Inhibiting the mu opioid receptor (MOR), Src, Gab-1, PI3 kinase or STAT3 attenuates opioid and growth factor-induced epithelial mesenchymal transition (EMT) in human lung cancer ce... by Frances E. Lennon (541593)

“…A decrease in claudin-1 expression is suggestive of an epithelial mesenchymal transition.…”

Fig 4 - by Rupamanjari Majumder (128411)

“…<p>A-E Effect of applying a light pulse (filled yellow rectangle) (0.092 mW/mm², 100 ms) to different phases of an action potential (AP). …”

Out of Plane Distortions of the Heme <em>b</em> of <em>Escherichia coli</em> Succinate Dehydrogenase by Quang M. Tran (180372)

“…To examine whether heme reduction is an essential step of the catalytic mechanism, we generated a series of site-directed mutations around the heme binding pocket, creating a library of variants with a stepwise decrease in the midpoint potential of the heme from the wild-type value of +20 mV down to −80 mV. …”

Stochastic property of the two-state bacterial receptor model with the multiple methylation sites. by Masatoshi Nishikawa (363723)

“…The activity as the number of active chemoreceptors (red) is plotted as a function of time. For step increase and decrease in chemoattractant concentration (blue), the activity shows response and adaptation. …”

Extracellular Cu inhibits mSlo1 activation by Zhongming Ma (45963)

“…(C) Single channel I-V relation is unaffected by 100 μM Cu (top). Representative traces at +160 mV from a single channel patch show a marked decrease in P (bottom). …”

Proxy-based paleoclimate series for the last 5000 years. by David Kaniewski (218243)

“…Positive scores correspond to higher humidity whereas negative scores indicate dry periods <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071004#pone.0071004-Kaniewski1" target="_blank">[11]</a>; (<b>c</b>) Time-series (5000 BP to present by step of 100 years) of annual precipitation (anomalies from the present in mm/yr) averaged on Southeastern Mediterranean region (longitude 20°E−50°E, latitude 30°N-45°N); the data are reconstructed from pollen data extracted from the European Pollen Database; (<b>d</b>) fluctuations in Nile floods, indicated by lake level variations of Lake Qarun (Fayum depression, Egypt) inferred from paleoshorelines and lake sediments <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071004#pone.0071004-Hassan2" target="_blank">[73]</a>; (<b>e</b>) reconstruction of annual precipitation based on botanical-climatological transfer functions applied to pollen data from Ain Gedi sediments (Dead Sea shore) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071004#pone.0071004-Litt1" target="_blank">[15]</a>; (<b>f</b>) Abundance of Cyperaceae pollen, a marker of fresh water input, in a sediment core from Burullus Lagoon in the north-central Nile Delta <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071004#pone.0071004-Bernhardt1" target="_blank">[14]</a>. …”

Role of Altered Enzyme Quantities on the Integration Properties of DARPP-32 by Maria Lindskog (65533)

“…A decrease in enzyme quantity produces a decrease in the change of PKAc during stimulation (dashed line) and an increase in the phosphoThr34 levels (dotted line). …”

Trajectories of six functions and return map analysis. by Yuji Yamamoto (109076)

“…(<b>f</b>) Logarithmic function, . (<b>a</b>) Asymptotic trajectory to the attractive fixed point as a series of points, which corresponds to the movement of decreasing IPD by the step-towards motion shown in (<b>A</b>). …”

The effect of stress on sound processing increases with repeated exposure. by Ghattas Bisharat (20706928)

“…We found a negative slope in most PPY and PV cells, indicating a decrease in activity as the stress becomes chronic (<i>t</i> test for PPY cells <i>p</i> = 9.8 × 10⁻¹⁴, PV cells <i>p</i> = 0.006) and a positive slope for SST cells indicating an increase in activity with successive applications of the stressor (<i>t</i> test for SST cells <i>p</i> = 9.5 × 10⁻⁰⁶). …”

miR-9 suppressed the expression of cyclin D1 and Ets1 through post- transcriptional repression in gastric cancer cells. by Liduan Zheng (182440)

