Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction by Changhoon Choi (3356525)

“…Depletion of a DNA damage repair gene, DNA-PKcs, by siRNA dramatically increased the sensitivity of HCC cells to proton beams with a decrease in colony survival and an increase in apoptosis. …”

Data Sheet 1_Emotional prompting amplifies disinformation generation in AI large language models.docx by Rasita Vinay (21006911)

“…Introducing polite language to prompt requests yielded significantly higher success rates for disinformation (davinci-002, 79%; davinci-003, 90%; gpt-3.5-turbo, 94%; and gpt-4, 100%). Impolite prompting resulted in a significant decrease in disinformation production across all models (davinci-002, 59%; davinci-003, 44%; and gpt-3.5-turbo, 28%) and a slight reduction for gpt-4 (94%).…”

Predictors of 30-day mortality and the risk of recurrent systemic thromboembolism in cancer patients suffering acute ischemic stroke by Ki-Woong Nam (3829753)

“…</p><p>Aim</p><p>In this study, we evaluate the possibility of D-dimer as a predictor of 30-day mortality in stroke patients with active cancer.…”

p300 expression in melanoma patients. by Anand Rotte (464987)

“…<p>(A) Representative images at 100× (upper panel) and 400× (lower panel) magnification of normal nevi (NN) and dysplastic nevi (DN) with strong and primary melanoma (PM) and metastatic melanoma (MM) with weak nuclear p300 staining. …”

Image_2_Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers.JPEG by Emma Acerbo (10933287)

“…The most prominent alterations concern high-frequency oscillations (HFOs), namely an increase in ripples, a reduction in pathological Fast Ripples (FRs), and a decrease in pathological interictal epileptiform discharges (IEDs).…”

Image_1_Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers.JPEG by Emma Acerbo (10933287)

“…The most prominent alterations concern high-frequency oscillations (HFOs), namely an increase in ripples, a reduction in pathological Fast Ripples (FRs), and a decrease in pathological interictal epileptiform discharges (IEDs).…”

Comparative proteomic analysis of the moderately resistant and susceptible peanut cultivars during infestation by <i>Cylindrocladium parasiticum</i> by Xinyu Chen (47670)

“…However, MAPK signal pathway was more pronounced in moderately resistant peanut cultivar T09. We also observed an increase of CYP73A100 involved in phenylpropanoid and flavonoid biosynthesis pathways in susceptible peanut ecotype P562, while decrease in moderately resistant interaction. …”

DataSheet_1_Nitrogen Enrichment Reduces the Diversity of Bacteria and Alters Their Nutrient Strategies in Intertidal Zones.pdf by Yuan-Feng Xu (13037058)

“…To address this gap, we conducted a two-month mesocosm experiment using six targeted concentrations of total N. …”

Data_Sheet_1_Development of BacMam Induced Hepatitis E Virus Replication Model in Hepatoma Cells to Study the Polyprotein Processing.ZIP by Manjeet Kumar (712166)

“…A 20% decrease in the replicative forms of RNA could be seen in presence of 100 μM Ribavirin after 48 h of treatment. …”

Competitive tuning: Competition's role in setting the frequency-dependence of Ca²⁺-dependent proteins by Daniel R. Romano (4574287)

“…In this work, we view Ca²⁺/CaM as a limiting resource in the signal transduction pathway owing to its low abundance relative to its binding partners. …”

Schematic illustration of the variable-ranking process for the derivation cohort. by Johan Nilsson (364438)

“…<p>Panel (A). Step I: training of the survival model using fivefold cross-validation and a committee machine with 10 members. …”

Cation Vacancies in NiFe2O4 During Heat Treatments at High Temperatures: Structural, Morphological and Magnetic Characterization by Harrison Salazar-Tamayo (8183697)

“…On the other hand, Mössbauer spectrometry showed that there is a decrease in the subspectral areas ratio for Fe3+ cations at tetrahedral (A) and octahedral [B] sites, AA/AB, with the increase of the temperature. …”

Supplementary Material for: Real-world effectiveness of piperacillin/tazobactam with and without linezolid for spontaneous bacterial peritonitis by Quickert S. (12023954)

“…Treatment failure, defined as the need to escalate antibiotic therapy due to in vitro resistance, lack of neutrophil decrease in ascitic fluid, or clinical decision, and 30-day survival were retrospectively assessed. …”

Supplementary Material for: Real-world effectiveness of piperacillin/tazobactam with and without linezolid for spontaneous bacterial peritonitis by Quickert S. (12023954)

“…Treatment failure, defined as the need to escalate antibiotic therapy due to in vitro resistance, lack of neutrophil decrease in ascitic fluid, or clinical decision, and 30-day survival were retrospectively assessed. …”

Table_1_Intratracheal inoculation results in Brucella-associated reproductive disease in male mouse and guinea pig models of infection.DOCX by Martha E. Hensel (6425414)

“…Vaccination resulted in a significant reduction in colonization in the mouse, but this could not be correlated with a decrease in inflammation. …”

The effect of Ingenol-B on the suppressive capacity of elite suppressor HIV-specific CD8+ T cells by Abena K. Kwaa (3997559)

“…<div><p>Background</p><p>Some latency-reversing agents (LRAs) inhibit HIV-specific CD8+ T cell responses. In a prior study of protein kinase C (PKC) agonists, we found that bryostatin-1 inhibited elite controller/suppressor (ES) CD8+ T cell suppressive activity whereas prostratin had no effect. …”

Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome by Yasunori Okabe (170091)

“…When high extracellular Glu was added to the astrocyte cultures and incubated, a time-dependent decrease of extracellular Glu concentration occurred due to Glu clearance by astrocytes. …”

Proliferation of CTS-treated cells. by Rebecca J. Clifford (497197)

“…<p>A) Normal MCF10A cells exhibited a concentration-dependent decrease in BrdU incorporation (proliferation) when treated with 500 nM ouabain, 50 nM bufalin or 100 nM bufalin for 2 hours (p<0.01). …”

Land cover, more than monthly fire weather, drives fire-size distribution in Southern Québec forests: Implications for fire risk management by Jean Marchal (3319485)

“…Fires were highly selective on fuel-type under a wide range of fire weather conditions: specifically, deciduous forest, lakes and to a lesser extent recently burned areas decreased the expected fire size in their vicinity compared to conifer forest. …”

Data_Sheet_1_Health Effects of Metabolic Risks in the United States From 1990 to 2019.docx by Ruifang Chen (2451214)

“…</p>Results<p>In 2019, the age-standardized death and DALY rates attributable to metabolic risks were 174.9 and 4738.7 per 100,000 people, accounting for 33.1% and 18.2% of death and DALY rates from all causes in the US, and there was a decrease by −32.5% and −21.2% in age-standardized death and DALY rates since 1990. …”