Incomplete Albumin-Cre-mediated deletion of <i>Rps6</i> results in mosaicism for RPS6 expression across the neonatal liver. by Sarah A. Comerford (3854917)

“…After stripping, the blot was incubated with a p³²-radiolabeled 18S rRNA probe. (D) Graph showing quantitation of the Northern blot shown in (C) demonstrating that <i>Rps6</i> mRNA levels are decreased by 50–60% in ΔS6 livers relative to WT. …”

Datasheet1_Comparative effectiveness of standard vs. AI-assisted PET/CT reading workflow for pre-treatment lymphoma staging: a multi-institutional reader study evaluation.pdf by Russell Frood (8485714)

“…</p>Results<p>There was a significant decrease in time between non-AI and AI-assisted reads (median 15.0 vs. 13.3 min, p < 0.001). …”

Data Sheet 1_Host-specific vascular endothelial cell responses to Angiostrongylus vasorum: a comparative in vitro study in red foxes (Vulpes vulpes) and domestic dogs.docx by Belinda Eisenhut (21466943)

“…</p>Discussion<p>These findings corroborate that foxes have developed mechanisms for a regulated immune response following A. vasorum exposure, while dogs exhibit a higher pro-inflammatory reaction, contributing to severe clinical outcomes. …”

Differential antibody and cytokine responses associated with resistance to <i>T. cruzi</i>. by Marianne A. Bryan (246141)

“…<p>These plots model responses in <i>T. cruzi</i> infected C57Bl/6 and Balb/c mice compared to control mice inoculated with heat-inactivated parasite (original data in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g001" target="_blank">Fig 1</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g002" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g003" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g004" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g005" target="_blank">5</a>) and show the association of parasite-specific antibody responses in the blood and spleen with decreased polyclonal antibody responses and differential cytokine expression (kinetics and quality summarized here). …”

The Ipsilateral Retinogeniculate Projection Is Altered in Ten_m3 KO Mice by Catherine A Leamey (62507)

“…</p> <p>(G and H) Plots of the mean ± standard error of the mean (s.e.m.) distribution of the ipsilateral projection along the DV-ML axis in five WT (G) and five KO (H) animals. In WTs, a smooth bell-shaped curve is seen that rises to peak around 30%–40% of the DV-ML axis and decreases to low values by around 60% of the axis. …”

DataSheet_1_Safety and Efficacy of Sintilimab and Anlotinib as First Line Treatment for Advanced Hepatocellular Carcinoma (KEEP-G04): A Single-Arm Phase 2 Study.docx by Xiaofeng Chen (392939)

“…Grade 3 TRAEs occurred in 8 (40.0%) patients, the most common being decreased platelet count (10.0%) and increased γ-glutamyl transferase (10.0%). …”

Upper panel: The minimum-norm solution for the difference between the Grand Means of the tinnitus and the control groups indicates a greater prefrontal activity (dark shading) in t... by Nathan Weisz (3118)

“…</p> The darkest shading corresponds to 100% of the maximum activation (the ligther, the stronger the decrease relative to the maximum). …”

Time-dependent effects of NE/IFN-γ on MHC-I (A), B7-1 (B), IDO (C) and B7-H1 (D) mRNA expression. by Liancai Wang (306725)

Scribble regulates myelin thickness and ERK activation in oligodendrocytes. by Andrew A. Jarjour (343100)

“…<p>A,B,D,E; At P40, decreased myelination of small-diameter axons in both optic nerve (B) and spinal cord (E) of Scribble cKO mice persists relative to wild-type littermates (A,D). …”

Recombinant CCR5-T4L acts as a HIV-1 co-receptor and down-regulates WT-CCR5 expression on the 3T3T4 cell surface. by Qingwen Jin (767337)

“…CCR5 expression was measured using flow cytometry and a PE-conjugated monoclonal antibody (2D7). The averaged mean fluorescence values (MFVs) for CCR5 from three experiments are plotted as a bar diagram, where WT-CCR5 expression after transfection with WT-CCR5 plus empty vector is set at 100. …”

Baseline progression risk for the model in the top part of <b>Table 4</b>, for a non-black participant in the San Francisco Veterans Affairs Medical Center liver studies cohort [17... by Peter Bacchetti (75155)

“…<p>(A) Risk of progression at a time step of 1.5 years given no progression at earlier time steps (<i>hazard</i> of progression). …”

DataSheet_1_A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.... by Savannah M. Rocha (10826524)

“…Results indicated that oral administration of PT150 caused a dose-dependent decrease in replication of SARS-CoV-2 in lung, as well as in expression of ACE2 and TMPRSS2. …”

NSAIDs do not prevent the increase in [Ca²⁺]_cyt induced by Aβ_1–42- oligomers or affect cell ATP levels. by Sara Sanz-Blasco (271498)

“…<i>H</i>. Salicylate 100 µM increased [Ca²⁺]_cyt further in cells treated with Aβ_25–35 (20 µM). …”

Table_1_Medium-chain triglycerides (8:0 and 10:0) increase muscle mass and function in frail older adults: a combined data analysis of clinical trials.pdf by Osamu Ezaki (219242)

Table_2_Medium-chain triglycerides (8:0 and 10:0) increase muscle mass and function in frail older adults: a combined data analysis of clinical trials.pdf by Osamu Ezaki (219242)

Data Sheet 1_Global burden, trends and inequalities of maternal hypertensive disorders among reproductive-age women of advanced maternal age, 1990–2021: a population-based study.pd... by Xuanyu Zhao (5881895)

“…</p>Methods<p>We conducted a population-based study using data from the Global Burden of Disease (GBD) 2021 study, covering 204 countries and territories. …”

Supplementary Material for: A Lentiviral CXCR4 Overexpression and Knockdown Model in Colorectal Cancer Cell Lines Reveals Plerixafor-Dependent Suppression of SDF-1α-Induced Migrati... by Heckmann D. (4129651)

“…Functional CXCR4 knockdown using lentiviral short hairpin RNA (shRNA) vectors significantly decreased the migration behavior in CRC cell lines (p < 0.001), confirming a CXCR4-specific effect. …”

Pioglitazone Improves Fat Distribution, the Adipokine Profile and Hepatic Insulin Sensitivity in Non-Diabetic End-Stage Renal Disease Subjects on Maintenance Dialysis: A Randomized... by Anne Zanchi (645982)

“…This was associated with a 20% increase in hepatic insulin sensitivity without changes in muscle insulin sensitivity, a 12% increase in HDL cholesterol and a 50% decrease in CRP.…”

Data_Sheet_1_One-Year Change in the H2FPEF Score After Catheter Ablation of Atrial Fibrillation in Patients With a Normal Left Ventricular Systolic Function.pdf by Min Kim (218786)

“…Baseline high H₂FPEF scores (≥6) were independently associated with the female sex, left atrium (LA) diameter, LV mass index, pericardial fat volume, and a low estimated glomerular filtration rate. One year after AFCA, decreased ΔH₂FPEF scores_[1−yr] were associated with baseline H₂FPEF scores of ≥6 [OR, 4.19 (95% CI, 2.88–6.11), p < 0.001], no diabetes [OR, 0.60 (95% CI, 0.37–0.98), p = 0.04], and lower pericardial fat volume [OR, 0.99 (95% CI, 0.99–1.00), p = 0.003]. …”

Image 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…Background<p>Oral squamous cell carcinoma (OSCC) is a challenging malignancy with poor prognosis despite therapeutic advancements. …”