Measured Physical Activity Age by Chirag Patel (12240839)

“…In the following, we trained a neural network to predict age from 115,456 one week-long 100Hz wrist accelerometer recordings from the UK Biobank (mean absolute error=3.7±0.2 years), using a variety of data structures to capture the complexity of real-world activity. …”

DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx by Chen Zhou (466781)

“…Compared with placebo group, plasma active GLP-1 AUEC_0-24h increased by 2.20- and 3.36-fold in the 50 mg and 100 mg cetagliptin groups. A decrease of plasma glucose and increase of insulin and C-peptide were observed following OGTT in cetagliptin groups. …”

Image_1_Anterior thalamic nucleus local field potentials during focal temporal lobe epileptic seizures.pdf by Jaysingh Singh (18844255)

“…Statistically significant changes in LFP-PSD were seen for FAS, FIA, and FBTC. We observed a significant gain in LFP at the lower frequency band during FAS at 4 Hz, FIA, and FBTC at 4, 8, and 16 Hz while also observing increases at higher frequencies during FBTC at 100 and 200 Hz and a decrease during FAS seizures at 32 Hz. …”

Simulation results of MR-PL. by Anyi Yang (16643634)

“…The error bar represents twice variance in type I error rate over 100 replications. Notably, the error bar tends to degenerate to a point for those settings with too small variance. …”

Schwann cell IR and remyelination in the injured sciatic nerve. by Alexander Berg (391857)

“…The distal/proximal ratio for both S100 and MBP IR was reduced. For S100, this decrease was more prominent in <i>GFAP^–/–Vim^–/–</i> mice (B, column one) than in WT mice (A), quantified in (C). …”

PMN-MDSC induce EMT in vitro and in vivo. by Benjamin Toh (204080)

“…Red, S100A4; blue, Heamatoxylin (Nuclear stain). Panel I shows a decrease in the percentage of S100A4⁺ cells in the tumors depleted from PMN-MDSC (depletion scheme A). …”

The effect of Andro alone or in combination with Taxi on MMP loss in HeLa cells. by Mazen Alzaharna (3737878)

“…(E) A representative flow cytometric histograms showing the loss in MMP (decrease in FL2 fluorescence) in HeLa cells treated with 50 μM Andro and/or 100 μM Taxi for 24 or 48 h and stained with JC-1. …”

Characterization of <em>Abcc4</em> Gene Amplification in Stepwise-Selected Mouse J774 Macrophages Resistant to the Topoisomerase II Inhibitor Ciprofloxacin by Béatrice Marquez (193669)

“…Molecular cytogenetics experiments showed that this overexpression is linked to <em>Abcc4</em> gene overrepresentation, grading from a partial trisomy of Chr 14 at the first step of selection (cells exposed to 100 µM ciprofloxacin), to low-level amplifications (around three copies) of <em>Abcc4</em> locus on 1 or 2 Chr 14 (cells exposed to 150 µM ciprofloxacin), followed by high-level amplification <em>of Abcc4</em> as homogeneous staining region (hsr), inserted on 3 different derivative Chromosomes (cells exposed to 200 µM ciprofloxacin). …”

One-way sensitivity analysis to all model parameters. by Anna Miquel-Cases (2635486)

“…The NMB remained cost-effective at all parameters values tested, except at specificity of 55% and sensitivity of 100%, were the NMB became negative. Furthermore, an increase in the proportion of relapses and deaths in the conventional-NACT strategy, an increase in the costs of the R health-state and a decrease in the costs of NX markedly increased cost-effectiveness.…”

<b>Depth-Dependence of Soil Stoichiometry Decoupling in China’s Croplands over the Last Four Decades</b> by Andong Cai (10329365)

“…However, how climate change and nutrient inputs affect cropland C:N:P ratios along soil profiles at large scales remains largely unknown. Here, we assess variations in soil C:N:P ratios across a 0-100 cm soil profile in China’s croplands by conducting repeated soil C, N, and P measurements at 305 resampling sites in 1980s and 2023, totaling 6,405 soil profiles. …”

