Elementary Steps in Olefin Metathesis: Nickelacyclobutanes via Cycloaddition to Nickel Carbenes by Samantha K. Cormier (16872384)

“…This is the sole example to date of an obervable NiCB generated via cycloaddition, beyond the fluorinated examples. Computations pinpoint a decreased energy barrier to cycloreversion, relative to reductive elimination or β-H elimination, as the core requirement to achieve metathesis. …”

Decreased numbers of motor neurons in Tc1 and Dp(16)1Yey mice. by Sheona Watson-Scales (586942)

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

Incubation of V79-CYP3A94/DD-POR cells with Shield-1 leads to a decrease of POR protein. by Ramona Dettwiler (664360)

Table 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.xlsx by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Image 2_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Image 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Decreased production of IL-12p70 and IL-23 in response to LPS+R848 stimulation in frail old individuals. by Nathalie Compté (418458)

STEP in-person sessions. by Shirley Yen (12632685)

“…Results from a pilot RCT demonstrated engagement of the target (positive affect) and a decrease in clinical outcomes (suicidal events; i.e., either a suicide attempt or an emergency intervention for an acute suicidal crisis), providing support to test the clinical effectiveness of STEP in a larger clinical trial with clinical staff implementing the intervention.…”

Posterior mean year-stage detection probabilities (red circles) and 95% Bayesian Credible Intervals (BCI; vertical black lines) of the (A) ≤100 m radius, and (B) infinite radius da... by Taza D. Schaming (8911517)

Diabetic wounds show increased amounts of vessel leakage and decreased pericyte coverage. by Uzoagu A. Okonkwo (8754933)

Lens profiles as Ez (orange lines) force was increased and Az and Pz (green lines) forces were decreased. by Ronald A. Schachar (16674576)

S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis by Xiaolin Liu (403100)

“…We find that gene expression of s100a9 was higher in NAFL group compared with control, and was increased in NASH groups and decreased in NAFL + T2DM group compared with NAFL. …”

Microarray analysis of genes modulated by siRNA treatments. by Giorgia Urbinati (554921)

Changes in CFCP between the original trade network and the network after a specific node is removed. by Heesuk Kang (18086720)

Effects of siRNA TMPRSS2-ERG on ERG protein expression and cell viability. by Giorgia Urbinati (554921)

“…The number of viable cells was measured and 100% cell viability corresponds to the number of living cells incubated only with transfecting agent. *** = <i>p</i><0.001, significant decrease compared to untreated cells or to siRNA Control (Kruskal & Wallis followed by Tukey and Dunnet test).…”

Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking by Lorenza Franciosi (600602)

“…SerpinB3 and Uteroglobin decreased after acute smoke exposure in young non-susceptible individuals exclusively, whereas Peroxiredoxin I, S100A9, S100A8, ALDH3A1 (Aldehyde dehydrogenase 3A1) decreased both in young susceptible and non-susceptible individuals, changes being significantly different between groups for Uteroglobin with iTRAQ and for Serpin B3 with iTRAQ and ELISA measures. …”

D452A, E464A, E470A, and E475A mutations decreased the calcium sensitivity. by Qinghuan Xiao (573411)

Adjustment step size. by Qingnan Ji (22662198)

“…Integration efficiency increases by 18.7%, and computational complexity is significantly reduced, with average computation time decreased by 15.4%. User satisfaction also improves, with a 19.5% increase in experience ratings. …”

Overall survival (OS) of patient with newly diagnosed AML in South Korea, from 2011 to2020 by subpopulation: (a) Overall population, (b) OS by Age group, (c) OS by Treatment, (d) O... by Hyun Jin Han (18592254)