Table_1_Xiao-Shen-Formula, a Traditional Chinese Medicine, Improves Glomerular Hyper-Filtration in Diabetic Nephropathy via Inhibiting Arginase Activation and Heparanase Expression... by Xiaofei An (537917)

“…Studies were performed using control, diabetic DN, DN treated with XSF groups (1 g/kg/d, LXSF or 3 g/kg/d, HXSF) for 6 weeks and hGECs were post-treated with mice serum containing HXSF (MS-HXSF) and arginase inhibitor (ABH, 100 μM) in high glucose medium. HXSF treatment restored STZ-induced renal hyper-filtration, glomerulosclerosis, renal microvascular remodeling and the increased levels of systemic reactive oxidative species and inflammatory cytokines, accompanied by preventing the decreased expression of glomerular heparin sulfate and the increased levels of cortical heparanase and argianse2 protein and arginase activity. …”

Supplementary Material for: Efficacy of Rituximab for Minimal Change Disease and Focal Segmental Glomerulosclerosis with Frequently Relapsing or Steroid-Dependent Nephrotic Syndrom... by Lan L. (17388316)

“…The relapse frequency, calculated as the ratio of relapse times to follow-up years, significantly decreased after rituximab treatment [0.04 (0.00, 0.08) vs. 1.71 (1.00, 2.45), P < 0.001]. …”

Table_1_Medium-chain triglycerides (8:0 and 10:0) increase muscle mass and function in frail older adults: a combined data analysis of clinical trials.pdf by Osamu Ezaki (219242)

Table_2_Medium-chain triglycerides (8:0 and 10:0) increase muscle mass and function in frail older adults: a combined data analysis of clinical trials.pdf by Osamu Ezaki (219242)

Table 1_Durability of benralizumab effectiveness in severe eosinophilic asthma patients with and without chronic rhinosinusitis with nasal polyps: a post hoc analysis from the ANAN... by Luisa Brussino (6617354)

“…After 96 weeks of treatment, the annual exacerbation rate (AER) decreased in both groups, with CRSwNP patients achieving considerable reductions than No-CRSwNP patients (severe AER dropped by 100% and 95.6%, respectively). …”

Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip by Peixi Zhao (620068)

“…The global age-standardized rates per 100,000 were: prevalence 22.2 (19.8 - 24.8), deaths 0.2 (0.2 - 0.2), and DALYs 11.4 (9.8 - 13.2). …”

Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx by Peixi Zhao (620068)

“…The global age-standardized rates per 100,000 were: prevalence 22.2 (19.8 - 24.8), deaths 0.2 (0.2 - 0.2), and DALYs 11.4 (9.8 - 13.2). …”

Data Sheet 1_A population-based analysis of the global burden of epilepsy across all age groups (1990–2021): utilizing the Global Burden of Disease 2021 data.pdf by Ling-zhi Yang (20418434)

“…</p>Finding<p>In 2021, there were 24,220,856 (95% UI: 18,476,943–30,677,995) patients with epilepsy, with an age-standardized prevalence rate (ASPR) of 307.38 per 100,000 persons (95% UI: 234.71–389.02) and an age-standardized incidence rate (ASIR) of 42.821 per 100,000 persons (95% UI: 31.24–53.72).The global age-standardized mortality rate (ASMR) of epilepsy was 1.74 per 100,000 population (95% UI: 1.46–1.92); The age-standardized DALYs rate (ASDR) were 177.85 per 100,000 population (95% UI: 137.66–225.90); 154.25 per 100,000 population for females [114.73–201.76], and 201.29 per 100,000 population for males [157.93–252.74]. …”

Monocyte Recruitment to the Dermis and Differentiation to Dendritic Cells Increases the Targets for Dengue Virus Replication by Michael A. Schmid (638218)

“…Further, we show that ∼100-fold more hematopoietic cells in the dermis were DENV-infected compared to Langerhans cells in the epidermis. …”

Universal Actuator for Efficient Silencing of <i>Escherichia coli</i> Genes Based on Convergent Transcription Resistant to Rho-Dependent Termination by Alexander A. Krylov (8962193)

“…The maximal silencing folds achieved for <i>gltA</i>, <i>pgi</i>, and <i>ppc</i> were approximately 7, 11, and >100, respectively. …”

Patterning in Birthweight in India: Analysis of Maternal Recall and Health Card Data by Malavika A. Subramanyam (104709)