LTPi is expressed presynaptically. by Joana Lourenço (594392)

“…(H) Population data of PPR in baseline (white bar, open circles) and 20 min after depolarization (grey bar, solid circles). Note a decrease in PPR after the steps, indicating a change (an increase) in the probability of GABA release. …”

RI-OR2-TAT reduces the brain load of microglia and oxidative damage and stimulates neurogenesis in APP/PS1 transgenic mice. by Vadivel Parthsarathy (285723)

“…<p>Representative images of activated microglia in the cortical region of APP/PS1 mouse brains as shown by Iba1 immunostaining in animals treated with (<b>A</b>) 0.9% saline or (<b>B</b>) 100 nmol/kg RI-OR2-TAT in 0.9% saline; (<b>C</b>) quantitative analysis shows a decrease in mean microglial load in APP/PS1 mice treated with RI-OR2-TAT; detection of 8 oxo-guanine in the brains of animals treated with (<b>D</b>) 0.9% saline or (<b>E</b>) 100 nmol/kg RI-OR2-TAT; (<b>F</b>) quantitative analysis shows a decrease in mean 8 oxo-guanine staining in APP/PS1 mice treated with RI-OR2-TAT; detection of immature neurons as stained for doublecortin in the dentate gyrus of APP/PS1 mice treated with (<b>G</b>) 0.9% saline or (<b>H</b>) 100 nmol/kg RI-OR2-TAT; (<b>I</b>) quantitative analysis shows an increase in mean doublecortin staining in APP/PS1 mice treated with RI-OR2-TAT. …”

P1- and P2-mediated delivery of DOX escapes cardiotoxicity associated with free DOX administration. by Sibu P. Kuruvilla (4382191)

“…Further, free DOX mice had a 100% death rate by day 15, while P1- and P2-treated had a 100% survival rate during the monitoring period. …”

Minimum concentration of Amphotericin B in serum according to the formulation, dose, and daily or prolonged intermittent therapeutic regimen by Leticia Aparecida Schiave (8438409)

“…The geometric mean Cmin tended to decrease with a reduction in the dose and frequency of intermittent L-AmB infusions: 357 ng/mL (100 mg 4 to 5 times/week) > 263 ng/mL (50 mg 4 to 5 times/week) > 227 ng/mL (50 mg 1 to 3 times/week). …”

Complementary changes in CS duration and firing rate. by Akshay Markanday (11442518)

“…Solid horizontal lines in A and B represent the mean values during the baseline period (−200 to −100 ms from saccade onset), and horizontal dashed lines represent the threshold (3×SD around the mean). …”

Metalloproteinases cleave CD13 from the surface of FLS. by Rachel L. Morgan (3132747)

“…<p>Five different protease inhibitors were added to FLS cultures covering all classes of proteases. <b>(A)</b> The only inhibitor to decrease shedding of CD13 into the supernatant of the cultures was GM6001. …”

Cell counts in different retinal layers for zebrafish exposed to MNU at baseline and follow-up. by Christoph Tappeiner (444164)

“…<p>A. MNU 50 mg/l group: No relevant decrease in retinal cells was observed (p>0.05). …”

<i>In vitro</i> differentiation of <i>Mecp2</i> wild type ES cells is accompanied by large scale heterochromatin reorganization. by Bianca Bertulat (126768)

“…We noticed a highly significant (p<0.0001) decrease of mean chromocenter number per nucleus within the first two weeks of differentiation. …”

Effect of glutamate (Glut) and 4-AP on CAPs in <i>ex vivo</i> spinal ventral columns. by Yan Fu (110146)

“…<p>(A) Histogram showing an irreversible increase in mean peak CAP amplitudes (normalized to 100% of the CAP amplitude (Pre) prior to glutamate treatment) after 1 mM glutamate treatment. …”

Aortic expression of MMP-2, -3, -8 and -13 mRNA after 6 or 9 months exposure to ¹³⁷Cs. by Clélia Le Gallic (750269)

“…C and D: concerning MMP8 and MMP13, we noticed a significant decrease for ApoE^<b>-/-</b> Cs100 after 6 months exposure. …”