Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

Species richness (<i>SR</i>, upper panels) and Shannon’s entropy (<i>SE</i>, lower panels) vs. the rate in which new species are trying to invade the community, <i>νN</i>. by Immanuel Meyer (12306666)

“…However, as the number of temporal niches decreases global competition puts a hurdle against invasion, as every invader must compete with niche-specialists. …”

Aβ and 22C11 agonist decreased cholesterol uptake whereas the sAPP-derived peptide and SM-ϕ stimulated increased cholesterol uptake by Caco-2 cells. by Kendra L. Puig (334788)

Differential expression analysis of nuclear transcripts after siAPOBEC3A depletion reveals induction of TP53 targets and decreases in cell cycle and cell growth regulator transcrip... by Mason A. McCool (11889842)

Vasodilator effect of BPP-BrachyNH₂ and captopril (10⁻⁹–3 × 10⁻⁵ M) on rat thoracic aorta. by Daniel Dias Rufino Arcanjo (536744)

Overview of pipeline steps and study design. by Alireza Talesh Jafadideh (14227404)

Port-sourced PM₁₀ (μg/m³) attributable deaths/100,000 population at the 2017 Barcelona neighbourhood level. by Natalie Mueller (3406370)

Two strategies used by patients with lumbar spinal stenosis to alleviate symptoms. by Tatsuya Igawa (5204423)

“…(b) Trunk upright posture with a decreased step length and hip extension angle. …”

Forty-three reflective markers. by Tatsuya Igawa (5204423)

Stepped-Wedge Trial Diagram. by Sugy Choi (800862)

“…This report specifically focuses on Project 3, which involves a stepped-wedge trial with 35 clinics receiving a quality management intervention that includes performance coaching. …”

Data processing and analysis steps. by Alexandra V. Kulinkina (5335058)

Effects of S100A6 on CayBP/SIP-mediated β –catenin degradation. by Xiaoxuan Ning (334218)

“…<p>(A) Co-immunoprecipitation assay showed that truncated mutant CacyBP/SIPΔS100 bind both Skp1 and Siah1, suggesting S100A6 did not affect the formation of Siah1-CacyBP/SIP-Skp1 unbiquitin ligase complex. …”

Reduced cellular glucose uptake in response to insulin and decreased expression of a mitochondrial ETC complex subunit in <i>ALAS1</i>-knockdown C2C12 myocytes. by Shinichi Saitoh (4794345)

Geometric mean anti-<i>Na</i>-GST-1 IgG subclass levels over time. by David J. Diemert (8135568)

Mean survival proportions (to 28 d) for each incision metric score as rated by examiners at 7 d for all treatments combined. by April S. Cameron (8622711)

Deficiency of CRL4^CRBN promotes the destruction of BK channel α subunit. by Tianyu Song (4797417)

An example of three consecutive accretive growth steps. by Nol Chindapol (103374)

Metformin inhibits glutaminase activity in a dose dependent manner: from 17.5% at 10 mM up to 68% at 100 mM (A) (* p<0.05). by M. Mar Díaz-Herrero (646639)

Growth kinetics of the spheroids in the microfluidic device. by Sreerupa Sarkar (9628788)

Optical microscopy images acquired after each consecutive process step of the clearing protocol for a rat liver sample. by R. C. M. Vulders (11846314)