Image3_Modification of Fibronectin by Non-Enzymatic Glycation Impairs K+ Channel Function in Rat Cerebral Artery Smooth Muscle Cells.JPEG by Yan Yang (33204)

“…As vascular smooth muscle (VSM) K⁺ channels mediate vasodilation, we hypothesized that modification of fibronectin, via advanced non-enzymatic glycation, would alter signaling of this extracellular matrix protein through these channels. Bovine FN (1 mg/ml) was glycated (gFN) for 5 days using methylglyoxal (50 mM), and albumin was similarly glycated as a non-matrix protein control. …”

Image4_Modification of Fibronectin by Non-Enzymatic Glycation Impairs K+ Channel Function in Rat Cerebral Artery Smooth Muscle Cells.JPEG by Yan Yang (33204)

“…As vascular smooth muscle (VSM) K⁺ channels mediate vasodilation, we hypothesized that modification of fibronectin, via advanced non-enzymatic glycation, would alter signaling of this extracellular matrix protein through these channels. Bovine FN (1 mg/ml) was glycated (gFN) for 5 days using methylglyoxal (50 mM), and albumin was similarly glycated as a non-matrix protein control. …”

Image1_Modification of Fibronectin by Non-Enzymatic Glycation Impairs K+ Channel Function in Rat Cerebral Artery Smooth Muscle Cells.JPEG by Yan Yang (33204)

“…As vascular smooth muscle (VSM) K⁺ channels mediate vasodilation, we hypothesized that modification of fibronectin, via advanced non-enzymatic glycation, would alter signaling of this extracellular matrix protein through these channels. Bovine FN (1 mg/ml) was glycated (gFN) for 5 days using methylglyoxal (50 mM), and albumin was similarly glycated as a non-matrix protein control. …”

Data_Sheet_1_Denitrification Biokinetics: Towards Optimization for Industrial Applications.PDF by Navreet Suri (1506556)

“…The rate and extent of NO₃^– reduction were also affected by NO₂^– accumulation, particularly in incubations with K172, where up to more than a 2-fold rate decrease was observed. The decrease in rate was associated with decreased transcript abundances of denitrification genes (nirS and nosZ) required to produce enzymes for reduction of NO₂^– and N₂O. …”

Prognostic effect of high-flux hemodialysis in patients with chronic kidney disease by X. Li (536560)

“…We initially retrieved 227 studies from the database search. Following a multi-step screening process, eight high-quality studies were selected for our meta-analysis. …”

Changes in the faecal bacterial microbiota during hospitalization of horses with colic and the effect of different causes of colic by Holly L. Stewart, Dipti Pitta, Nagaraju Indugu, Bonnie Vecchiarelli, Julie B. Engiles, Louise L. Southwood (4850500)

“…</p> <p><i>Results</i>: There was a decrease in species richness from admission to day 3/hospital discharge (P = 0.049) and a decrease in species richness (P = 0.005) and Shannon diversity (P = 0.016) in horses with chronic compared to acute colic. …”

Table 1_Laboratory comparison of consumer-grade and research-established wearables for monitoring heart rate, body temperature, and physical acitivity in sub-Saharan Africa.docx by Stefan Mendt (834379)

“…The agreement between the Withing device and the research-established device worn on the wrist (GENEActiv) for measuring the number of steps also decreased during the treadmill phases (first stage: r = 0.48, bias = 0.6 steps/min; fourth stage: r = 0.48, bias = 17.3 steps/min). …”

Oxidative Addition of Iodomethane to Charge-Tuned Rhodium(I) Complexes by Massimiliano Delferro (1359450)

“…Compounds <b>2</b>·X were also reacted with iodomethane, forming complexes [Rh(HEtSNS)(COCH₃)I]X (<b>5·</b>X), stable in solution for a short time, that transform by deprotonation into <b>4</b> and into unidentified decomposition products. …”

Table1_Effects of 3-week repeated cold water immersion on leukocyte counts and cardiovascular factors: an exploratory study.docx by Ninja Versteeg (16894872)

“…</p><p>Methods: A total of n = 12, non-cold-adapted men (age: 25.2 ± 4.0 years; height: 177.8 ± 5.6 cm; weight: 73.8 ± 6.5 kg) were randomly allocated to the CWI or control (CON) group. …”

Data Sheet 1_Longitudinal associations between the COVID-19 pandemic and sleep characteristics in children and parents.docx by Deborah Wernecke (22090103)

