Presentation 2_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-ser... by Matteo Puntoni (4901191)

“…Compared to the 3 years before the outbreak, post-emergency hospitalization rates increased by 23% (Standardized Hospitalization Rate Ratio 1.23, 95% CI 1.20–1.25), whereas Pediatric Emergency Department visits after a sharp decrease returned to pre-pandemic rates (Standardized Incidence Rate Ratio 0.98, 95% CI 0.96–1.00). …”

Data Sheet 1_Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12.docx by Sergey V. Molev (22769330)

“…Finally, a ΔlivKHMGF ΔbrnQ ΔyhjE triple mutant showed no detectable uptake of L-isoleucine and L-valine at substrate concentrations up to 100 μM, implying that if other routes exist, their contribution at physiological substrate levels is negligible.…”

Data Sheet 1_Global, regional, and national burden of sudden infant death syndrome, 1990–2021: a comprehensive analysis of GBD 2021 data with insights into the impact during the CO... by Yuhan Sun (299077)

“…Global DALYs were 2,746,174, at a rate of 2,167.56 per 100,000 infants (95% UI, 1,261.44–2,909.59). …”

Protection by extra virgin olive oil against oxidative stress <i>in vitro</i> and <i>in vivo</i>. Chemical and biological studies on the health benefits due to a major component of... by Miriam Rossi (201573)

“…In addition, EVOO significantly decreased the proliferation of human leukemic THP-1 cells, while it kept the proliferation at about normal levels in rat L6 myoblasts, a non-tumoral skeletal muscle cell line. …”

Specific infectivity of WNV replication complex mutants. by Greta A. Van Slyke (761322)

DataSheet_1_Efficacy and safety of anlotinib plus XELOX regimen as first-line therapy for mCRC: a single-arm, multicenter, phase II study (ALTER-C-001).docx by Bo Song (255492)

Data_Sheet_1_Association of high-estimated glomerular filtration rate with the severity of ischemic stroke during non-vitamin K antagonist oral anticoagulants therapy: a nationwide... by Min Kyoung Kang (3829759)

“…The eGFR of 60 to 89 mL/min/1.73 m² group was associated with a decreased risk of moderate-to-severe stroke severity [hazard ratio (HR)] (0.77, 95% confidence interval (CI) [0.61, 0.98], p = 0.031) compared to the eGFR≥90 mL/min/1.73 m² group. …”

Table_1_Dynamic Changes of Cytokine Profiles and Virological Markers Associated With HBsAg Loss During Peginterferon Alpha-2a Treatment in HBeAg-Positive Chronic Hepatitis B Patien... by Minghui Li (409892)

“…HBsAg disappearance rate was the primary evaluation index at 48 weeks of PEG-IFN treatment.</p>Results<p>Among 100 patients who completed the 48-week PEG-IFN α-2a treatment, 38 patients achieved serum HBeAg disappearance, 25 patients achieved HBeAg seroconversion, 9 patients achieved functional cure, 37 patients had HBsAg decline of ≥1 log IU/ml, and 8 patients produced hepatitis B surface antibody (HBsAb). …”

Table_3_Dynamic Changes of Cytokine Profiles and Virological Markers Associated With HBsAg Loss During Peginterferon Alpha-2a Treatment in HBeAg-Positive Chronic Hepatitis B Patien... by Minghui Li (409892)

“…HBsAg disappearance rate was the primary evaluation index at 48 weeks of PEG-IFN treatment.</p>Results<p>Among 100 patients who completed the 48-week PEG-IFN α-2a treatment, 38 patients achieved serum HBeAg disappearance, 25 patients achieved HBeAg seroconversion, 9 patients achieved functional cure, 37 patients had HBsAg decline of ≥1 log IU/ml, and 8 patients produced hepatitis B surface antibody (HBsAb). …”

Table_2_Dynamic Changes of Cytokine Profiles and Virological Markers Associated With HBsAg Loss During Peginterferon Alpha-2a Treatment in HBeAg-Positive Chronic Hepatitis B Patien... by Minghui Li (409892)

