DataSheet_1_Efficacy and safety of anlotinib plus XELOX regimen as first-line therapy for mCRC: a single-arm, multicenter, phase II study (ALTER-C-001).docx by Bo Song (255492)

Data_Sheet_1_Association of high-estimated glomerular filtration rate with the severity of ischemic stroke during non-vitamin K antagonist oral anticoagulants therapy: a nationwide... by Min Kyoung Kang (3829759)

“…The eGFR of 60 to 89 mL/min/1.73 m² group was associated with a decreased risk of moderate-to-severe stroke severity [hazard ratio (HR)] (0.77, 95% confidence interval (CI) [0.61, 0.98], p = 0.031) compared to the eGFR≥90 mL/min/1.73 m² group. …”

Data Sheet 1_Excess mortality in young cancer survivors compared with the general population in Italy: a retrospective study from the Italian population-based cohort of adolescents... by Paolo Giorgi Rossi (9311547)

“…Young adult cancer survivors face a sevenfold increase in all-cause mortality compared to the general population, with a notable rise in both cancer-related and non-cancer deaths. …”

Table_1_Dynamic Changes of Cytokine Profiles and Virological Markers Associated With HBsAg Loss During Peginterferon Alpha-2a Treatment in HBeAg-Positive Chronic Hepatitis B Patien... by Minghui Li (409892)

“…HBsAg disappearance rate was the primary evaluation index at 48 weeks of PEG-IFN treatment.</p>Results<p>Among 100 patients who completed the 48-week PEG-IFN α-2a treatment, 38 patients achieved serum HBeAg disappearance, 25 patients achieved HBeAg seroconversion, 9 patients achieved functional cure, 37 patients had HBsAg decline of ≥1 log IU/ml, and 8 patients produced hepatitis B surface antibody (HBsAb). …”

Table_3_Dynamic Changes of Cytokine Profiles and Virological Markers Associated With HBsAg Loss During Peginterferon Alpha-2a Treatment in HBeAg-Positive Chronic Hepatitis B Patien... by Minghui Li (409892)

“…HBsAg disappearance rate was the primary evaluation index at 48 weeks of PEG-IFN treatment.</p>Results<p>Among 100 patients who completed the 48-week PEG-IFN α-2a treatment, 38 patients achieved serum HBeAg disappearance, 25 patients achieved HBeAg seroconversion, 9 patients achieved functional cure, 37 patients had HBsAg decline of ≥1 log IU/ml, and 8 patients produced hepatitis B surface antibody (HBsAb). …”

Table_2_Dynamic Changes of Cytokine Profiles and Virological Markers Associated With HBsAg Loss During Peginterferon Alpha-2a Treatment in HBeAg-Positive Chronic Hepatitis B Patien... by Minghui Li (409892)

“…HBsAg disappearance rate was the primary evaluation index at 48 weeks of PEG-IFN treatment.</p>Results<p>Among 100 patients who completed the 48-week PEG-IFN α-2a treatment, 38 patients achieved serum HBeAg disappearance, 25 patients achieved HBeAg seroconversion, 9 patients achieved functional cure, 37 patients had HBsAg decline of ≥1 log IU/ml, and 8 patients produced hepatitis B surface antibody (HBsAb). …”

Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor... by Ying Feng (151159)

“…</p>Results<p>In 2021, the global age-standardized prevalence rate (ASPR) of PCOS was 867.7 per 100,000 [95% UI: 618.7–1,195.3], representing a significant increase of 0.75 compared with 1990 [95% CI: 0.71–0.78]. …”

Stimulus protocols. by Penelope A. McNulty (441014)

“…Self-sustained activity was evident in the right wrist extensors with both stimulus patterns, but not in the right thenar muscles. A: 25 Hz for 2 s then 100 Hz for 2 s then 25 Hz for 3 s, C: ramp stimulus, increasing from 1 Hz to 100 Hz over 5 s and then decreasing to 1 Hz over 5 s.…”

Gene expression of <i>Vegf-A</i> and <i>Mcp-1</i> by qRT-PCR at the outflow vein of AVF three days after fistula placement in <i>Iex-1</i> KO and WT mice. by Akshaar Brahmbhatt (551498)

