Mode and mechanism of OGDHC inhibition. by Moustafa Elkalaf (441286)

“…<p><b>A.</b> TPMP causes mixed inhibition of OGDHC. Increasing the concentration of TPMP caused a decrease in the Vmax and an increase in Km. …”

Simulation-Based Approach to Data Fusion for Three Different Measures of Caspase Activity by John G Albeck (268792)

“…(C) An increase in T_s to 100 min (D) or a decrease in <i>f</i> to 0.1.</p> <p>(E, F, G) Concordance of data on EC substrate cleavage as obtained from immunoblot, flow cytometry, and live-cell assays in HeLa cells treated with 250 ng/ml (E), 50 ng/ml (F), or 10 ng/ml (G) TRAIL. …”

CK2 inhibition in proliferating cells resulted in accelerated expression of differentiation markers. by Natalia González (362674)

“…(C) Quantification of cell subpopulations present in (B), shows a ~10-fold increase in the percentage of Pax7(-)/ myogenin (+) cells (i.e. differentiating cells) with a concomitant decrease in the percentage of proliferating Pax7(+)/myogenin(-) sub population. mean±SEM, n = 3. …”

Acute suppression of Ezh2 induces apoptosis in pOLs. by Falak Sher (151989)

“…</b> (<b>H</b>) Quantification of apoptotic (cleaved caspase 3-positive) and differentiating (RIP-positive) cells in Ezh2-shRNA treated and control (nc-shRNA) pOLs. Bar graphs represent mean of three independent experiments ± S.D. (Calibration bar in (<b>A</b>) represents 100 micrometers, which is valid for all the photomicrographs (<b>A</b>–<b>F</b>); ** in (<b>H</b>) represents p<0.01).…”

Various types of BR input pressure. by Adam Mahdi (496752)

“…<p>To test our models we applied a number of pressure stimuli: (A) sinusoidal, (B) step increases, (C) square (step increase followed by a step decrease), (D) ramp and triangular. …”

Effects of PP on the proliferation of liver cancer cell lines. by Wenwen Xu (175846)

“…</b> The colony-formation assay demonstrated a dose-dependent decrease in liver cancer cell proliferation (Huh7, Hep3B, HepG2 and SMMC-7721) when exposure to PP. …”

Random Lasing in ZnO Nanopowders Based on Multiphoton Absorption for Ultrafast Upconversion Application by Jiao Tian (583054)

“…This study reports ultraviolet picosecond random lasing (RL) based on multiphoton absorption in zinc oxide (ZnO) nanopowders with a mean size of ∼100 nm under femtosecond optical excitation. …”

Functional annotation of human missense SNVs. by Pete Heinzelman (7509374)

“…Roughly two-thirds display decreased spike binding, one-third display binding similar to wild-type ACE2, and a small fraction display increased binding. …”

Results of MC simulations of VO and agonist infusion. by Johane H. Bracamonte (12883844)

“…<p>Top panels show normalized growth in CellArea for 100 representative simulations (gray lines), with terminal values indicated by black circles; adjacent boxplots reflect the mean, CI50, and CI90 of terminal values for 1000 simulations of a) Untreated VO, c) ISO infusion, and e) AngII infusion. …”

Let-7b targets at TLR4 and regulates TLR4 expression via post-transcriptional suppression. by Gui-gen Teng (380044)

“…A dose-dependent decrease of TLR4 protein was determined with let-7b mimics treatment. …”

Membrane localization of the C-terminal SipC actin-nucleation domain is required for synergy with SopB. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

The STD diet reduced the proportion of γδ T cells. by Julie Christine Antvorskov (329686)

“…(<b>F</b>) Percentages of CD8⁻CD103⁻ γδ T cells was lower in mice on the STD than on the GF diet, with a significant decrease in MLN and PLN. Barplots are mean values ± SEM of two independent experiments with 6 mice in each group. …”

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice by Tatsuya Shimomatsu (1545943)

“…The average number of mast cells was 81, 50, and 12 (magnification, ×100), the mortality rate was 24%, 8%, and 9% and the mean body weight gain was 4.6 g, 8.0 g and 5.1 g, respectively.…”

Glycosaminoglycan (GAG) production from cultured chondrocytes under different oxidative conditions by Kazuo Yudoh (8787)

“…The HOtreated group exhibited a significant decrease in GAG production by chondrocytes as compared with the control group at all incubation times. …”

PFMA-3 induced glutathione and lipid peroxidation production greater than XRT. by Francesca Buontempo (3532004)

“…The regeneration currents recorded were reported as a percentage increase/decrease of the signal in respect to the one recorded at the same tip-dish distance but far away from cells (I_T/I_Tdish). …”

TBr inhibited cell proliferation in leukemia cell lines. by Anup S. Pathania (657368)

“…<p>(A–B) Cell proliferation assay. Cells were treated with 1, 10, 30, 50 and 100 µM concentrations of TBr for 24 and 48 h. …”

Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. by Tomomi Sato (301255)

“…Dotted circle, OT. Scale bar, 100 μm. <b>B</b>. Quantification of <i>pou4f1-hsp70l</i>:GFP intensity in the OT for the experiment shown in A (mean ± s.e.m.; **<i>P</i> < 0.01, ***<i>P</i> < 0.001; n = 8, 10, 16 for AG1478, AG43, DMSO, respectively). …”

DAAP1 depletion results in reduced attachment. by Melissa C. Steele-Ogus (12295373)

“…Unattached cells had a greater decrease in DAAP1 expression (38% ± 6) than attached cells (23% ± 2). …”

Soluble klotho blocks DAG stimulation of exocytotic insertion of pre-docked TRPC6 vesicles. by Jian Xie (629484)

“…<p>(A, B) Tetanus toxin (TTX) acts on synaptobrevin (“Sb2” for synaptobrevin-2) to decrease surface expression of TRPC6 channels. …”