“…HBsAg disappearance rate was the primary evaluation index at 48 weeks of PEG-IFN treatment.</p>Results<p>Among 100 patients who completed the 48-week PEG-IFN α-2a treatment, 38 patients achieved serum HBeAg disappearance, 25 patients achieved HBeAg seroconversion, 9 patients achieved functional cure, 37 patients had HBsAg decline of ≥1 log IU/ml, and 8 patients produced hepatitis B surface antibody (HBsAb). …”

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... by Ying Feng (151159)

“…</p>Results<p>In 2021, the global age-standardized prevalence rate (ASPR) of PCOS was 867.7 per 100,000 [95% UI: 618.7–1,195.3], representing a significant increase of 0.75 compared with 1990 [95% CI: 0.71–0.78]. …”

Stimulus protocols. by Penelope A. McNulty (441014)

“…Self-sustained activity was evident in the right wrist extensors with both stimulus patterns, but not in the right thenar muscles. A: 25 Hz for 2 s then 100 Hz for 2 s then 25 Hz for 3 s, C: ramp stimulus, increasing from 1 Hz to 100 Hz over 5 s and then decreasing to 1 Hz over 5 s.…”

Gene expression of <i>Vegf-A</i> and <i>Mcp-1</i> by qRT-PCR at the outflow vein of AVF three days after fistula placement in <i>Iex-1</i> KO and WT mice. by Akshaar Brahmbhatt (551498)

“…There is a significant decrease in the average gene expression of <i>Vegf-A</i> in the <i>Iex-1</i> KO animals when compared to WT controls (P<0.05). …”

Further Studies on the Buffer-Catalyzed Cleavage and Isomerization of Uridyluridine. Medium and Ionic Strength Effects on Catalysis by Morpholine, Imidazole, and Acetate Buffers He... by Ronald Breslow (1835350)

“…A bifunctional mechanism, in which one step involves simultaneous acid−base catalysis, seems most likely. …”

IFNγ-induced inhibition of <i>C. trachomatis</i> growth in WT MEFs. by Munir A. Al-Zeer (266879)

“…The yield of <i>C. trachomatis</i> (B), but not <i>C. muridarum</i> (D), infectious progeny decreased considerably upon IFNγ stimulation, Infectivity percentage calculated as follows: IFU/ml estimated for each treated monolayer / IFU/ml of control cells ×100. …”

Forecast variation of ecoclimatic suitability between historical climate (current EI) and 2070 projected climate (future EI) from A2 climate scenarios using CSIRO-MK3.0 climate mod... by Sylvain Guichard (659128)

“…<p>a) qualitative variation highlighted the expansion (current EI = 0, future EI>0) and the contraction (current EI>0, future EI = 0) of suitable areas for 2070 projection. b) quantitative variation illustrated climatic suitability increases or decreases. …”

ConPADE: Genome Assembly Ploidy Estimation from Next-Generation Sequencing Data by Gabriel R. A. Margarido (725240)

“…<div><p>As a result of improvements in genome assembly algorithms and the ever decreasing costs of high-throughput sequencing technologies, new high quality draft genome sequences are published at a striking pace. …”

Histological (a, b, c) and immunohistological (d–i) stainings (CD3: d–f; HLA class I expression: g–i) of the EMBs at the initial presentation, at 6 and 12 months follow-up. by Mathias Streitz (33288)

“…The initially increased CD3⁺ T-cells and HLA class I expression decreased at the follow-up EMBs. Original magnification a–f: 200×fold. …”

Inhibition of cilia disassembly protects RGCs and suppresses cell cycling after ONT. by Brian K. A. Choi (7114916)

“…Scale bar = 100 μm. (B) Quantification of RGCs after intravitreal injection of the TBA (n = 4 retinas) or AurA inhibitor I (n = 5 retinas), demonstrating significantly increased RGC survival at 14 days post-ONT compared to DMSO control treatment (**p<0.01). …”

Data Sheet 4_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”