“…There is a significant decrease in the average gene expression of <i>Vegf-A</i> in the <i>Iex-1</i> KO animals when compared to WT controls (P<0.05). …”

Crystal size distributions. by Guilherme A. R. Gualda (161367)

“…(c) 3D view of pumice chip (sample AB-6203F), showing euhedral quartz and feldspar grains (green), magnetite (blue), and pyroxene±biotite (white); notice the overall trend of decreasing numbers of crystals with increasing size; sample is approximately cylindrical, field of view ∼9 mm (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037492#pone.0037492.s001" target="_blank">Movie S1</a> for animated version). …”

2D Conductive Iron-Quinoid Magnets Ordering up to <i>T</i>_c = 105 K via Heterogenous Redox Chemistry by Jordan A. DeGayner (3830680)

“…The oxidized compound, (Me₂NH₂)₂[Fe₂L₃]·2H₂O·6DMF (LH₂ = 2,5-dichloro-3,6-dihydroxo-1,4-benzoquinone) was previously shown to magnetically order below 80 K in its solvated form, with the ordering temperature decreasing to 26 K upon desolvation. Here, we demonstrate this compound to exhibit electrical conductivity values up to σ = 1.4(7) × 10^–2 S/cm (<i>E</i>_a = 0.26(1) cm^–1) and 1.0(3) × 10^–3 S/cm (<i>E</i>_a = 0.19(1) cm^–1) in its solvated and desolvated forms, respectively. …”

Data Sheet 1_Global, regional, and national burden of 34 cancer groups across 204 countries and territories, 1990–2021, and projections to 2050: a systematic analysis of the Global... by Linfeng Zhu (759210)

“…</p>Results<p>In 2021, there were 23.57 million new cases and 9.83 million deaths, with a global age-standardized incidence rate (ASIR) of 275.2 per 100,000 and age-standardized mortality rate (ASMR) of 115.8 per 100,000. …”

Further Studies on the Buffer-Catalyzed Cleavage and Isomerization of Uridyluridine. Medium and Ionic Strength Effects on Catalysis by Morpholine, Imidazole, and Acetate Buffers He... by Ronald Breslow (1835350)

“…A bifunctional mechanism, in which one step involves simultaneous acid−base catalysis, seems most likely. …”

IFNγ-induced inhibition of <i>C. trachomatis</i> growth in WT MEFs. by Munir A. Al-Zeer (266879)

“…The yield of <i>C. trachomatis</i> (B), but not <i>C. muridarum</i> (D), infectious progeny decreased considerably upon IFNγ stimulation, Infectivity percentage calculated as follows: IFU/ml estimated for each treated monolayer / IFU/ml of control cells ×100. …”

Forecast variation of ecoclimatic suitability between historical climate (current EI) and 2070 projected climate (future EI) from A2 climate scenarios using CSIRO-MK3.0 climate mod... by Sylvain Guichard (659128)

“…<p>a) qualitative variation highlighted the expansion (current EI = 0, future EI>0) and the contraction (current EI>0, future EI = 0) of suitable areas for 2070 projection. b) quantitative variation illustrated climatic suitability increases or decreases. …”

ConPADE: Genome Assembly Ploidy Estimation from Next-Generation Sequencing Data by Gabriel R. A. Margarido (725240)

“…<div><p>As a result of improvements in genome assembly algorithms and the ever decreasing costs of high-throughput sequencing technologies, new high quality draft genome sequences are published at a striking pace. …”

Histological (a, b, c) and immunohistological (d–i) stainings (CD3: d–f; HLA class I expression: g–i) of the EMBs at the initial presentation, at 6 and 12 months follow-up. by Mathias Streitz (33288)

“…The initially increased CD3⁺ T-cells and HLA class I expression decreased at the follow-up EMBs. Original magnification a–f: 200×fold. …”

Inhibition of cilia disassembly protects RGCs and suppresses cell cycling after ONT. by Brian K. A. Choi (7114916)

“…Scale bar = 100 μm. (B) Quantification of RGCs after intravitreal injection of the TBA (n = 4 retinas) or AurA inhibitor I (n = 5 retinas), demonstrating significantly increased RGC survival at 14 days post-ONT compared to DMSO control treatment (**p<0.01). …”

Data Sheet 4_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”

Data Sheet 5_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... by Shen Tian (4424170)

“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”