Necdin deficiency decreases <i>p16</i> expression and increases <i>Cdk1</i> expression in primary NPCs. by Ryohei Minamide (505053)

Image5_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG by Hamza Kamran (18433152)

“…The 14–22 amide (myr) PKA inhibitor alone elicits ER Ca²⁺ release, and subsequent treatment with D,L-methadone does not cause additional ER Ca²⁺ release, indicating that PKA inhibition is a key step in D,L-methadone-induced ER Ca²⁺ release and can bypass the D,L-methadone-OPRM1-AC-cAMP step. …”

The GTPase RalA Regulates Different Steps of the Secretory Process in Pancreatic β-Cells by Sanda Ljubicic (257524)

“…Silencing of this GTPase in INS-1E cells by RNA interference led to a decrease in secretagogue-induced insulin release. …”

Decreased BK responsiveness of p38 activation is evident in both PS-1 and PS-2 FAD mutant AD fibroblasts. by Graziella Mendonsa (374346)

Image_2_Serum Zinc-α2-Glycoprotein Levels Were Decreased in Patients With Premature Coronary Artery Disease.JPEG by Meijuan Liu (4924417)

“…At the cutoff value of 7.955 μg/mL serum ZAG, the sensitivity and specificity for differentiating patients with PCAD from controls were 50.5 and 78.0%, respectively. The combination of ZAG with other clinical variables including age, gender, BMI, SBP, FBG, TC, HDL-C, Cr, and Urea had significantly improved the diagnosis accuracy with a sensitivity of 82.6%, a specificity of 95.0%, and AUC of 0.957 (95% CI, 0.940–0.975, p < 0.05).…”

Image_1_Serum Zinc-α2-Glycoprotein Levels Were Decreased in Patients With Premature Coronary Artery Disease.JPEG by Meijuan Liu (4924417)

“…At the cutoff value of 7.955 μg/mL serum ZAG, the sensitivity and specificity for differentiating patients with PCAD from controls were 50.5 and 78.0%, respectively. The combination of ZAG with other clinical variables including age, gender, BMI, SBP, FBG, TC, HDL-C, Cr, and Urea had significantly improved the diagnosis accuracy with a sensitivity of 82.6%, a specificity of 95.0%, and AUC of 0.957 (95% CI, 0.940–0.975, p < 0.05).…”

Table_1_Serum Zinc-α2-Glycoprotein Levels Were Decreased in Patients With Premature Coronary Artery Disease.DOCX by Meijuan Liu (4924417)

“…At the cutoff value of 7.955 μg/mL serum ZAG, the sensitivity and specificity for differentiating patients with PCAD from controls were 50.5 and 78.0%, respectively. The combination of ZAG with other clinical variables including age, gender, BMI, SBP, FBG, TC, HDL-C, Cr, and Urea had significantly improved the diagnosis accuracy with a sensitivity of 82.6%, a specificity of 95.0%, and AUC of 0.957 (95% CI, 0.940–0.975, p < 0.05).…”

Protective effect of injected hAFSC as determined by increase of proliferation and decrease of apoptotic tubular cells in glycerol induced ATN kidneys. by Laura Perin (252948)

Stepwise addition of DMSO. by Renquan Ruan (721497)

Overexpression of GFP-tagged ZFP36L2 decreases LHR mRNA endogenously expressed in MLTC-1 cells. by Christopher B. Ball (564991)

The presence of several basal dendrites increases the field sensitivity at the apical dendrites while decreasing the field sensitivity at the soma and basal dendrites. by Florian Aspart (3366014)

Conceptual diagram summarising the three main steps of the analyses. by Nina McLean (4872268)

Lentivirus-mediated FGFR1 overexpression in A549 cells significantly decreased influenza A virus replication. by Xin Liu (43569)

Lead Exposure Inhibits Fracture Healing and Is Associated with Increased Chondrogenesis, Delay in Cartilage Mineralization, and a Decrease in Osteoprogenitor Frequency-5 by Jonathan J. Carmouche (71816)

vFLIP maintains intestinal barrier integrity in a short term model <i>in vivo</i>. by Barbara Ruder (8379354)

A decreased yield of RNP1, RNP2 and RNP5 formation in the presence of protein aGAR1 is counteracted by RNA-S by Bruno Charpentier (9519)

A Bcl-2-BH4 double-glycine variant (I14G/V15G) has a decreased by Giovanni Monaco (452223)

Data_Sheet_1_Immune and Neuroendocrine Trait and State Markers in Psychotic Illness: Decreased Kynurenines Marking Psychotic Exacerbations.docx by Livia De Picker (8319105)

“…Normalization of KA and 3-HK levels between admission and follow-up corresponded to a larger improvement of negative symptoms (r = 0.5, p < 0.030) A reverse association was found between relative improvement of SDST scores and decreasing KA levels (r = 0.5, p < 0.010).…”

MOLM14 cells incubated with Eltrombopag for 6 hours show higher expression of stress response genes. by Anna Kalota (7415)

Optimal MUAC cut-off points by gender and age category for screening individuals with underweight, overweight and obesity. by Sheikh Arafat Rahman (21799685)