Quantitative Analysis of Lipid Droplet Fusion: Inefficient Steady State Fusion but Rapid Stimulation by Chemical Fusogens by Samantha Murphy (144193)

“…LD fusion involved an initial step in which the two adjacent membranes became continuous (<10 s), followed by the slower merging (100 s) of the neutral lipid cores to produce a single spherical LD. …”

PSimScan: Algorithm and Utility for Fast Protein Similarity Search by Anna Kaznadzey (386409)

“…<div><p>In the era of metagenomics and diagnostics sequencing, the importance of protein comparison methods of boosted performance cannot be overstated. Here we present PSimScan (Protein Similarity Scanner), a flexible open source protein similarity search tool which provides a significant gain in speed compared to BLASTP at the price of controlled sensitivity loss. …”

Formation of multiple bumps. by Yasser Roudi (105094)

“…(D), (E), and (F) are the same quantities as (A), (B) and (C) but 100 time steps after the presentation of the second pattern.…”

Transcriptome-Wide Assessment of Human Brain and Lymphocyte Senescence by Mun-Gwan Hong (271202)

“…Here, we have evaluated mRNA expression profiles as a function of age in two populations; one consisting of 191 individuals with ages-at-death ranging from 65–100 years and with post-mortem brain mRNA measurements of 13,216 genes and a second with 1240 individuals ages 15–94 and lymphocyte mRNA estimates for 18,519 genes.…”

Simulated Data Accuracy Curves by Mitchell Guttman (78794)

“…At a SNR = 2 we detect 100% true positives with almost no false positives.…”

The role of cell density on drug response in multilayered cell culture. by Maria Håkanson (154559)

“…A significant decrease in proliferation compared to a sub-confluent situation was observed at a cell density of 86 cells per pattern. …”

DataSheet1_Prognostic significance of fludeoxyglucose positron emission tomography delta radiomics following bridging therapy in patients with large B-cell lymphoma undergoing CAR... by Colton Ladbury (19768281)

“…A decrease in MTV of at least 90% was associated with improved FFDP (24-month FFDP: 100% vs. 62.4%; p < 0.001). …”

Suppression of [Ca²⁺]_i by inhibiting L-type VDCCs is necessary for bitter tastant-induced bronchodilation of Mch precontracted mouse airways. by Cheng-Hai Zhang (385288)

“…Data on the right panels are mean ± SEM. % relaxation = tension decrease due to chloro divided by tension increase due to Mch, ×100. …”

Trends and correlates of cystic echinococcosis in Chile: 2001–2012 by Soledad Colombe (4374232)

“…The hospitalization rate was found to be overall steadily decreasing from 2001 (7.02 per 100,000) to 2012 (4.53 per 100,000) with a 5% decrease per year (rate ratio = 0.95 [95% CI: 0.94, 0.96]). …”

Optical Stimulation of Zebrafish Hair Cells Expressing Channelrhodopsin-2 by Bryan D. Monesson-Olson (558607)

“…Consistent with the increased variability of first spike latency, we saw a significant decrease in the vector strength of phase-locked spiking during optical stimulation. …”

Xl-VSP1 and Xl-VSP2 function as voltage-regulated 5- and 3-phosphatases. by Wil Ratzan (6569894)

“…(left) Averaged fPLC FRET traces over time during a voltage step from a holding potential of -100 to +160 mV for fPLC co-expressed with either Xl-VSP1 or Xl-VSP2. …”

Random forest identifies metabolites that significantly distinguishes between WT and dKO group of mice. by Samit Ganguly (1792294)

“…RFA identified two groups (WT and KO) with 100% accuracy in both CSF (A) and plasma (B). Metabolites were plotted against their Mean Decrease in Accuracy, calculated by RFA. …”

Sensitivity of simulated pathogen diversity to host lifespan and environmental transmission. by Benjamin Roche (84064)

“…The <i>z</i>-axis corresponds to the mean antigenic diversity over the 40-y period. A decrease in environmental uptake rate (<i>x</i>-axis) dramatically reduces mean antigenic diversity (average of the number of strains) and switches the phylogenetic pattern from one that depicts broad coexistence to an immune escape profile. …”

Glucose Starvation-Induced Dispersal of <em>Pseudomonas aeruginosa</em> Biofilms Is cAMP and Energy Dependent by Tran T. Huynh (143293)

“…In addition, we monitored dispersal photometrically, as a decrease in turbidity/opacity of biofilms pre-grown and starved in continuous flow-cells, in order to evaluate treatments (e.g. inhibitors CCCP, arsenate, chloramphenicol, L-serine hydroxamate) and key mutants altered in biofilm development and dispersal (e.g. …”

The effects of the <i>p_yz</i> strength. by Yong-Jun Shin (184085)

“…<p>(A) As <i>p_yz</i> is decreased, periodic DNA repair-related fluctuation (<i>T</i> = 40 min and amplitude = 100 molecules/cell) is filtered less, so the p53 levels fluctuate more. …”

<i>Gfap</i> gene expression upregulation in hyperinflamed intestinal rat tissue. by Corinna Rosenbaum (2559232)

“…We found increases in <i>Gfap</i> expression in duodenal segments by 6.8-fold and in colonic segments by 5.5-fold with a concurrent decrease of <i>S100b</i> expression to the 0.4-fold. …”

The GRRF results. by John C. Murphy (340256)

“…<p>(A) Importance of meristic counts in predicting individual assignments to four species of <i>Tupinambis</i> lizards based on mean decrease in Gini accuracy as revealed by 100 replicates of 10-fold cross-validation of Guided Regularized Random Forests (GRRF). …”

Hyperoxia Raw Data.xlsx by Benjamin Negrete (22279174)

“…Red drum acclimated to hyperoxia showed lower mean cell hemoglobin content, decreased methemoglobin, and a modest decrease in red blood cell pH. …”

Measured Physical Activity Age by Chirag Patel (12240839)

“…In the following, we trained a neural network to predict age from 115,456 one week-long 100Hz wrist accelerometer recordings from the UK Biobank (mean absolute error=3.7±0.2 years), using a variety of data structures to capture the complexity of real-world activity. …”

DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx by Chen Zhou (466781)

“…Compared with placebo group, plasma active GLP-1 AUEC_0-24h increased by 2.20- and 3.36-fold in the 50 mg and 100 mg cetagliptin groups. A decrease of plasma glucose and increase of insulin and C-peptide were observed following OGTT in cetagliptin groups. …”