“…A moderate correlation was observed between mothers' mental health and boys' sleep quality at ages 5, 6, and 9. …”

Data_Sheet_1_Trends of the Global, Regional, and National Incidence of Measles, Vaccine Coverage, and Risk Factors in 204 Countries From 1990 to 2019.DOCX by Ruitong Wang (4392976)

“…</p>Results<p>Globally, there was a significant decrease in the number (84.18%) and ASR (6.13%, 95% CI: 5.41–6.84%) of measles incidence from 1990 to 2019. …”

Data_Sheet_1_Covid-19 Lockdown in Spring 2020 in France Provided Unexpected Opportunity to Assess Health Impacts of Falls in Air Pollution.docx by Lucie Adélaïde (10951581)

“…The reduction in exposure to air pollution was estimated by calculating the difference between modeled exposure of the population during the strict lockdown and the gradual lifting, and the simulated exposure that would have been observed in the absence of lockdown. A quantitative health impact assessment was used to estimate both the short-term impact of PM₁₀ and NO₂ reductions, and the long-term impact of PM_2.5 and NO₂ reductions on mortality. …”

DataSheet_1_Critical weather limits for paddy rice under diverse ecosystems of India.pdf by Santanu Kumar Bal (16801962)

“…The higher yields may be attributed to a significant difference in bright sunshine hours between reproductive phases of above-average and below-average yield years (ranging from 2.8 to 7.8 hours during P5 stages and 1.7 to 5.1 during P4 stages). …”

Table_1_Multivariate piecewise linear regression model to predict radiosensitivity using the association with the genome-wide copy number variation.xlsx by Joanna Tobiasz (11816504)

“…The weighted mean relative errors (MRE) decreased with increasing the segments' number. The borders of the utmost segments have stabilized after partitioning SF2 into 5 subranges.…”

Data_Sheet_1_Covid-19 Lockdown in Spring 2020 in France Provided Unexpected Opportunity to Assess Health Impacts of Falls in Air Pollution.docx by Lucie Adélaïde (10951581)

“…The reduction in exposure to air pollution was estimated by calculating the difference between modeled exposure of the population during the strict lockdown and the gradual lifting, and the simulated exposure that would have been observed in the absence of lockdown. A quantitative health impact assessment was used to estimate both the short-term impact of PM₁₀ and NO₂ reductions, and the long-term impact of PM_2.5 and NO₂ reductions on mortality. …”

DataSheet1_Glucagon-like peptide-1 receptor agonists as add-on therapy to insulin for type 1 diabetes mellitus.zip by Xinrui Tan (12089750)

“…In addition, there was a decrease in prandial insulin dose (WMD, −4.23 IU; 95% CI, −5.26 to −3.20), basal insulin dose (−2.40 IU; −3.93 to −0.87), and total insulin dose (−5.73 IU; −10.61 to −0.86). …”

Data_Sheet_1_Elevated CO2 Enhances Dynamic Photosynthesis in Rice and Wheat.docx by Huixing Kang (11510365)

“…The substrate effect increased the accumulative carbon gain (ACG) during photosynthetic induction by 45.5% in rice and by 39.3% in wheat, whereas the acclimation effect decreased the ACG by 18.3% in rice but increased it by 7.5% in wheat. …”

Nilotinib inhibits cell viability and neurosphere formation in medulloblastoma cells (MB-PDX and DAOY). by Kirti Kandhwal Chahal (7411091)

“…Nilotinib was observed to be most potent in inhibiting the formation of NS from single cells. (<b>f)</b> A representative Western blot for quantitation of nuclear Gli-1 in MB-PDX and DAOY cells shows a decrease in Gli-1 protein after treatment with 5 μM Nilotinib for 24 hours. …”

Epigenetic silencing of miR-203 in Kazakh patients with esophageal squamous cell carcinoma by MassARRAY spectrometry by Xiaobin Cui (553791)

“…Furthermore, miR-203 expression showed a nearly 4.5-fold decrease in ESCC than NETs (0.206 ± 0.336 vs. 0.908 ± 1.424, <i>P</i> < 0.001) and was significantly associated with lymph node metastasis <i>(P</i> = 0.012). …”

Deleting liver-innervating cholinergic neurons induces beiging of ingWAT. by Jiyeon Hwang (19747297)

“…(I) Western blot images showing a decrease in pS660-HSL expression in ingWAT of experimental mice relative to controls. …”