“…Children were less likely to be born with low birthweight if they had mothers with over 12 years of education compared to 1–5 years of education with relative risk (RR) of 0.79 (95% confidence interval [CI]: 0.52, 1.2) in the card sample and 0.70 (95% CI: 0.59, 0.84) in the recall sample. A 100 gram difference in a child's birthweight was associated with a decreased likelihood of underweight in both the card (RR: 0.95; 95% CI: 0.94, 0.96) and recall (RR: 0.96; 95% CI: 0.96, 0.97) samples.…”

miR-223 null macrophages have enhanced inflammatory signaling and increased FBXW7 levels. by Jeffrey A. Deiuliis (3331071)

“…<p>(A) Effect of LPS (100ng/ml) on mmu-miR-223 levels in the mouse macrophage cell line Raw264.7 and in primary mouse macrophages from C57BL/6J mice as measured by qPCR, relative to snoRNA234. …”

DataSheet1_New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors.PDF by Yaser A. Mostafa (12395014)

“…Introduction<p>We developed and produced a new series of 4,6-diaryl-pyrimidines 9–29 as antiproliferative agents targeting EGFR/VEGFR-2.…”

Table 1_The burden of gastric cancer attributed to high salt intake and predictions through the year 2042: a cross-national comparative analysis of China, Japan, and South Korea.do... by Wei Liu (20030)

“…Globally, ASMR decreased from 1.74 per 100,000 in 1990 to 0.89 per 100,000 in 2021 (EAPC = −2.26). …”

Data_Sheet_1_Response of Nitrate Processing to Bio-labile Dissolved Organic Matter Supply Under Variable Oxygen Conditions in a Sandy Beach Seepage Face.PDF by Shan Jiang (121292)

“…Compared with the active response of sediment microbiota to NO₃^– additions, the supply of glucose (approximately 300 μM final concentration added) did not significantly change the NO₃^– removal efficiency under aerobic conditions (dissolved oxygen saturation approximately 100%). Similarly, an insignificant increase of NO₃^– removal rate after glucose amendment of the circulating water was obtained when dissolved oxygen (DO) saturation decreased to approximately 70% in the input solution. …”

DataSheet_1_Spatiotemporal Trends in the Incidence of Gastrointestinal Neoplasms in Wuwei City of Northwestern China From 1995 to 2016: A Hospital-Based Retrospective Observational... by Kun Liu (148201)

“…</p>Results<p>Among the 19,137 new inpatients identified with GI neoplasms in Wuwei, gastric cancer was the leading cause of morbidity, followed by cancers of the esophagus, colorectum, gastric cardia, liver, and pancreas with ASIRs of 21.8, 11.0, 5.8, 5.7, 4.4, and 1.7 per 100,000 person-years, respectively. Overall, there was a steady increase in the ASIR for all GI neoplasms, and male cases were 2.1 times more frequent than female cases. …”

Polymorphisms of −174G>C and −572G>C in the Interleukin 6 (IL-6) Gene and Coronary Heart Disease Risk: A Meta-Analysis of 27 Research Studies by Guo-hua Zheng (172579)

“…On the contrary, the −572C allele was associated with a decreased risk of CHD when compared with the −572G allele (ORs = 0.79, 95%CI = 0.68 to 0.93). …”

DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx by Ping Sun (59933)

“…</p>Results<p>From 1990 to 2019, the global age-specific incidence rate (per 100,000 population) significantly increased from 25.04 (95% confidence interval 18.51, 31.65) to 32.21 (23.73, 40.81) for early-onset CKD. …”

Table_3_Association between dietary approaches to stop hypertension eating pattern and lung cancer risk in 98,459 participants: results from a large prospective study.docx by Zhiyong Zhu (2559349)

“…Lung cancer was identified in 1642 cases over 869807.9 person-years of follow-up, and the overall incidence rate was 0.189 cases/100 person-years. Participants in the highest quartile in the fully adjusted model had a relatively decreased risk of developing lung cancer in comparison to those in the lowest quartile (HR_{quartile 4 versus 1}: 0.647; 95% CI: 0.557, 0.752; P_trend < 0.001). …”

Table_1_Association between dietary approaches to stop hypertension eating pattern and lung cancer risk in 98,459 participants: results from a large prospective study.docx by Zhiyong Zhu (2559349)

“…Lung cancer was identified in 1642 cases over 869807.9 person-years of follow-up, and the overall incidence rate was 0.189 cases/100 person-years. Participants in the highest quartile in the fully adjusted model had a relatively decreased risk of developing lung cancer in comparison to those in the lowest quartile (HR_{quartile 4 versus 1}: 0.647; 95% CI: 0.557, 0.752; P_trend < 0.001). …”