0.003) in patients under 45 years old to 1.31 (95% CI = 1.10–1.55, p = 0.03) in patients aged 50–59, and 1.10 (95% CI = 1.00–1.22, p = 0.061) in patients aged over 70.…”

Data_Sheet_1_Pilot Study: Nutritional and Preclinical Safety Investigation of Fermented Hispidin-Enriched Sanghuangporus sanghuang Mycelia: A Promising Functional Food Material to... by I-Chen Li (171694)

“…Results showed that the nutritional analysis of GKSS including moisture, ash, crude lipid, crude protein, carbohydrate, and energy were found to be 2.4 ± 0.3%, 8.0 ± 2.5%, 1.7 ± 0.3%, 22.9 ± 1.2%, 65.1 ± 3.1%, and 367.1 ± 10.2 kcal/100 g respectively. In the 28-day repeated-dose oral toxicity study, only Sprague-Dawley male rats receiving 5 g/kg showed a slight decrease in feed consumption at week 3, but no associated clinical signs of toxicity or significant weight loss were observed. …”

Table_1_Effects of Aerobic, Resistance, and Combined Exercise Training on Psychiatric Symptom Severity and Related Health Measures in Adults Living With Schizophrenia: A Systematic... by Shannon S. D. Bredin (12056549)

“…Aerobic training had a significant decrease on Positive and Negative Syndrome Scale (PANSS) negative scores (ES −2.28, 95% CI −3.57 to −1.00; p = 0.0005) and PANSS general scores (ES −2.51, 95% CI −3.47 to −1.55; p < 0.00001). …”

Immunogenicity and Safety of the 13-Valent Pneumococcal Conjugate Vaccine <i>versus</i> the 23-Valent Polysaccharide Vaccine in Unvaccinated HIV-Infected Adults: A Pilot, Prospecti... by Francesca Lombardi (756146)

“…Overall, the proportion of subjects achieving seroprotection and seroconversion to all serotypes was comparable between groups. A marked decrease in IgG levels over time was observed with both vaccines. …”

Figure 2 from Methylation-Based ctDNA Tumor Fraction Changes Predict Long-Term Clinical Benefit From Immune Checkpoint Inhibitors in RADIOHEAD, a Real-World Pan-Cancer Study by Samantha I. Liang (22090961)

“…Log-rank test between groups: 100% vs. any decrease, <i>P</i> < 0.005; 80% decrease vs. any decrease, <i>P</i> = 0.01; 100% decrease vs. 80% decrease, <i>P</i> = 0.04; 100% decrease vs. any increase, <i>P</i> < 0.005; 80% decrease vs. any increase, <i>P</i> < 0.005; any decrease vs any increase, <i>P</i> < 0.005. c-index, concordance index.…”

Monocyte Recruitment to the Dermis and Differentiation to Dendritic Cells Increases the Targets for Dengue Virus Replication by Michael A. Schmid (638218)

“…Further, we show that ∼100-fold more hematopoietic cells in the dermis were DENV-infected compared to Langerhans cells in the epidermis. …”

Universal Actuator for Efficient Silencing of <i>Escherichia coli</i> Genes Based on Convergent Transcription Resistant to Rho-Dependent Termination by Alexander A. Krylov (8962193)

“…The maximal silencing folds achieved for <i>gltA</i>, <i>pgi</i>, and <i>ppc</i> were approximately 7, 11, and >100, respectively. …”

Patterning in Birthweight in India: Analysis of Maternal Recall and Health Card Data by Malavika A. Subramanyam (104709)

“…Children were less likely to be born with low birthweight if they had mothers with over 12 years of education compared to 1–5 years of education with relative risk (RR) of 0.79 (95% confidence interval [CI]: 0.52, 1.2) in the card sample and 0.70 (95% CI: 0.59, 0.84) in the recall sample. A 100 gram difference in a child's birthweight was associated with a decreased likelihood of underweight in both the card (RR: 0.95; 95% CI: 0.94, 0.96) and recall (RR: 0.96; 95% CI: 0.96, 0.97) samples.…”

miR-223 null macrophages have enhanced inflammatory signaling and increased FBXW7 levels. by Jeffrey A. Deiuliis (3331071)

“…<p>(A) Effect of LPS (100ng/ml) on mmu-miR-223 levels in the mouse macrophage cell line Raw264.7 and in primary mouse macrophages from C57BL/6J mice as measured by qPCR, relative to snoRNA234. …”

DataSheet1_New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors.PDF by Yaser A. Mostafa (12395014)

“…Introduction<p>We developed and produced a new series of 4,6-diaryl-pyrimidines 9–29 as antiproliferative agents targeting EGFR/VEGFR-2.…”

Measured time series from e-Rep circuit showing the period-1 LC (protein <i>A</i>-yellow, <i>B</i>-blue and <i>C</i>-purple). by Edward H. Hellen (346773)

“…<p>β = 0.1, α = 46, n = 3, <i>k</i>_S1 = 0.025, <i>k</i>_S0 = 1, and η = 1. (a) κ = 14, (b) κ = 19. Note that the protein oscillation amplitudes are larger in frame (a) than (b) since the vertical scale is 200 mV/div in (a) and 100 mV/div in (b). …”

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β₁-Adrenoceptor Identifies an Intramembrane Na⁺ Ion that Stabilises the Ligand-Free Receptor by Jennifer L. Miller-Gallacher (541986)

“…We have determined the structure of an ultra-thermostable β₁AR mutant bound to the weak partial agonist cyanopindolol to 2.1 Å resolution. High-quality crystals (100 μm plates) were grown in lipidic cubic phase without the assistance of a T4 lysozyme or BRIL fusion in cytoplasmic loop 3, which is commonly employed for GPCR crystallisation. …”

IAA application on <i>pin1</i> meristem leads to local tissue softening and pectin de-methyl-esterification in sub-epidermal tissues. by Siobhan A. Braybrook (388465)

“…Note that meristem curvature does not correlate with areas of decreased E_A, and that there is no bulging of the meristem accompanying decreased rigidity. …”