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13281
Transmembrane signaling in cell-derived plasma membrane vesicles.
Published 2013“…(D) The FRET signal increases with the concentration of agonist APEC added to the bulk solution (concentrations indicated above the bars in nM). (E) A dose-dependent increase of the FRET yields <i>EC<sub>50</sub></i> = 100±11 nM; shown are averages and standard deviations of the mean of nine titration experiments each performed on different, individual vesicles.…”
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13282
Loss of <i>faah-1</i> enhances <i>nape-1(OE)</i> phenotypes but suppresses <i>nape-2(OE)</i>.
Published 2014“…(<b>D</b>) NAE levels in <i>nape-1(OE)</i> and <i>faah-1(tm5011); nape-1(OE)</i> grown at 25°C showed a significant linear trend towards increased levels (mean+sd, <i>faah-1(tm5011)</i> n = 9, <i>nape-1(OE)</i> n = 8 and <i>faah-1(tm5011); nape-1(OE)</i> n = 6 replicates, one sample test for deviation from 100% - *p<0.05). …”
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13283
<i>In vivo</i> H<sub>2</sub>S treatment prevents O<sub>2</sub>-induced arrested lung vascular growth.
Published 2014“…Arrows highlight vWF-positive vessels; scale bars represent 100 µm. B. Mean data quantifying the number of vWF positive vessels between groups. …”
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13284
Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain-4
Published 2011“…The effects of neomycin alone on CDP-diacylglycerol were not significant, whereas it exerted a slight but significant increase at the 0.3 mM concentration (Dunett's, p < 0.01) and decrease at the 3 mM concentration (Dunnett, p < 0.01) in [H]phosphatidylinositide levels. …”
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13285
P1 and P2 particles avoid DOX toxicity towards cardiomyocytes.
Published 2017“…<b>(B)</b> Quantitation of the toxicity towards CMs as a measure of the decrease in confluence using the aforementioned mask, normalized to the positive control of Triton X-100. …”
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13286
Impact of 10 mM DCA on proliferation of mammary cell lines after 48 hours determined with fluorescence microscopy.
Published 2017“…Statistical significant reduction of Ki67 was observed in ZMTH3, MTH52C and DT14/06T in comparison to non-treated control and non-neoplastic tissue derived cell line MTH53A. No significant decrease in proliferation could be determined in within neoplastic cell lines (I). …”
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13287
PA5369 Is Involved in Adhesiveness and Ability of MDR25 and MPAO1 to Disrupt Epithelial Integrity
Published 2008“…<div><p>(A) Anti-PA5369 antibodies decrease the adhesiveness of strain MDR25 to Caco-2 monolayers<i>.…”
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13288
Gene expression in primary human skeletal muscle cells after treatment with acylcarnitines.
Published 2013“…<p>mRNA expression of PGC-1α (A), CPT1b (B), CD36 (C), COX1 (D) and AngPL-4 (E) related to β-actin mRNA levels after incubation with 100 µM L-carnitine (L-C), an equimolar mixture of C8:0-, C10:0- and C12:0-acylcarnitine (total 100 µM; AC), 60 µM palmitate (p), or p and AC as indicated. …”
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13289
Effect of galactose treatment on oleic acid metabolism.
Published 2013“…Suppressibility, defined as the ability of the cells to decrease oleic acid oxidation by acutely added glucose, was calculated as: [(1-(oxidation of oleic acid at 5 mM glucose/oxidation of oleic acid at no glucose added))×100%]. …”
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13290
Equilibrium unfolding studies of refolded hVDAC-2 using GdnHCl.
Published 2014“…Solid lines denote fits to a two-state equation, except in the case of 80 mM and 100 mM experiments, wherein a sigmoidal fit was used to illustrate the trend in the dataset. …”
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13291
<i>In vivo</i> inhibition of ADAM15 activity reduces tumor growth.
Published 2016“…Subcutaneous inoculation of shA15UC6 cells (n = 10) in SCID mice led to decreased tumor weight compared to ctlA15UC6 control cells (n = 10) (<i>bottom</i>). …”
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13292
Data_Sheet_1_Coastal Flooding in the Balearic Islands During the Twenty-First Century Caused by Sea-Level Rise and Extreme Events.zip
Published 2021“…We map projected flooded areas under two climate-change-driven mean sea-level rise scenarios (RCP4.5 and RCP8.5), together with the impact of an extreme event defined by the 100-year return level of joint storm surges and waves. …”
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13293
High oxygen concentration resulted in drastically reduced mRNA und protein expression of factors for neurodevelopment and plasticity, and DEX administration reversed these effects.
Published 2017“…We detected in all plasticity factors a significant decrease under hyperoxic conditions for <b>A-E)</b> mRNA expression and <b>F-J)</b> protein expression. …”
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13294
Effect of high-voltage electrical stimulation and topical insulin on experimental cutaneous lesions
Published 2022“…HVES was administered 24 hours after surgery, 30 minutes per day, with a frequency of 100 Hz and a mean voltage of 60 V, maintained at the motor threshold. …”
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13295
The place avoidance test for learning, memory and cognitive functions.
Published 2017“…In this task, the mouse has to learn to avoid a stationary shock zone within a rotating arena using visual cues outside the arena (a). …”
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13296
Defective TGF-β proliferative control in <i>Rb1<sup>ΔL/ΔL</sup></i> and <i>Rb1<sup>ΔL/</sup></i><sup>+</sup> mice.
Published 2013“…Proportions were compared between genotypes using a chi-square test. Scale: 100 µm. † denotes previously published data that has been provided for comparison purposes.…”
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13297
Phenotypic changes following long term hypoxia selection.
Published 2007“…A significant decrease at body weight was found in AF flies (lower panel, <i>p</i><0.01). …”
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13298
SopB inositol phosphatase activity is required for inhibition of <i>Salmonella</i> entry.
Published 2008“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”
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13299
Model for penetratin-phospholipid membranes interactions.
Published 2013“…<p>A) The association of penetratin with PG membranes results in the conformational change of the peptide with α-helix and β-sheet contributions and a decrease in membrane fluidity. …”
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13300
Deletion of miR132/212 influences synaptic transmission and plasticity in the neocortex.
Published 2013“…Whole-cell recording were made at membrane potential of −80 mV in the presence of TTX (1 µM) and picrotoxin (100 µM). Scale bar measures 1 s and 10 pA. B) The superimposition of the average waveform (25 each) of mEPSCs recorded in the fl/fl neuron (black line) and miR-132/212 KO neuron (grey line) shown in A. …”