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Data_Sheet_1_High-Resolution Image Analysis Reveals a Decrease in Lens Thickness and Cone Density in a Cohort of Young Myopic Patients.docx
Published 2021“…</p><p>Results: With the severity of myopia, the increased AL was associated with thinning of the lens (P < 0.001, 95% CI: −100.42 to −49.76). The thickness of the ORL and choroid decreased significantly (all P < 0.001), whereas the thickness of the GCC and INL decreased only in the outer ring (both P < 0.01). …”
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Blocking the interaction between S100A9 protein and RAGE V domain using S100A12 protein - Fig 4
Published 2018“…<p>(A). Emission spectra of 2 μM S100A9 fluorescence titrations exhibiting decreased fluorescence intensities with increasing concentration of S100A12 at the micromolar level. …”
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Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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206
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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207
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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208
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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209
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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Animation displaying S100A1−MDM2 complex generated via the HADDOCK program.
Published 2020Subjects: -
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Taurine Chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats
Published 2021“…Lymphocytes were cultured at a concentration of 1×106 cells/mL and activated by concanavalin A. …”
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Restoring Specific Lactobacilli Levels Decreases Inflammation and Muscle Atrophy Markers in an Acute Leukemia Mouse Model
Published 2012“…The restoration of <em>Lactobacillus</em> species by oral supplementation with <em>L. reuteri</em> 100-23 and <em>L. gasseri</em> 311476 reduced the expression of atrophy markers (Atrogin-1, MuRF1, LC3, Cathepsin L) in the gastrocnemius and in the tibialis, a phenomenon correlated with a decrease of inflammatory cytokines (interleukin-6, monocyte chemoattractant protein-1, interleukin-4, granulocyte colony-stimulating factor, quantified by multiplex immuno-assay). …”
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220
Mangiferin Decreases Plasma Free Fatty Acids through Promoting Its Catabolism in Liver by Activation of AMPK
Published 2012“…Mangiferin (50, 100, 150 mg/kg BW) decreased dose-dependently FFA and triglycerides (TG) levels in plasma, and their accumulations in liver, but increased the β-hydroxybutyrate levels in both plasma and liver of hyperlipidemic rats. …”