“…The symbols (* and #) indicate a significant decrease and a significant increase from mock or anti-NC, respectively.…”

Cell-cell fusions occur in <i>par-5</i> loss-of-function mutants. by Jessica H. Shinn-Thomas (847582)

“…<p>Time-lapse images of a <i>par-5(it55)</i> embryo show multiple cell-cell fusion events, as seen in 100% of observed embryos (n = 3). …”

Data Supplement from Epigenetic Targeting of Ovarian Cancer Stem Cells by Yinu Wang (14844702)

“…Low dose SGI-110 induces sustained cell cycle arrest on OC cells. A. Time-course cell cycle analysis of platinum sensitive A2780 ovarian cancer cells and platinum resistant A2780_CR5 and SKOV3 OC cells after 72 hour daily treatment with low dose SGI-110 (100nM). …”

Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant by Abdal-hay, Abdalla

“…Biodegradable hybrid membrane fiber layers containing nano-hydroxyapatite (nHA) particles and poly(lactide)(PLA) nanofibers were coated layer-by-layer (LbL) on AM50 coupons using a facile single-step air jet spinning (AJS) approach. …”
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Effects of carvacrol and physical exercise on motor and memory impairments associated with Parkinson’s disease by Leila HAMZEHLOEI (7576238)

“…The 6-OHDA-lesioned group showed a significant increase in rotational behavior and a decrease in step-through latency in the passive avoidance test compared with the sham group. …”

Comparison of various inducer treatments on physiological and biochemical parameters in plants under drought conditions, relative to both drought-stressed and well-watered control... by Shelina Akter Sheuli (22446598)

“…Each parameter, such as chlorophyll, carotenoids, H₂O₂, proline, peroxidase (POD), glutathione S-transferase (GST) activity, and RWC, is normalized to the control, set at 100. Values exceeding 100 indicate an increase relative to the control, suggesting enhanced effects under treatment, while values below 100 signify a decrease, indicating reduced effectiveness compared to the control.…”

Comparison of various inducer treatments on physiological and biochemical parameters in plants under normal conditions, relative to well-watered control plants. by Shelina Akter Sheuli (22446598)

“…Each parameter—chlorophyll, carotenoids, H₂O₂, proline, peroxidase (POD), and glutathione S-transferase (GST) activity is normalized to the control, set at 100. Values exceeding 100 indicate an increase relative to the control, suggesting enhanced effects under treatment, while values below 100 signify a decrease, indicating reduced effectiveness compared to the control.…”

Model Studies of 6,7-Indolequinone Cofactors of Quinoprotein Amine Dehydrogenases by Yoko Murakami (423119)

“…The rate constants of each step have been determined by the detailed kinetic analysis, and the kinetic deuterium isotope effects have also been examined to confirm the rate-determining step. …”

Simultaneous increase in canonical Wnt signaling and suppression of pAKT result in increased apoptosis of CC cells. by Michael Bordonaro (340595)

“…(B) The steady-state levels of transcriptionally active beta-catenin are not decreased in HCT-116 cells by combined treatment with a HDACi and MK2206. …”

Rab5c overactivation leads to HSPC production defect. by Jian Heng (8698323)

“…Error bars, mean ± SD, ***<i>P</i> < 0.001. (F) WISH analysis shows that <i>cmyb</i> is decreased in embryos of <i>rab5c</i> CA overexpression driven by <i>fli1a</i> promoter. …”

Graphene Growth on Pt(111) by Ethylene Chemical Vapor Deposition at Surface Temperatures near 1000 K by Gregory W. Cushing (1643866)

“…The initial dissociative sticking coefficient <i>S</i>₀(<i>T</i>_g = 300 K, <i>T</i>_s) for ethylene was found to decrease with increasing surface temperature until a temperature of <i>T</i>_s = 850 K was reached whereupon it increased with temperature.…”